{"id":329,"date":"2026-10-06T09:00:00","date_gmt":"2026-10-06T09:00:00","guid":{"rendered":"https:\/\/cntumour.com\/cancer\/throat-cancer-pharyngeal-cancer-3\/"},"modified":"2026-10-29T15:53:18","modified_gmt":"2026-10-29T15:53:18","slug":"throat-cancer-pharyngeal-cancer-3","status":"publish","type":"cancer_type","link":"https:\/\/cntumour.com\/zh-hk\/cancer\/throat-cancer-pharyngeal-cancer-3\/","title":{"rendered":"\u5589\u764c\uff08\u54bd\u764c\uff09"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u4e86\u89e3\u5589\u764c\uff08\u54bd\u764c\uff09\u9700\u8981\u6df1\u5165\u4e86\u89e3\u9019\u7a2e\u8907\u96dc\u75be\u75c5\u7684\u6f5b\u5728\u751f\u7269\u5b78\u7279\u5fb5\u3002\u5589\u764c\uff0c\u91ab\u5b78\u4e0a\u7a31\u70ba\u54bd\u764c\uff0c\u8d77\u6e90\u65bc\u5589\u56a8\u7d44\u7e54\uff0c\u7279\u5225\u5f71\u97ff\u54bd\u90e8\uff0d\u5f9e\u9f3b\u5b50\u5f8c\u9762\u5ef6\u4f38\u5230\u98df\u9053\u9802\u90e8\u7684\u4e2d\u7a7a\u7ba1\u3002\u5b83\u5305\u62ec\u9f3b\u54bd\u764c\u3001\u53e3\u54bd\u764c\u548c\u4e0b\u56a5\u764c\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-throat-cancer-pharyngeal-cancer\">\u4ec0\u9ebc\u662f\u5589\u764c\uff08\u54bd\u764c\uff09\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-throat-cancer-pharyngeal-cancer\">\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u75c5\u56e0\u548c\u98a8\u96aa\u56e0\u7d20<\/a><\/li>\n<li><a href=\"#symptoms-of-throat-cancer-pharyngeal-cancer\">\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-throat-cancer-pharyngeal-cancer-and-survival-rates\">\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-throat-cancer-pharyngeal-cancer\">\u5589\u764c\uff08\u54bd\u764c\uff09\u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-throat-cancer-pharyngeal-cancer\">\u4ec0\u9ebc\u662f\u5589\u764c\uff08\u54bd\u764c\uff09\uff1f<\/h2>\n<p>\u7576\u6b63\u5e38\u7d30\u80de\u767c\u751f\u7a81\u8b8a\uff0c\u5c0e\u81f4\u751f\u9577\u548c\u589e\u751f\u5931\u63a7\uff0c\u5f62\u6210\u60e1\u6027\u816b\u7624\u6642\uff0c\u5c31\u6703\u7522\u751f\u764c\u75c7\u3002\u8207\u8a31\u591a\u764c\u75c7\u4e00\u6a23\uff0c\u5589\u764c\u7684\u95dc\u9375\u4ee3\u8b1d\u7279\u5fb5\u662f\u74e6\u4f2f\u683c\u6548\u61c9\uff0c\u9019\u662f\u4e00\u7a2e\u7368\u7279\u7684\u4ee3\u8b1d\u9069\u61c9\uff0c\u764c\u7d30\u80de\u6703\u6025\u5287\u589e\u52a0\u8461\u8404\u7cd6\u6d88\u8017\uff08\u5927\u7d04\u6bd4\u6b63\u5e38\u7d30\u80de\u9ad8 200 \u500d\uff09\uff0c\u4f46\u5373\u4f7f\u5728\u6c27\u6c23\u5145\u8db3\u7684\u689d\u4ef6\u4e0b\uff0c\u5b83\u5011\u4e5f\u4e3b\u8981\u9032\u884c\u7121\u6c27\u7cd6\u89e3\u3002\u9019\u7a2e\u7cd6\u89e3\u8f49\u8b8a\u652f\u6301\u5feb\u901f\u589e\u6b96\u548c\u751f\u9577\uff0c\u70ba\u7d30\u80de\u63d0\u4f9b\u8c50\u5bcc\u7684\u80fd\u91cf\u4f86\u6e90\uff0c\u5118\u7ba1\u5b83\u662f ATP \u751f\u7522\u7684\u4f4e\u6548\u9014\u5f91\u3002<\/p>\n<h3 id=\"global-and-regional-statistics\">\u5168\u7403\u548c\u5340\u57df\u7d71\u8a08<\/h3>\n<p>\u6839\u64da\u4e16\u754c\u885b\u751f\u7d44\u7e54 2024 \u5e74\u5831\u544a\uff0c\u5168\u7403\u6bcf\u5e74\u7d04\u6709 30 \u842c\u65b0\u8a3a\u65b7\u51fa\u54bd\u764c\u3002\u7279\u5225\u662f\u5728\u9999\u6e2f\uff0c\u5589\u764c\u662f\u6bcf\u5e74\u8a3a\u65b7\u51fa\u7684\u5341\u7a2e\u6700\u5e38\u898b\u764c\u75c7\u4e4b\u4e00\uff0c\u9019\u8868\u660e\u4e9e\u6d32\u4eba\u7fa4\uff08\u5c24\u5176\u662f 45-65 \u6b72\u4eba\u7fa4\uff09\u7684\u60a3\u75c5\u7387\u589e\u52a0\u3002<\/p>\n<ul>\n<li>\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u5589\u764c\u5728\u7537\u6027\u4e2d\u767c\u751f\u7387\u66f4\u9ad8\uff0c\u7537\u6027\u7684\u767c\u751f\u7387\u662f\u5973\u6027\u7684 3 \u500d\u3002<\/li>\n<li>\u9999\u6e2f\u7684\u6578\u64da\u986f\u793a\uff0c\u5589\u764c\u75c5\u4f8b\u6025\u5287\u589e\u52a0\uff0c\u8207\u8a72\u5730\u5340\u666e\u904d\u5b58\u5728\u7684\u98f2\u98df\u548c\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u5c0e\u81f4\u7684\u81f4\u764c\u7269\u8cea\u63a5\u89f8\u91cf\u589e\u52a0\u76f8\u5c0d\u61c9\u3002<\/li>\n<\/ul>\n<p>\u4e9e\u6d32\u65cf\u7fa4\u8868\u73fe\u51fa\u7368\u7279\u7684\u8106\u5f31\u6027\uff0c\u5305\u62ec\u6162\u6027\u611f\u67d3\u9ad8\u98a8\u96aa\u75c5\u6bd2\u4e9e\u578b\uff0c\u4f8b\u5982 HPV\uff08\u4eba\u985e\u4e73\u7a81\u75c5\u6bd2\uff09\u611b\u6f51\u65af\u5766-\u5df4\u723e\u75c5\u6bd2 (EBV)\u3002\u6b64\u985e\u611f\u67d3\u5927\u5927\u589e\u52a0\u4e86\u4e9e\u6d32\u5730\u5340\uff08\u5305\u62ec\u9999\u6e2f\uff09\u7684\u54bd\u764c\u98a8\u96aa\u3002<\/p>\n<h3 id=\"emotional-and-physical-impact\">\u60c5\u611f\u548c\u8eab\u9ad4\u5f71\u97ff<\/h3>\n<p>\u88ab\u8a3a\u65b7\u51fa\u60a3\u6709\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u500b\u9ad4\u901a\u5e38\u9762\u81e8\u56b4\u5cfb\u7684\u8eab\u9ad4\u6311\u6230\uff0c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u541e\u56a5\u56f0\u96e3<\/li>\n<li>\u6301\u7e8c\u5589\u56a8\u75db\u548c\u8072\u97f3\u6c99\u555e<\/li>\n<li>\u9ad4\u91cd\u6e1b\u8f15\u548c\u56b4\u91cd\u75b2\u52de<\/li>\n<li>\u547c\u5438\u56f0\u96e3\uff0c\u8655\u65bc\u665a\u671f\u968e\u6bb5<\/li>\n<\/ul>\n<p>\u52a0\u4e0a\u9019\u4e9b\u660e\u986f\u7684\u75c7\u72c0\uff0c\u60a3\u8005\u7d93\u5e38\u6703\u7d93\u6b77\u60c5\u7dd2\u56f0\u64fe\u548c\u5fc3\u7406\u5f71\u97ff\uff0c\u5305\u62ec\u7126\u616e\u3001\u6182\u9b31\u548c\u793e\u4ea4\u9000\u7e2e\u3002\u56e0\u6b64\uff0c\u5fc5\u9808\u63d0\u4f9b\u5bcc\u6709\u540c\u60c5\u5fc3\u7684\u8b77\u7406\uff0c\u4e0d\u50c5\u900f\u904e\u9769\u547d\u6027\u7684\u6cbb\u7642\uff08\u4f8b\u5982 AllCancer \u7684\u4ee3\u8b1d\u7642\u6cd5\uff09\u91dd\u5c0d\u60e1\u6027\u7d30\u80de\uff0c\u800c\u4e14\u9084\u63d0\u4f9b\u5168\u9762\u7684\u5fc3\u7406\u793e\u6703\u652f\u6301\uff0c\u4ee5\u5e6b\u52a9\u60a3\u8005\u5ea6\u904e\u6574\u500b\u65c5\u7a0b\u3002<\/p>\n<h2 id=\"causes-and-risk-factors-of-throat-cancer-pharyngeal-cancer\">\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u75c5\u56e0\u548c\u98a8\u96aa\u56e0\u7d20<\/h2>\n<p>\u8a8d\u8b58\u5589\u764c\u7684\u539f\u56e0\u548c\u98a8\u96aa\u56e0\u7d20\u5c0d\u65bc\u9810\u9632\u548c\u65e9\u671f\u767c\u73fe\u81f3\u95dc\u91cd\u8981\u3002\u98a8\u96aa\u56e0\u7d20\u53ef\u5927\u81f4\u5206\u70ba\u907a\u50b3\u3001\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u985e\u5225\uff1a<\/p>\n<h3 id=\"genetic-risk-factors\">\u907a\u50b3\u98a8\u96aa\u56e0\u7d20<\/h3>\n<p>\u96d6\u7136\u8207\u4e73\u764c\uff08BRCA1\/BRCA2 \u7a81\u8b8a\uff09\u6216\u80ba\u764c\uff08EGFR \u7a81\u8b8a\uff09\u7b49\u764c\u75c7\u76f8\u6bd4\uff0c\u8207\u5589\u764c\u76f4\u63a5\u4e14\u50c5\u76f8\u95dc\u7684\u7279\u5b9a\u57fa\u56e0\u7a81\u8b8a\u7684\u7279\u5fb5\u9084\u4e0d\u90a3\u9ebc\u5ee3\u6cdb\uff0c\u4f46\u6b63\u5728\u9032\u884c\u7684\u7814\u7a76\u5f37\u8abf\u4e86\u8a31\u591a\u907a\u50b3\u6613\u611f\u56e0\u7d20\u3002\u907a\u50b3\u50be\u5411\u6703\u5f71\u97ff\u7d30\u80de DNA \u640d\u50b7\u4fee\u5fa9\u6a5f\u5236\uff0c\u4f7f\u67d0\u4e9b\u500b\u9ad4\u66f4\u5bb9\u6613\u81f4\u764c\u3002<\/p>\n<h3 id=\"environmental-factors\">\u74b0\u5883\u56e0\u7d20<\/h3>\n<p>\u66b4\u9732\u65bc\u81f4\u764c\u74b0\u5883\u56e0\u7d20\u662f\u4e00\u4e9b\u5589\u764c\uff08\u54bd\u764c\uff09\u75c5\u4f8b\u7684\u91cd\u8981\u539f\u56e0\u3002\u74b0\u5883\u56e0\u7d20\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u7159\u8349\u88fd\u54c1\uff08\u5438\u7159\u3001\u5480\u56bc\u7159\u8349\uff09<\/li>\n<li>\u9577\u671f\u63a5\u89f8\u77f3\u68c9\u6216\u6eb6\u5291\u7b49\u5de5\u696d\u6bd2\u7d20<\/li>\n<li>\u81f4\u764c\u75c5\u6bd2\u7684\u6162\u6027\u611f\u67d3\uff0c\u7279\u5225\u662f HPV \u548c EBV\uff08\u5728\u4e9e\u6d32\u975e\u5e38\u6d41\u884c\uff09<\/li>\n<\/ul>\n<p>\u4f8b\u5982\uff0c\u611b\u6f51\u65af\u5766-\u5df4\u723e\u75c5\u6bd2\uff08EBV\uff09\u5c0d\u4e9e\u6d32\u65cf\u7fa4\u9020\u6210\u91cd\u5927\u5f71\u97ff\uff0c\u7279\u5225\u662f\u5c0e\u81f4\u83ef\u5357\u548c\u9999\u6e2f\u7b49\u5730\u5340\u9f3b\u54bd\u764c\u7684\u6d41\u884c\u3002<\/p>\n<h3 id=\"lifestyle-factors\">\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20<\/h3>\n<p>\u5e7e\u7a2e\u751f\u6d3b\u65b9\u5f0f\u884c\u70ba\u6703\u986f\u8457\u589e\u52a0\u5589\u764c\u98a8\u96aa\uff1a<\/p>\n<ul>\n<li>\u904e\u91cf\u98f2\u9152\uff0c\u5c24\u5176\u662f\u8207\u5438\u7159\u7d50\u5408\uff0c\u6703\u500d\u589e\u98a8\u96aa\u3002<\/li>\n<li>\u4e0d\u826f\u98f2\u98df\u7fd2\u6163\u7f3a\u4e4f\u6297\u6c27\u5316\u5291\u548c\u71df\u990a\u7d20\uff0c\u9019\u5728\u52a0\u5de5\u6216\u4fdd\u5b58\u7684\u4e9e\u6d32\u98df\u54c1\u4e2d\u5f88\u5e38\u898b\u3002<\/li>\n<li>\u80a5\u80d6\u8207\u6162\u6027\u767c\u708e\u548c\u652f\u6301\u81f4\u764c\u7684\u4ee3\u8b1d\u8b8a\u5316\u6709\u95dc\u3002<\/li>\n<\/ul>\n<p>\u91cd\u8981\u7684\u662f\uff0c\u764c\u7d30\u80de\u56fa\u6709\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\u2014\u2014\u4f8b\u5982\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u548c\u9ea9\u91af\u80fa\u9178\u7684\u7279\u5b9a\u4f9d\u8cf4\u2014\u2014\u5f37\u8abf\u4e86\u6a19\u9776\u4ee3\u8b1d\u7642\u6cd5\u7684\u6f5b\u5728\u6709\u6548\u6027\u3002\u8d85\u904e 50% \u7684\u764c\u7d30\u80de\u76f4\u63a5\u4f9d\u8cf4\u9ea9\u91af\u80fa\u9178\u4f5c\u70ba\u95dc\u9375\u7684\u80fd\u91cf\u548c\u6838\u82f7\u9178\u4f86\u6e90\uff0c\u9019\u70ba\u5305\u62ec AllCancer \u5728\u5167\u7684\u5168\u7403\u9818\u5148\u8005\u5be6\u8e10\u7684\u5275\u65b0\u4ee3\u8b1d\u7642\u6cd5\u63d0\u4f9b\u4e86\u53ef\u64cd\u4f5c\u7684\u6a5f\u6703\u3002<\/p>\n<h3 id=\"prevention-and-early-detection\">\u9810\u9632\u548c\u65e9\u671f\u767c\u73fe<\/h3>\n<p>\u5728\u9999\u6e2f\u548c\u6574\u500b\u4e9e\u6d32\uff0c\u516c\u5171\u885b\u751f\u6559\u80b2\u6d3b\u52d5\u5f37\u8abf\u7be9\u6aa2\u548c\u65e9\u671f\u767c\u73fe\u7684\u597d\u8655\uff0c\u53ef\u986f\u8457\u6539\u5584\u5b58\u6d3b\u7d50\u679c\u3002\u5efa\u8b70\u7684\u9810\u9632\u63aa\u65bd\u548c\u7be9\u6aa2\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u5b9a\u671f\u7be9\u6aa2\u9ad8\u5371\u96aa\u5e74\u9f61\u5c64<\/li>\n<li>\u4e86\u89e3\u65e9\u671f\u8a0a\u865f\uff08\u6301\u7e8c\u5589\u56a8\u75db\u3001\u6dcb\u5df4\u7d50\u816b\u5927\u3001\u4e0d\u660e\u539f\u56e0\u9ad4\u91cd\u6e1b\u8f15\uff09<\/li>\n<li>\u6539\u8b8a\u751f\u6d3b\u65b9\u5f0f\uff0d\u6e1b\u5c11\u83f8\u8349\u548c\u9152\u7cbe\u7684\u4f7f\u7528\u3001\u6539\u5584\u98f2\u98df\u3001\u63a5\u7a2e HPV \u75ab\u82d7<\/li>\n<\/ul>\n<p>\u9019\u4e9b\u4e3b\u52d5\u63aa\u65bd\u8207\u5148\u9032\u7684\u8a3a\u65b7\u6280\u8853\u4e00\u8d77\uff0c\u5728\u6cbb\u7642\u6548\u679c\u6700\u9ad8\u6642\u7e7c\u7e8c\u5be6\u73fe\u65e9\u671f\u8b58\u5225\u3002\u4ee4\u4eba\u9f13\u821e\u7684\u662f\uff0cAllCancer \u7b49\u6a5f\u69cb\u7a4d\u6975\u6574\u5408\u9810\u9632\u3001\u65e9\u671f\u6aa2\u6e2c\u548c\u5148\u9032\u6cbb\u7642\u7b56\u7565\uff0c\u5728 2025 \u5e74\u5c07\u5589\u764c\uff08\u54bd\u764c\uff09\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002<\/p>\n<p><strong>\u4e86\u89e3 4D \u7642\u6cd5\u5982\u4f55\u6539\u8b8a\u5589\u764c\uff08\u54bd\u764c\uff09\u6cbb\u7642\u2014\u7acb\u5373\u806f\u7e6b AllCancer \u4ee5\u4e86\u89e3\u66f4\u591a\u8cc7\u8a0a\u3002<\/strong><\/p>\n<h2 id=\"symptoms-of-throat-cancer-pharyngeal-cancer\">\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u75c7\u72c0<\/h2>\n<p>\u65e9\u671f\u767c\u73fe\u5589\u764c\uff08\u54bd\u764c\uff09\u53ef\u986f\u8457\u6539\u5584\u6cbb\u7642\u6548\u679c\uff0c\u56e0\u6b64\u8b58\u5225\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u65e9\u671f\u75c7\u72c0\u81f3\u95dc\u91cd\u8981\u3002\u75c7\u72c0\u6700\u521d\u53ef\u80fd\u770b\u8d77\u4f86\u8f15\u5fae\u6216\u4e0d\u660e\u986f\uff0c\u4f46\u901a\u5e38\u96a8\u8457\u75be\u75c5\u7684\u9032\u5c55\u800c\u8b8a\u5f97\u66f4\u52a0\u660e\u986f\u3002<\/p>\n<h3 id=\"common-and-specific-symptoms\">\u5e38\u898b\u548c\u7279\u6b8a\u75c7\u72c0<\/h3>\n<p>\u4e00\u822c\u75c7\u72c0\u901a\u5e38\u53ef\u80fd\u985e\u4f3c\u65bc\u5e38\u898b\u75be\u75c5\uff0c\u4f46\u6301\u7e8c\u7684\u75c7\u72c0\u9700\u8981\u53ca\u6642\u9032\u884c\u91ab\u7642\u8a55\u4f30\uff1a<\/p>\n<ul>\n<li>\u5589\u56a8\u75db\u6301\u7e8c\u5169\u9031\u4ee5\u4e0a<\/li>\n<li>\u541e\u56a5\u56f0\u96e3\u6216\u75bc\u75db\uff08\u541e\u56a5\u56f0\u96e3\uff09<\/li>\n<li>\u4e0d\u660e\u539f\u56e0\u7684\u9ad4\u91cd\u6e1b\u8f15<\/li>\n<li>\u6301\u7e8c\u8072\u97f3\u6c99\u555e\u6216\u8072\u97f3\u8b8a\u5316\u8d85\u904e\u5169\u9031<\/li>\n<li>\u9838\u90e8\u51fa\u73fe\u816b\u584a\u6216\u816b\u8139<\/li>\n<li>\u8207\u8033\u90e8\u611f\u67d3\u7121\u95dc\u7684\u6301\u7e8c\u6027\u8033\u75db<\/li>\n<li>\u54b3\u8840\uff08\u54af\u8840\uff09<\/li>\n<li>\u547c\u5438\u56f0\u96e3\u6216\u547c\u5438\u56f0\u96e3<\/li>\n<li>\u547c\u5438\u6709\u60e1\u81ed\uff08\u53e3\u81ed\uff09<\/li>\n<li>\u6301\u7e8c\u611f\u89ba\u6709\u6771\u897f\u5361\u5728\u5589\u56a8\uff08\u7654\u7403\u75c7\uff09<\/li>\n<li>\u53e3\u8154\u6216\u5589\u56a8\u5340\u57df\u6709\u660e\u986f\u7684\u751f\u9577<\/li>\n<li>\u75b2\u52de\u548c\u5168\u8eab\u4e0d\u9069<\/li>\n<\/ul>\n<h3 id=\"symptom-manifestations-by-stage\">\u6309\u968e\u6bb5\u5283\u5206\u7684\u75c7\u72c0\u8868\u73fe<\/h3>\n<h4>\u65e9\u671f\u968e\u6bb5\uff08\u7b2c 1 \u671f\u548c\u7b2c 2 \u671f\uff09<\/h4>\n<p>\u5728\u65e9\u671f\u968e\u6bb5\uff0c\u75c7\u72c0\u53ef\u80fd\u5f88\u5fae\u5999\uff0c\u6216\u8005\u5f88\u5bb9\u6613\u88ab\u8996\u70ba\u5e38\u898b\u75be\u75c5\uff0c\u4f8b\u5982\u6162\u6027\u54b3\u55fd\u6216\u8f15\u5fae\u7684\u5589\u56a8\u523a\u6fc0\u3002\u5177\u9ad4\u4f86\u8aaa\uff0c\u660e\u986f\u7684\u75c7\u72c0\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u8f15\u5fae\u4f46\u6301\u7e8c\u7684\u5589\u56a8\u4e0d\u9069<\/li>\n<li>\u4e3b\u8981\u8207\u56fa\u9ad4\u98df\u7269\u6709\u95dc\u7684\u9593\u6b47\u6027\u541e\u56a5\u56f0\u96e3<\/li>\n<li>\u5076\u723e\u51fa\u73fe\u8072\u97f3\u6c99\u555e\uff0c\u4f46\u8072\u97f3\u7121\u660e\u986f\u8b8a\u5316<\/li>\n<li>\u4ed4\u7d30\u81ea\u6aa2\u6216\u81e8\u5e8a\u89f8\u8a3a\u53ef\u767c\u73fe\u5589\u56a8\u6216\u9838\u90e8\u6709\u5c0f\u816b\u584a\u6216\u816b\u584a<\/li>\n<\/ul>\n<h4>\u9ad8\u7d1a\u968e\u6bb5\uff08\u7b2c 3 \u548c\u7b2c 4 \u671f\uff09<\/h4>\n<p>\u7531\u65bc\u816b\u7624\u986f\u8457\u751f\u9577\u548c\u53ef\u80fd\u7684\u8f49\u79fb\u64f4\u6563\uff0c\u665a\u671f\u5589\u764c\uff08\u54bd\u764c\uff09\u75c7\u72c0\u660e\u986f\u66f4\u52a0\u660e\u986f\uff1a<\/p>\n<ul>\n<li>\u6301\u7e8c\u6216\u56b4\u91cd\u7684\u5589\u56a8\u75db\u548c\u8033\u75db\uff08\u7a31\u70ba\u8033\u75db\uff09<\/li>\n<li>\u541e\u56a5\u56fa\u9ad4\u98df\u7269\u548c\u6db2\u9ad4\u98df\u7269\u90fd\u975e\u5e38\u56f0\u96e3<\/li>\n<li>\u865b\u5f31\u3001\u75b2\u5026\u3001\u9ad4\u91cd\u660e\u986f\u6e1b\u8f15<\/li>\n<li>\u6301\u7e8c\u8072\u97f3\u6c99\u555e\u5f71\u97ff\u8a00\u8a9e\u548c\u4ea4\u6d41<\/li>\n<li>\u6162\u6027\u54b3\u55fd\u53ef\u80fd\u4f34\u96a8\u5e36\u8840\u7684\u9ecf\u6db2<\/li>\n<li>\u5589\u56a8\u5340\u57df\u6709\u660e\u986f\u53ef\u89f8\u53ca\u7684\u816b\u584a\u6216\u751f\u9577\uff0c\u6216\u9838\u90e8\u6dcb\u5df4\u7d50\u53d7\u7d2f<\/li>\n<li>\u7531\u65bc\u816b\u7624\u751f\u9577\u5c0e\u81f4\u6c23\u9053\u963b\u585e\u800c\u5c0e\u81f4\u547c\u5438\u56f0\u96e3<\/li>\n<\/ul>\n<h3 id=\"tumor-biology-and-symptomatology\">\u816b\u7624\u751f\u7269\u5b78\u548c\u75c7\u72c0\u5b78<\/h3>\n<p>\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u75c7\u72c0\u7279\u5fb5\u8207\u816b\u7624\u7684\u751f\u9577\u3001\u4f4d\u7f6e\u548c\u764c\u7d30\u80de\u7684\u751f\u7269\u7279\u6027\u76f4\u63a5\u76f8\u95dc\u3002\u75bc\u75db\u3001\u541e\u56a5\u56f0\u96e3\u548c\u547c\u5438\u963b\u585e\u7b49\u75c7\u72c0\u662f\u7531\u65bc\u816b\u7624\u751f\u9577\u640d\u5bb3\u6b63\u5e38\u89e3\u5256\u7d50\u69cb\u548c\u529f\u80fd\u800c\u5f15\u8d77\u7684\u3002\u4f8b\u5982\uff0c\u541e\u56a5\u56f0\u96e3\u53cd\u6620\u4e86\u54bd\u9053\u4e2d\u816b\u7624\u7d44\u7e54\u7684\u76f4\u63a5\u6a5f\u68b0\u5e79\u64fe\u3002<\/p>\n<p>\u7531\u65bc\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u7279\u5fb5\uff08\u4f8b\u5982\u74e6\u4f2f\u683c\u6548\u61c9\uff0c\u764c\u7d30\u80de\u6bd4\u5065\u5eb7\u7d30\u80de\u6d88\u8017\u66f4\u591a\u7684\u8461\u8404\u7cd6\uff09\uff0c\u96a8\u8457\u75be\u75c5\u7684\u9032\u5c55\uff0c\u901a\u5e38\u6703\u51fa\u73fe\u9ad4\u91cd\u6e1b\u8f15\u548c\u75b2\u52de\uff0c\u53cd\u6620\u51fa\u80fd\u91cf\u9700\u6c42\u589e\u52a0\u548c\u71df\u990a\u7f3a\u4e4f\u3002<\/p>\n<p>\u65e9\u671f\u8b58\u5225\u548c\u8aee\u8a62\u53ef\u986f\u8457\u63d0\u9ad8\u6cbb\u7642\u6548\u679c\u4e26\u63d0\u9ad8\u5b58\u6d3b\u7387\u3002\u5982\u679c\u75c7\u72c0\u6301\u7e8c\u8d85\u904e\u5169\u9031\uff0c\u8acb\u7acb\u5373\u8aee\u8a62\u60a8\u7684\u91ab\u7642\u670d\u52d9\u63d0\u4f9b\u8005\uff0c\u9019\u8207\u6211\u5011\u5728 AllCancer \u4fc3\u9032\u65e9\u671f\u6aa2\u6e2c\u4e26\u986f\u8457\u6539\u5584\u9810\u5f8c\u7684\u76ee\u6a19\u4fdd\u6301\u4e00\u81f4\u3002<\/p>\n<h2 id=\"stages-of-throat-cancer-pharyngeal-cancer-and-survival-rates\">\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/h2>\n<h3 id=\"stage-1-throat-cancer-pharyngeal-cancer\">\u7b2c 1 \u671f \u2013 \u5589\u764c\uff08\u54bd\u764c\uff09<\/h3>\n<p>\u5728\u7b2c 1 \u671f\uff0c\u5589\u764c\u4ecd\u5c40\u9650\u65bc\u539f\u767c\u5668\u5b98\u5167\uff0c\u901a\u5e38\u5c40\u9650\u65bc\u5c0f\u816b\u584a\uff08\u5927\u5c0f\u5c0f\u65bc 2 \u516c\u5206\uff09\uff0c\u4e14\u6c92\u6709\u5340\u57df\u6dcb\u5df4\u7d50\u53d7\u7d2f\u6216\u9060\u7aef\u8f49\u79fb\u3002<\/p>\n<ul>\n<li>\u5e38\u898b\u7684\u6cbb\u7642\u65b9\u6cd5\u5305\u62ec\u653e\u5c04\u6cbb\u7642\u548c\u624b\u8853\uff0c\u91dd\u5c0d\u5c40\u90e8\u816b\u7624\u4ee5\u6700\u5927\u9650\u5ea6\u5730\u63d0\u9ad8\u6cbb\u7652\u7387\u3002<\/li>\n<li>\u7b2c 1 \u671f\u7684\u9810\u5f8c\u53cd\u6620\u4e86\u9ad8\u6709\u6548\u6027\uff0c5\u5e74\u5b58\u6d3b\u7387\u9054\u5230\u7d0480-90%\u3002<\/li>\n<li>\u900f\u904e\u5e38\u898f\u7be9\u6aa2\u548c\u4ed4\u7d30\u76e3\u6e2c\u6301\u7e8c\u7684\u5589\u56a8\u75c7\u72c0\u9032\u884c\u65e9\u671f\u767c\u73fe\uff0c\u5c0d\u6210\u529f\u7684\u7d50\u679c\u6709\u5f88\u5927\u5e6b\u52a9\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-2-throat-cancer-pharyngeal-cancer\">\u7b2c 2 \u671f \u2013 \u5589\u764c\uff08\u54bd\u764c\uff09<\/h3>\n<p>2 \u671f\u5589\u764c\u901a\u5e38\u6d89\u53ca\u8f03\u5927\u7684\u816b\u7624\uff082-4 \u516c\u5206\uff09\u6216\u9644\u8fd1\u7d50\u69cb\u7684\u6700\u5c0f\u7a0b\u5ea6\u7684\u53d7\u7d2f\uff0c\u4f46\u4ecd\u6c92\u6709\u5927\u91cf\u6dcb\u5df4\u7d50\u64f4\u6563\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u9078\u64c7\u64f4\u5927\u5230\u5c07\u624b\u8853\u8207\u8f14\u52a9\u653e\u5c04\u6cbb\u7642\u76f8\u7d50\u5408\uff0c\u4ee5\u78ba\u4fdd\u7d9c\u5408\u6cbb\u7642\u3002<\/li>\n<li>\u7b2c 2 \u671f \u7684\u5b58\u6d3b\u7387\u4ecd\u7136\u5f88\u9ad8\uff0c5 \u5e74\u5b58\u6d3b\u7387\u7d71\u8a08\u6578\u64da\u5728 65-80% \u4e4b\u9593\uff0c\u53d6\u6c7a\u65bc\u816b\u7624\u7684\u7cbe\u78ba\u4f4d\u7f6e\u548c\u91ab\u7642\u4fdd\u5065\u7684\u53ef\u53ca\u6027\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-3-throat-cancer-pharyngeal-cancer\">\u7b2c 3 \u671f \u2013 \u5589\u764c\uff08\u54bd\u764c\uff09<\/h3>\n<p>\u5230\u4e86\u7b2c 3 \u671f\uff0c\u5589\u764c\u8868\u73fe\u51fa\u66f4\u660e\u986f\u7684\u9032\u5c55\uff0c\u901a\u5e38\u662f\u7531\u65bc\u5340\u57df\u6dcb\u5df4\u7d50\u8f49\u79fb\u6216\u76f8\u7576\u5927\u7684\u816b\u7624\u5c3a\u5bf8\uff08\u901a\u5e38\u5927\u65bc 4 \u516c\u5206\uff09\u6216\u4fb5\u8972\u6027\u751f\u9577\u5f71\u97ff\u9644\u8fd1\u7684\u89e3\u5256\u7d50\u69cb\u4e26\u986f\u8457\u640d\u5bb3\u529f\u80fd\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u7b56\u7565\u5305\u62ec\u591a\u6a21\u5f0f\u6cbb\u7642\uff0c\u7d50\u5408\u624b\u8853\u3001\u653e\u5c04\u6cbb\u7642\u3001\u5316\u5b78\u6cbb\u7642\u6216\u65b0\u578b\u6a19\u9776\u6cbb\u7642\u65b9\u6cd5\uff0c\u5f37\u8abf\u5c0d\u75be\u75c5\u50b3\u64ad\u7684\u6700\u4f73\u63a7\u5236\u3002<\/li>\n<li>\u60a3\u8005\u7684 5 \u5e74\u5b58\u6d3b\u7387\u986f\u8457\u4e0b\u964d\uff0c\u7d04 50-65%\uff0c\u51f8\u986f\u4e86\u7acb\u5373\u7a4d\u6975\u6cbb\u7642\u4ecb\u5165\u7684\u91cd\u8981\u6027\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-4-throat-cancer-pharyngeal-cancer\">\u7b2c 4 \u671f \u2013 \u5589\u764c\uff08\u54bd\u764c\uff09<\/h3>\n<p>\u665a\u671f\u5589\u764c\uff08\u7b2c 4 \u671f\uff09\u5448\u73fe\u6d89\u53ca\u80ba\u3001\u809d\u7b49\u9060\u7aef\u5668\u5b98\u7684\u8f49\u79fb\u6027\u75c5\u8b8a\uff0c\u6216\u5c0d\u9130\u8fd1\u7d44\u7e54\u7684\u986f\u8457\u7d50\u69cb\u6d78\u6f64\u3002\u9019\u63d0\u51fa\u4e86\u660e\u986f\u7684\u81e8\u5e8a\u6311\u6230\uff0c\u9700\u8981\u4fc2\u7d71\u6cbb\u7642\u4f86\u6709\u6548\u63a7\u5236\u75be\u75c5\u9032\u5c55\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u65b9\u5f0f\u63a2\u7d22\u5168\u8eab\u5316\u7642\u3001\u6a19\u9776\u6cbb\u7642\u548c\u514d\u75ab\u7642\u6cd5\u30024D \u4ee3\u8b1d\u7642\u6cd5\u7b49\u5275\u65b0\u7642\u6cd5\u65e8\u5728\u5229\u7528\u764c\u75c7\u4ee3\u8b1d\u4e2d\u56fa\u6709\u7684\u751f\u7269\u80fd\u91cf\u5f31\u9ede\u3002<\/li>\n<li>4 \u671f\u5589\u764c\u7684\u5b58\u6d3b\u7387\u96d6\u7136\u76f8\u7576\u4f4e\uff0c\u4f46\u4ecd\u53ef\u5be6\u73fe\uff0c\u5927\u7d04\u6578\u64da\u986f\u793a 3 \u81f3 5 \u5e74\u5b58\u6d3b\u7387\u70ba 20-30%\uff0c\u9019\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u53d6\u6c7a\u65bc\u5168\u9762\u7684\u91ab\u7642\u4fdd\u5065\u670d\u52d9\u548c\u500b\u4eba\u5316\u3001\u5275\u65b0\u7684\u6cbb\u7642\u7ba1\u7406\u3002<\/li>\n<\/ul>\n<p>\u5118\u7ba1\u5b58\u5728\u9019\u4e9b\u6311\u6230\uff0c\u4ee3\u8b1d\u816b\u7624\u5b78\u548c\u6a19\u9776\u6cbb\u7642\u7684\u5148\u9032\u5275\u65b0\u63d0\u4f9b\u4e86\u5e0c\u671b\u548c\u6f5b\u5728\u7684\u6162\u6027\u75c5\u7ba1\u7406\u9014\u5f91\uff0c\u8207 AllCancer \u5728\u4e9e\u6d32\u548c\u5168\u7403\u764c\u75c7\u8b77\u7406\u8f49\u578b\u7684\u6f38\u9032\u9858\u666f\u76f8\u4e00\u81f4\u3002<\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-throat-cancer-pharyngeal-cancer\">\u5589\u764c\uff08\u54bd\u764c\uff09\u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/h2>\n<p>\u4e86\u89e3\u50b3\u7d71\u7642\u6cd5\u5728\u7ba1\u7406\u4e0a\u7684\u5c40\u9650\u6027 <strong>\u5589\u764c\uff08\u54bd\u764c\uff09<\/strong> \u6709\u52a9\u65bc\u63a2\u7d22\u65b0\u7684\u6cbb\u7642\u524d\u6cbf\u3002\u50b3\u7d71\u7684\u6cbb\u7642\u65b9\u5f0f\uff08\u4e3b\u8981\u662f\u624b\u8853\u3001\u653e\u5c04\u6cbb\u7642\u548c\u5316\u7642\uff09\u5747\u6709\u986f\u8457\u7684\u7f3a\u9ede\uff0c\u70ba\u60a3\u8005\u5e36\u4f86\u4e86\u56b4\u5cfb\u7684\u6311\u6230\uff0c\u5c24\u5176\u662f\u665a\u671f\u60a3\u8005\u3002<\/p>\n<h3 id=\"chemotherapy-associated-toxicities-and-limitations\">\u5316\u7642\u76f8\u95dc\u7684\u6bd2\u6027\u548c\u5c40\u9650\u6027<\/h3>\n<p>\u5316\u7642\u4ecd\u7136\u662f\u54bd\u764c\u6cbb\u7642\u7684\u57fa\u77f3\uff0c\u4f46\u5176\u4fc2\u7d71\u6027\u610f\u5473\u8457\u5065\u5eb7\u7d30\u80de\u4e0d\u53ef\u907f\u514d\u5730\u53d7\u5230\u5f71\u97ff\u3002\u6839\u64da JAMA Oncology \u7684\u6578\u64da\uff0c\u5927\u7d04 78% \u63a5\u53d7\u54bd\u764c\u5316\u7642\u7684\u60a3\u8005\u6703\u51fa\u73fe\u9aa8\u9ad3\u6291\u5236\u3002\u9019\u7a2e\u4f75\u767c\u75c7\u6703\u5c0e\u81f4\u55dc\u4e2d\u6027\u767d\u8840\u7403\u6e1b\u5c11\u3001\u8ca7\u8840\u548c\u611f\u67d3\u6613\u611f\u6027\u589e\u52a0\uff0c\u56b4\u91cd\u5f71\u97ff\u60a3\u8005\u7684\u751f\u6d3b\u8cea\u7d20\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u9ad8\u9054 23% \u7684\u5589\u764c\uff08\u54bd\u764c\uff09\u5316\u7642\u8207\u5fc3\u81df\u6bd2\u6027\u6709\u95dc\uff0c\u9019\u56b4\u91cd\u9650\u5236\u4e86\u6cbb\u7642\u5291\u91cf\u548c\u6301\u7e8c\u6642\u9593\uff0c\u5c0d\u6cbb\u7642\u7684\u6709\u6548\u6027\u63d0\u51fa\u4e86\u6311\u6230\u3002\u5fc3\u81df\u6bd2\u6027\u5e36\u4f86\u4e86\u66f4\u591a\u554f\u984c\uff0c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u5fc3\u5f8b\u4e0d\u6574\u548c\u50b3\u5c0e\u7570\u5e38<\/li>\n<li>\u65e9\u767c\u6027\u5fc3\u808c\u75c5\u8b8a<\/li>\n<li>\u5145\u8840\u6027\u5fc3\u81df\u8870\u7aed<\/li>\n<\/ul>\n<p>\u6b64\u5916\uff0c\u6301\u7e8c\u5641\u5fc3\u548c\u5614\u5410\u7b49\u56b4\u91cd\u80c3\u8178\u9053\u53cd\u61c9\u6703\u5c0e\u81f4\u60a3\u8005\u71df\u990a\u4e0d\u8db3\uff0c\u7531\u65bc\u71df\u990a\u72c0\u6cc1\u4e0d\u4f73\u800c\u986f\u8457\u524a\u5f31\u514d\u75ab\u9632\u79a6\u80fd\u529b\uff0c\u5c0d\u75be\u75c5\u7d50\u679c\u7522\u751f\u8ca0\u9762\u5f71\u97ff\u3002<\/p>\n<h3 id=\"drawbacks-associated-with-radiation-therapy\">\u8207\u653e\u5c04\u6cbb\u7642\u76f8\u95dc\u7684\u7f3a\u9ede<\/h3>\n<p>\u653e\u5c04\u6cbb\u7642\u96d6\u7136\u5c0d\u5589\u764c\uff08\u54bd\u764c\uff09\u6cbb\u7642\u81f3\u95dc\u91cd\u8981\uff0c\u4f46\u4e5f\u6709\u4e00\u4e9b\u660e\u986f\u7684\u9650\u5236\u3002\u653e\u5c04\u6cbb\u7642\u6703\u9020\u6210\u56b4\u91cd\u7684\u9644\u5e36\u7d44\u7e54\u640d\u50b7\uff0c\u9010\u6f38\u5c0e\u81f4\u9031\u908a\u5065\u5eb7\u7d44\u7e54\u60e1\u5316\u3002\u9577\u671f\u8f3b\u5c04\u526f\u4f5c\u7528\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u53e3\u4e7e\u75c7\uff08\u53e3\u4e7e\uff09\uff0c\u56b4\u91cd\u5f71\u97ff\u60a3\u8005\u7684\u751f\u6d3b\u8cea\u7d20\u3001\u98f2\u98df\u7fd2\u6163\u548c\u8a00\u8a9e\u80fd\u529b<\/li>\n<li>\u541e\u56a5\u56f0\u96e3\u548c\u72f9\u7a84\u5f71\u97ff\u5145\u8db3\u7684\u71df\u990a<\/li>\n<li>\u8f3b\u5c04\u5f15\u8d77\u7684\u7e96\u7dad\u5316\u6703\u5f71\u97ff\u5468\u570d\u808c\u8089\u7d44\u7e54\u7684\u6d3b\u52d5\u6027\u548c\u8cea\u91cf<\/li>\n<li>\u984e\u9aa8\u653e\u5c04\u6027\u9aa8\u58de\u6b7b (ORN)\uff0c\u5c0e\u81f4\u9aa8\u9abc\u66b4\u9732\u548c\u611f\u67d3<\/li>\n<\/ul>\n<p>\u6b64\u5916\uff0c\u653e\u5c04\u6cbb\u7642\u6703\u986f\u8457\u589e\u52a0\u672a\u4f86\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa\uff0c\u6839\u64da\u300aJAMA Oncology\u300b\uff082023\uff09\u767c\u5e03\u7684\u6578\u64da\uff0c\u7814\u7a76\u5831\u544a\u6cbb\u7642\u5f8c 10 \u5e74\u5167\u7e7c\u767c\u6027\u764c\u75c7\u98a8\u96aa\u589e\u52a0\u4e86 300%\u3002<\/p>\n<h3 id=\"risks-and-constraints-of-surgical-intervention\">\u624b\u8853\u4ecb\u5165\u7684\u98a8\u96aa\u548c\u9650\u5236<\/h3>\n<p>\u6cbb\u7642\u54bd\u764c\u7684\u624b\u8853\u65b9\u6cd5\uff0c\u5305\u62ec\u5ee3\u6cdb\u5207\u9664\u548c\u9838\u90e8\u6e05\u6383\uff0c\u53ef\u80fd\u6703\u56b4\u91cd\u640d\u5bb3\u60a3\u8005\u7684\u529f\u80fd\u3001\u7f8e\u89c0\u548c\u751f\u6d3b\u8cea\u7d20\u3002\u8207\u624b\u8853\u4ecb\u5165\u76f8\u95dc\u7684\u4e3b\u8981\u98a8\u96aa\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u56b4\u91cd\u611f\u67d3\u548c\u50b7\u53e3\u7652\u5408\u5ef6\u9072\uff0c\u5ef6\u9577\u4f4f\u9662\u548c\u5fa9\u539f\u6642\u9593<\/li>\n<li>\u8072\u97f3\u3001\u8a00\u8a9e\u6216\u541e\u56a5\u80fd\u529b\u7684\u6c38\u4e45\u6027\u8b8a\u5316\uff0c\u5c0e\u81f4\u56b4\u91cd\u7684\u5fc3\u7406\u56f0\u64fe<\/li>\n<li>\u6bc0\u5bb9\uff0c\u5c0e\u81f4\u56b4\u91cd\u7684\u5fc3\u7406\u548c\u5fc3\u7406\u5065\u5eb7\u5f8c\u907a\u75c7\uff0c\u5305\u62ec\u6182\u9b31\u548c\u7126\u616e<\/li>\n<li>\u91cd\u8981\u89e3\u5256\u7d50\u69cb\u9762\u81e8\u5c0e\u81f4\u6c38\u4e45\u6027\u6b98\u75be\u6216\u767c\u75c5\u7684\u98a8\u96aa<\/li>\n<\/ul>\n<h3 id=\"reduced-efficacy-of-conventional-therapies-in-advanced-stage-throat-cancer-phary\">\u665a\u671f\u5589\u764c\uff08\u54bd\u764c\uff09\u50b3\u7d71\u7642\u6cd5\u7684\u7642\u6548\u964d\u4f4e<\/h3>\n<p>\u50b3\u7d71\u6cbb\u7642\u96d6\u7136\u5728\u65e9\u671f\u968e\u6bb5\u5be6\u65bd\u76f8\u7576\u6709\u6548\uff0c\u4f46\u901a\u5e38\u5728\u665a\u671f\u6216\u8f49\u79fb\u6027\u5589\u764c\uff08\u54bd\u764c\uff09\u4e2d\u8868\u73fe\u51fa\u986f\u8457\u8f03\u4f4e\u7684\u6210\u529f\u7387\u3002\u6839\u64da\u6700\u8fd1\u7684\u7d71\u5408\u5206\u6790\u6578\u64da\uff0c\u5728\u8f49\u79fb\u6027\u75be\u75c5\u60c5\u6cc1\u4e0b\u806f\u5408\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\u7684\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR) \u9060\u4f4e\u65bc 21%\uff0c\u9019\u5f37\u8abf\u4e86\u8feb\u5207\u9700\u8981\u6539\u9032\u3002<\/p>\n<h3 id=\"metabolic-resistance-mechanisms-in-throat-cancer-pharyngeal-cancer\">\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236<\/h3>\n<p>\u50b3\u7d71\u7642\u6cd5\u7684\u4e00\u500b\u8feb\u5207\u9650\u5236\u662f\u764c\u7d30\u80de\u900f\u904e\u57f9\u990a\u4e0d\u540c\u7684\u62b5\u6297\u6a5f\u5236\u4f86\u5feb\u901f\u9069\u61c9\u3002\u5177\u9ad4\u4f86\u8aaa\uff0c\u54bd\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u53ef\u5851\u6027\u548c\u5f37\u5927\u7684\u5167\u5728\u6297\u85e5\u6027\u9014\u5f91\u3002\u6700\u8fd1\u7684\u7814\u7a76\u8868\u660e\uff0c\u764c\u7d30\u80de DNA \u4fee\u5fa9\u9176\u7684\u6d3b\u6027\u589e\u52a0\u4e86 400%\uff0c\u56b4\u91cd\u6291\u5236\u4e86\u5316\u7642\u85e5\u7269\u548c\u653e\u5c04\u6cbb\u7642\u5f15\u8d77\u7684 DNA \u640d\u50b7\u7684\u6548\u679c\u3002\u9019\u4e9b\u6a5f\u5236\u8b49\u5be6\u4e86\u8feb\u5207\u9700\u8981\u63a2\u7d22\u76f4\u63a5\u91dd\u5c0d\u9019\u4e9b\u8106\u5f31\u6027\u7684\u65b0\u578b\u4ee3\u8b1d\u7642\u6cd5\u3002<\/p>\n<h3 id=\"limitations-specific-to-hong-kong-and-asian-populations\">\u9999\u6e2f\u548c\u4e9e\u6d32\u6c11\u773e\u7279\u6709\u7684\u9650\u5236<\/h3>\n<p>\u8a8d\u8b58\u5230\u5340\u57df\u6cbb\u7642\u7684\u5c40\u9650\u6027\u81f3\u95dc\u91cd\u8981\u3002\u5728\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u80cc\u666f\u4e0b\uff0c\u5ef6\u9072\u8a3a\u65b7\u3001\u91ab\u7642\u4fdd\u5065\u7372\u53d6\u4e0d\u5747\u3001\u793e\u6703\u7d93\u6fdf\u969c\u7919\u548c\u516c\u773e\u610f\u8b58\u6709\u9650\u7b49\u56e0\u7d20\u52a0\u5287\u4e86\u9019\u4e9b\u6311\u6230\u3002\u5c0d\u764c\u75c7\u6aa2\u6e2c\u6aa2\u67e5\u7684\u6587\u5316\u7336\u8c6b\u5f88\u5927\u7a0b\u5ea6\u4e0a\u5c0e\u81f4\u4e86\u8a3a\u65b7\u5ef6\u9072\uff0c\u4e26\u96a8\u5f8c\u964d\u4f4e\u4e86\u6cbb\u7642\u6709\u6548\u7387\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u4e9e\u6d32\u4eba\u7fa4\u7684\u751f\u5316\u548c\u907a\u50b3\u8b8a\u7570\u4e5f\u6703\u5f71\u97ff\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\u7684\u4e0d\u826f\u53cd\u61c9\u3002\u9999\u6e2f\u7684\u4e9e\u6d32\u7279\u5b9a\u6578\u64da\u8868\u660e\uff0c\u5c0d\u56b4\u91cd\u4e3b\u52d5\u6bd2\u6027\u7684\u654f\u611f\u6027\u66f4\u9ad8\uff0c\u5c0e\u81f4\u8f03\u65e9\u505c\u6b62\u6cbb\u7642\uff0c\u5c0d\u60a3\u8005\u7684\u6574\u9ad4\u9810\u5f8c\u548c\u751f\u5b58\u6a5f\u6703\u7522\u751f\u8ca0\u9762\u5f71\u97ff\u3002<\/p>\n<h3 id=\"conclusion-why-the-shift-towards-advanced-therapies-is-crucial\">\u7d50\u8ad6\uff1a\u70ba\u4ec0\u9ebc\u5411\u5148\u9032\u7642\u6cd5\u7684\u8f49\u8b8a\u81f3\u95dc\u91cd\u8981<\/h3>\n<p>\u9451\u65bc\u9019\u4e9b\u9650\u5236\uff0c\u66f4\u6709\u6548\u3001\u66f4\u6709\u91dd\u5c0d\u6027\u548c\u751f\u7269\u529b\u5b78\u5408\u7406\u7684\u6cbb\u7642\u65b9\u6cd5\u7684\u5fc5\u8981\u6027\u8b8a\u5f97\u986f\u800c\u6613\u898b\u3002\u4ee3\u8b1d\u816b\u7624\u5b78\u548c4D\u6cbb\u7642\u65b9\u6cd5\u662f\u900f\u904e\u8afe\u8c9d\u723e\u734e\u8a8d\u53ef\u7684\u7814\u7a76\u958b\u767c\u51fa\u4f86\u7684\uff0c\u4e26\u5728\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u548cMD\u5b89\u5fb7\u68ee\u7b49\u9818\u5148\u6a5f\u69cb\u5be6\u65bd\uff0c\u900f\u904e\u76f4\u63a5\u91dd\u5c0d\u8207\u8461\u8404\u7cd6\u548c\u8c37\u6c28\u9170\u80fa\u76f8\u95dc\u7684\u764c\u7d30\u80de\u4ee3\u8b1d\u4f9d\u8cf4\u6027\uff0c\u63d0\u4f9b\u4e86\u6709\u5e0c\u671b\u7684\u66ff\u4ee3\u65b9\u6848\u4f86\u6e1b\u8f15\u9019\u4e9b\u7f3a\u9ede\u3002<\/p>\n<p>\u9f13\u52f5\u6574\u9ad4\u8b77\u7406\u4ee5\u53ca\u4ee3\u8b1d\u8abf\u7bc0\u7b49\u5275\u65b0\u7642\u6cd5\u4ecd\u7136\u81f3\u95dc\u91cd\u8981\u3002\u63d0\u9ad8\u610f\u8b58\u3001\u65e9\u671f\u6aa2\u6e2c\u5be6\u8e10\u3001\u516c\u773e\u6559\u80b2\u4ee5\u53ca\u9999\u6e2f\u91ab\u7642\u4fdd\u5065\u751f\u614b\u7cfb\u7d71\u5167\u5f37\u6709\u529b\u7684\u5340\u57df\u5408\u4f5c\u53ef\u4ee5\u986f\u8457\u63d0\u9ad8\u5589\u764c\uff08\u54bd\u764c\uff09\u7684\u6cbb\u7642\u6548\u679c\u3002\u6700\u7d42\uff0c\u6e1b\u5c11\u50b3\u7d71\u65b9\u6cd5\u7684\u9650\u5236\u5c07\u70ba\u986f\u8457\u6539\u5584\u4e9e\u6d32\u548c\u5168\u7403\u60a3\u8005\u7684\u6cbb\u7642\u6548\u679c\u92ea\u5e73\u9053\u8def\u3002<\/p>\n<p>\u8981\u4e86\u89e3\u6709\u95dc\u6539\u8b8a\u5589\u764c\uff08\u54bd\u764c\uff09\u7ba1\u7406\u7684\u5148\u9032\u4ee3\u8b1d\u7642\u6cd5\u548c\u6301\u7e8c\u5275\u65b0\u7684\u66f4\u591a\u8cc7\u8a0a\uff0c <a href=\"\/zh-hk\/treatment-cancer\/\">\u4e86\u89e3 4D \u7642\u6cd5\u5982\u4f55\u6539\u8b8a\u5589\u764c\uff08\u54bd\u764c\uff09\u6cbb\u7642\u3002<\/a><\/p>\n<h2>4D \u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u76844D \u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u555f\u52d5\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u30022024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u8cea\u7d20\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u555f\u52d5<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7e3d\u7d50<\/strong><\/h2>\n<p>4D \u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u53c3\u8003\u6587\u737b<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u7acb\u5373\u9810\u7d04<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p class=\"ac-blog-disclaimer\"><em>\u91ab\u7642\u514d\u8cac\u8072\u660e\uff1a\u672c\u6587\u50c5\u7528\u65bc\u4e00\u822c\u6559\u80b2\uff0c\u4e0d\u80fd\u53d6\u4ee3\u5408\u683c\u81e8\u5e8a\u91ab\u751f\u7684\u5efa\u8b70\u3002\u6cbb\u7642\u6c7a\u5b9a\u61c9\u57fa\u65bc\u500b\u4eba\u7684\u8a3a\u65b7\u3001\u5206\u671f\u3001\u75c5\u7406\u548c\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002\u5982\u679c\u60a8\u767c\u73fe\u6301\u7e8c\u6216\u4ee4\u4eba\u64d4\u6182\u7684\u75c7\u72c0\uff0c\u8acb\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u3002<\/em><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u4e86\u89e3\u5589\u764c\uff08\u54bd\u764c\uff09\u9700\u8981\u6df1\u5165\u4e86\u89e3\u9019\u7a2e\u8907\u96dc\u75be\u75c5\u7684\u6f5b\u5728\u751f\u7269\u5b78\u7279\u5fb5\u3002<\/p>","protected":false},"featured_media":205,"menu_order":7,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-329","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"version-history":[{"count":2,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/329\/revisions"}],"predecessor-version":[{"id":588,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/329\/revisions\/588"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/media\/205"}],"wp:attachment":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/media?parent=329"}],"curies":[{"name":"\u53ef\u6fd5\u6027\u7c89\u5291","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}