{"id":360,"date":"2026-08-05T09:00:00","date_gmt":"2026-08-05T09:00:00","guid":{"rendered":"https:\/\/cntumour.com\/cancer\/head-and-neck-cancer-head-and-neck-carcinoma-cancer-types\/"},"modified":"2026-10-29T13:38:05","modified_gmt":"2026-10-29T13:38:05","slug":"head-and-neck-cancer-head-and-neck-carcinoma-cancer-types","status":"publish","type":"cancer_type","link":"https:\/\/cntumour.com\/zh-hk\/cancer\/head-and-neck-cancer-head-and-neck-carcinoma-cancer-types\/","title":{"rendered":"\u982d\u9838\u764c"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u982d\u9838\u764c\uff08Head And Neck Carcinoma\uff09\u662f\u6307\u8d77\u6e90\u65bc\u982d\u9838\u90e8\u5340\u57df\u7d44\u7e54\u6216\u5668\u5b98\u7684\u4e00\u7d44\u764c\u75c7\uff0c\u5305\u62ec\u53e3\u8154\u3001\u54bd\u5589\uff08\u54bd\uff09\u3001\u5589\u90e8\uff08\u5589\uff09\u3001\u9f3b\u8154\u548c\u553e\u6db2\u817a\u3002\u7576\u9019\u4e9b\u5340\u57df\u7684\u6b63\u5e38\u7d30\u80de\u767c\u751f\u7a81\u8b8a\u6642\uff0c\u9019\u4e9b\u764c\u75c7\u5c31\u6703\u958b\u59cb\uff0c\u5c0e\u81f4\u751f\u9577\u5931\u63a7\u548c\u816b\u7624\u5f62\u6210\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-head-and-neck-cancer-head-and-neck-carcinoma\">\u4ec0\u9ebc\u662f\u982d\u9838\u764c\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-head-and-neck-cancer-head-and-neck-carcinoma\">\u982d\u9838\u764c\u7684\u75c5\u56e0\u8207\u98a8\u96aa\u56e0\u7d20<\/a><\/li>\n<li><a href=\"#symptoms-of-head-and-neck-cancer-head-and-neck-carcinoma\">\u982d\u9838\u764c\u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-head-and-neck-cancer-head-and-neck-carcinoma-and-survival-rates\">\u982d\u9838\u764c\u7684\u5206\u671f\u8207\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-head-and-neck-cancer-head-and-neck-carc\">\u982d\u9838\u764c\u50b3\u7d71\u7642\u6cd5\u7684\u9650\u5236<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-head-and-neck-cancer-head-and-neck-carcinoma\">\u4ec0\u9ebc\u662f\u982d\u9838\u764c\uff1f<\/h2>\n<p>\u4e86\u89e3\u982d\u9838\u764c\u6d89\u53ca\u8a8d\u8b58\u764c\u7d30\u80de\u5feb\u901f\u7e41\u6b96\u4e26\u9003\u907f\u6b63\u5e38\u7d30\u80de\u63a7\u5236\u7684\u751f\u7269\u6a5f\u5236\u3002\u9019\u4e9b\u764c\u7d30\u80de\u7684\u4e00\u500b\u986f\u8457\u7684\u4ee3\u8b1d\u7279\u5fb5\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u4ee3\u8b1d\u7684\u9ad8\u5ea6\u4f9d\u8cf4\uff0c\u88ab\u63cf\u8ff0\u70ba\u74e6\u723e\u5821\u6548\u61c9\uff0c\u5176\u4e2d\u764c\u7d30\u80de\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u5927\u7d04\u662f\u5065\u5eb7\u7d30\u80de\u7684 200 \u500d\u3002\u9019\u7a2e\u4ee3\u8b1d\u9069\u61c9\u70ba\u65e8\u5728\u7834\u58de\u764c\u7d30\u80de\u5167\u7368\u7279\u7684\u71df\u990a\u4f9d\u8cf4\u6027\u548c\u80fd\u91cf\u7522\u751f\u9014\u5f91\u7684\u6a19\u9776\u6cbb\u7642\u63d0\u4f9b\u4e86\u6a5f\u6703\u3002<\/p>\n<p>\u6839\u64da\u4e16\u754c\u885b\u751f\u7d44\u7e54 (WHO, 2024) \u7684\u6578\u64da\uff0c\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u982d\u9838\u764c\u6bcf\u5e74\u5f71\u97ff\u7d04 90 \u842c\u540d\u65b0\u60a3\u8005\uff0c\u4f7f\u5176\u6210\u70ba\u5168\u7403\u7b2c\u516d\u5927\u5e38\u898b\u764c\u75c7\u3002\u5728\u4e9e\u6d32\uff0c\u767c\u75c5\u7387\u5c24\u5176\u9ad8\uff0c\u9999\u6e2f\u6bcf\u5e74\u7d04\u6709 1,500 \u4f8b\u65b0\u75c5\u4f8b\uff0c\u53cd\u6620\u4e86\u5730\u5340\u7684\u751f\u6d3b\u65b9\u5f0f\u7fd2\u6163\u3001\u907a\u50b3\u6613\u611f\u6027\u4ee5\u53ca\u8207\u4e9e\u6d32\u4eba\u53e3\u7d50\u69cb\u76f8\u95dc\u7684\u81f4\u764c\u56e0\u7d20\u7684\u66b4\u9732\u300245 \u6b72\u81f3 70 \u6b72\u4e4b\u9593\u7684\u7537\u6027\u6700\u5e38\u53d7\u5230\u5f71\u97ff\uff0c\u5118\u7ba1\u8fd1\u5e74\u4f86\u5e74\u8f15\u65cf\u7fa4\u7684\u8a3a\u65b7\u7387\u6709\u6240\u4e0a\u5347\u3002<\/p>\n<p>\u982d\u9838\u764c\u7684\u8a3a\u65b7\u901a\u5e38\u6703\u5e36\u4f86\u60c5\u7dd2\u56f0\u64fe\u548c\u8eab\u9ad4\u6311\u6230\uff0c\u5f9e\u800c\u986f\u8457\u6539\u8b8a\u60a3\u8005\u7684\u751f\u6d3b\u8cea\u7d20\u3002\u5e38\u898b\u7684\u7d93\u9a57\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u6301\u7e8c\u75b2\u52de\u548c\u6975\u5ea6\u4e0d\u9069<\/li>\n<li>\u9032\u98df\u3001\u541e\u56a5\u6216\u6e05\u6670\u8aaa\u8a71\u56f0\u96e3<\/li>\n<li>\u5f71\u97ff\u60a3\u8005\u81ea\u5c0a\u548c\u793e\u4ea4\u4e92\u52d5\u7684\u660e\u986f\u7578\u5f62<\/li>\n<li>\u4ee5\u7126\u616e\u3001\u6182\u9b31\u70ba\u7279\u5fb5\u7684\u5fc3\u7406\u8ca0\u64d4<\/li>\n<\/ul>\n<p>\u8003\u616e\u5230\u9019\u4e9b\u56b4\u91cd\u7684\u5f71\u97ff\uff0c\u5c0d\u8a72\u75be\u75c5\u7684\u65e9\u671f\u767c\u73fe\u548c\u6e96\u78ba\u4e86\u89e3\u4e0d\u50c5\u53ef\u4ee5\u63d0\u4f9b\u66f4\u597d\u7684\u9810\u5f8c\uff0c\u800c\u4e14\u53ef\u4ee5\u986f\u8457\u63d0\u9ad8\u751f\u6d3b\u8cea\u7d20\u3002\u900f\u904e James Allison \u535a\u58eb\u548c Gregg Semenza \u535a\u58eb\u7b49\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u652f\u6301\u7684\u6df1\u5165\u7814\u7a76\uff0c\u65b0\u7642\u6cd5\u91dd\u5c0d\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u63d0\u4f9b\u5148\u9032\u7684\u6cbb\u7642\u9078\u64c7\uff0c\u4f8b\u5982 HK \u4ee3\u8b1d\u7642\u6cd5\uff0c\u5b83\u7368\u7279\u5730\u5229\u7528\u4e86\u764c\u7d30\u80de\u7684\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027\u3002<\/p>\n<h3 id=\"cancer-cells-glucose-dependency-and-warburg-effect\">\u764c\u7d30\u80de\u7684\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027\u548c Warburg \u6548\u61c9<\/h3>\n<p>\u764c\u7d30\u80de\u7684\u80fd\u91cf\u4ee3\u8b1d\u5b58\u5728\u6839\u672c\u5dee\u7570\u3002\u8207\u4e3b\u8981\u900f\u904e\u7c92\u7dda\u9ad4\u6c27\u5316\u78f7\u9178\u5316\u7522\u751f\u80fd\u91cf\u7684\u5065\u5eb7\u7d30\u80de\u4e0d\u540c\uff0c\u5373\u4f7f\u5728\u6c27\u6c23\u5145\u8db3\u7684\u60c5\u6cc1\u4e0b\uff0c\u764c\u7d30\u80de\u4e5f\u4e3b\u8981\u5229\u7528\u7cd6\u9175\u89e3\u2014\u2014\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u79d1\u5b78\u5bb6\u5967\u6258\u00b7\u74e6\u723e\u5821\u535a\u58eb\u767c\u73fe\u4e86\u9019\u4e00\u73fe\u8c61\u3002\u764c\u7d30\u80de\u5c0d\u8461\u8404\u7cd6\u7684\u5f37\u70c8\u9700\u6c42\u88ab\u4ee3\u8b1d\u96c6\u4e2d\u6cbb\u7642\u6240\u5229\u7528\uff0c\u65e8\u5728\u9078\u64c7\u6027\u5730\u98e2\u9913\u764c\u7d30\u80de\uff0c\u4f8b\u5982 AllCancer \u7684 HK \u4ee3\u8b1d\u7642\u6cd5\u7b49\u5275\u65b0\u3002<\/p>\n<p>\u9019\u7a2e\u7406\u89e3\u4f7f\u60a3\u8005\u548c\u91ab\u7642\u4fdd\u5065\u63d0\u4f9b\u8005\u80fd\u5920\u63a2\u7d22\u6a19\u9776\u6cbb\u7642\uff0c\u4e0d\u50c5\u95dc\u6ce8\u50b3\u7d71\u6cbb\u7642\uff0c\u9084\u95dc\u6ce8\u7cbe\u78ba\u7684\u4ee3\u8b1d\u64cd\u4f5c\uff0c\u5f9e\u800c\u63d0\u9ad8\u53cd\u61c9\u7387\u4e26\u6539\u5584\u751f\u5b58\u7d50\u679c\u3002\u5167\u90e8\u57fa\u56e0\u7d44\u8a55\u4f30\u53ef\u4ee5\u9032\u4e00\u6b65\u8a73\u7d30\u8aac\u660e\u7cbe\u78ba\u7684\u6cbb\u7642\u7b56\u7565\uff08<a href=\"\/zh-hk\/treatment-cancer\/\">\u4e86\u89e3\u4ee3\u8b1d\u816b\u7624\u5b78<\/a>).<\/p>\n<h2 id=\"causes-and-risk-factors-of-head-and-neck-cancer-head-and-neck-carcinoma\">\u982d\u9838\u764c\u7684\u75c5\u56e0\u8207\u98a8\u96aa\u56e0\u7d20<\/h2>\n<h3 id=\"genetic-factors\">\u907a\u50b3\u56e0\u7d20<\/h3>\n<p>\u907a\u50b3\u5b78\u986f\u8457\u5f71\u97ff\u982d\u9838\u764c\u7684\u6613\u611f\u6027\u3002\u4e86\u89e3 TP53\u3001EGFR \u64f4\u589e\u7b49\u907a\u50b3\u7a81\u8b8a\u6216\u5f71\u97ff Notch \u8a0a\u865f\u8def\u5f91\u7684\u7a81\u8b8a\u6709\u52a9\u65bc\u81e8\u5e8a\u6c7a\u7b56\u3002\u4eba\u5011\u8d8a\u4f86\u8d8a\u591a\u5730\u9f13\u52f5\u57fa\u56e0\u7be9\u6aa2\u4f86\u8b58\u5225\u9ad8\u98a8\u96aa\u500b\u9ad4\uff0c\u9019\u4e9b\u500b\u9ad4\u5c07\u5f9e\u6709\u91dd\u5c0d\u6027\u7684\u76e3\u6e2c\u548c\u65e9\u671f\u5e79\u9810\u4e2d\u53d7\u76ca\u3002<\/p>\n<h3 id=\"environmental-and-lifestyle-risks\">\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u98a8\u96aa<\/h3>\n<p>\u5c0d\u982d\u9838\u764c\u81f3\u95dc\u91cd\u8981\u7684\u74b0\u5883\u56e0\u7d20\u5305\u62ec\uff1a<\/p>\n<ul>\n<li><strong>\u7159\u8349\u7528\u9014\uff1a<\/strong> \u6709\u83f8\u83f8\u8349\u548c\u7121\u83f8\u83f8\u8349\u90fd\u6703\u5f15\u5165\u81f4\u764c\u7269\u8cea\uff0c\u5c0e\u81f4\u6301\u7e8c\u523a\u6fc0\u548c DNA \u7a81\u8b8a\u3002<\/li>\n<li><strong>\u98f2\u9152\u91cf\uff1a<\/strong> \u983b\u7e41\u98f2\u9152\u6703\u986f\u8457\u589e\u52a0\u98a8\u96aa\uff0c\u7279\u5225\u662f\u8207\u83f8\u8349\u76f8\u4e92\u4f5c\u7528\u6703\u52a0\u5287\u640d\u5bb3\u3002<\/li>\n<li><strong>\u4eba\u985e\u4e73\u7a81\u75c5\u6bd2 (HPV)\uff1a<\/strong> \u9ad8\u5371\u96aa HPV \u682a\uff08HPV-16 \u548c HPV-18\uff09\u5c0e\u81f4\u5f88\u5927\u4e00\u90e8\u5206\u53e3\u54bd\u764c\u75c5\u4f8b\u3002<\/li>\n<li><strong>\u74b0\u5883\u6c61\u67d3\u7269\uff1a<\/strong> \u63a5\u89f8\u77f3\u68c9\u6216\u5de5\u696d\u5316\u5b78\u7269\u8cea\u7b49\u6c61\u67d3\u7269\u6703\u589e\u52a0\u81f4\u764c\u98a8\u96aa\u3002<\/li>\n<li><strong>\u53e3\u8154\u885b\u751f\u4e0d\u826f\u548c\u71df\u990a\u7f3a\u4e4f\uff1a<\/strong> \u4e0d\u826f\u98f2\u98df\u548c\u53e3\u8154\u885b\u751f\u7fd2\u6163\u5c0e\u81f4\u7684\u6162\u6027\u767c\u708e\u548c\u514d\u75ab\u529b\u4e0b\u964d\u6703\u589e\u52a0\u764c\u75c7\u7684\u6613\u611f\u6027\u3002<\/li>\n<\/ul>\n<h3 id=\"diet-and-metabolic-vulnerabilities\">\u98f2\u98df\u548c\u4ee3\u8b1d\u8106\u5f31\u6027<\/h3>\n<p>\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u4f9d\u8cf4\u6027\u5f15\u5165\u4e86\u53ef\u900f\u904e\u98f2\u98df\u548c\u85e5\u7269\u63aa\u65bd\u5229\u7528\u7684\u8106\u5f31\u6027\u3002\u5927\u7d04 50% \u7684\u764c\u7d30\u80de\u56b4\u91cd\u4f9d\u8cf4\u9ea9\u91af\u80fa\u9178\u9032\u884c\u6838\u82f7\u9178\u5408\u6210\uff0c\u9019\u4f7f\u5f97\u9ea9\u91af\u80fa\u9178\u98e2\u9913\u7b56\u7565\u8b8a\u5f97\u8d8a\u4f86\u8d8a\u53ef\u884c\u3002\u5728 AllCancer\uff0c\u7b56\u7565\u6027\u98f2\u98df\u5e79\u9810\u63aa\u65bd\u91dd\u5c0d\u764c\u75c7\u7684\u71c3\u6599\u4f9d\u8cf4\u4ee5\u53ca\u4ee3\u8b1d\u85e5\u7269\u7642\u6cd5\uff0c\u986f\u8457\u63d0\u9ad8\u50b3\u7d71\u6cbb\u7642\u6548\u679c\u3002<\/p>\n<h3 id=\"asian-specific-risks-and-hong-kong-prevalence\">\u4e9e\u6d32\u7279\u6709\u7684\u98a8\u96aa\u548c\u9999\u6e2f\u7684\u76db\u884c\u7387<\/h3>\n<p>\u4e9e\u6d32\u4eba\u7fa4\u8868\u73fe\u51fa\u5f71\u97ff\u98a8\u96aa\u72c0\u6cc1\u7684\u7279\u5b9a\u907a\u50b3\u50be\u5411\u548c\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\uff1a<\/p>\n<ul>\n<li><strong>\u5480\u56bc\u6ab3\u6994\uff1a<\/strong> \u5728\u4e00\u4e9b\u4e9e\u6d32\u793e\u5340\u5ee3\u6cdb\u50b3\u64ad\uff0c\u589e\u52a0\u4e86\u53e3\u8154\u764c\u7684\u98a8\u96aa\u3002<\/li>\n<li><strong>\u9e7d\u9183\u98df\u54c1\uff1a<\/strong> \u5728\u4e9e\u6d32\u98f2\u98df\u4e2d\u5f88\u5e38\u898b\uff0c\u5df2\u88ab\u8b49\u660e\u8207\u9f3b\u54bd\u764c\u98a8\u96aa\u589e\u52a0\u6709\u95dc\u3002<\/li>\n<li><strong>\u75c5\u6bd2\u6d41\u884c\u7387\uff1a<\/strong> \u4e9e\u6d32\u5730\u5340 HPV \u76f8\u95dc\u764c\u75c7\u7684\u767c\u751f\u7387\u5347\u9ad8\uff0c\u9700\u8981\u7a4d\u6975\u7684\u75ab\u82d7\u63a5\u7a2e\u7b56\u7565\u3002<\/li>\n<\/ul>\n<p>\u9999\u6e2f\u7684\u6578\u64da\u5f37\u8abf\u83f8\u8349\u548c\u9152\u7cbe\u662f\u4e3b\u8981\u56e0\u7d20\uff0c\u7d04\u4f54\u7576\u5730\u75c5\u4f8b\u7684 75%\uff0c\u5f37\u8abf\u4e86\u9810\u9632\u764c\u75c7\u7684\u91cd\u8981\u751f\u6d3b\u65b9\u5f0f\u6539\u8b8a\uff08\u9999\u6e2f\u764c\u75c7\u767b\u8a18\u8655\uff0c2024 \u5e74\uff09\u3002<\/p>\n<h3 id=\"early-detection-and-preventive-strategies\">\u65e9\u671f\u767c\u73fe\u8207\u9810\u9632\u7b56\u7565<\/h3>\n<p>\u9810\u9632\u65b9\u6cd5\u4ecd\u7136\u662f\u982d\u9838\u764c\u7ba1\u7406\u7684\u652f\u67f1\uff1a<\/p>\n<ul>\n<li>\u5e38\u898f\u7259\u79d1\u6216\u9ad4\u6aa2\uff0c\u5305\u62ec\u53e3\u8154\u3001\u5589\u56a8\u548c\u6dcb\u5df4\u7d50\u8a55\u4f30\u3002<\/li>\n<li>\u4fc3\u9032\u6212\u83f8\u548c\u6212\u9152\u8a08\u5283\u3002<\/li>\n<li>\u5e74\u8f15\u65cf\u7fa4\u7684 HPV \u75ab\u82d7\u63a5\u7a2e\u3002<\/li>\n<\/ul>\n<p>\u65e9\u671f\u8b58\u5225\u5f9e\u6839\u672c\u4e0a\u63d0\u9ad8\u6cbb\u7642\u6548\u679c\u4e26\u986f\u8457\u6539\u5584\u60a3\u8005\u9810\u5f8c\uff08<a href=\"\/zh-hk\/our-hospital\/\">\u6709\u95dc\u8a3a\u65b7\u7684\u66f4\u591a\u8cc7\u8a0a\u8acb\u53c3\u898b\u6b64\u8655<\/a>\uff09\u3002\u4e86\u89e3\u60a8\u4eca\u5929\u9762\u81e8\u7684\u98a8\u96aa\u2014\u610f\u8b58\u4ecd\u7136\u662f\u60a8\u6700\u5f37\u5927\u7684\u4fdd\u969c\u3002<\/p>\n<h2 id=\"symptoms-of-head-and-neck-cancer-head-and-neck-carcinoma\">\u982d\u9838\u764c\u7684\u75c7\u72c0<\/h2>\n<p>\u8b58\u5225\u75c7\u72c0 <strong>\u982d\u9838\u764c<\/strong> \u65e9\u671f\u81f3\u95dc\u91cd\u8981\uff0c\u900f\u904e\u53ca\u6642\u8a55\u4f30\u548c\u958b\u59cb\u6cbb\u7642\u53ef\u986f\u8457\u6539\u5584\u9810\u5f8c\u3002\u96d6\u7136\u75c7\u72c0\u53ef\u80fd\u56e0\u816b\u7624\u4f4d\u7f6e\u548c\u5206\u671f\u800c\u7570\uff0c\u4f46\u60a3\u8005\u7d93\u5e38\u51fa\u73fe\u67d0\u4e9b\u5fb5\u5146\u3002<\/p>\n<h3 id=\"common-early-symptoms-stage-1-and-2\">\u5e38\u898b\u7684\u65e9\u671f\u75c7\u72c0\uff08\u7b2c 1 \u671f\u548c\u7b2c 2 \u671f\uff09<\/h3>\n<p>\u5728\u65e9\u671f\u968e\u6bb5\uff08\u7b2c 1-2 \u968e\u6bb5\uff09\uff0c\u75c7\u72c0\u901a\u5e38\u5f88\u5fae\u5999\uff0c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u9838\u90e8\u3001\u53e3\u8154\u6216\u5589\u56a8\u5340\u57df\u51fa\u73fe\u7121\u75db\u6027\u816b\u584a<\/li>\n<li>\u6301\u7e8c\u53e3\u8154\u6216\u5589\u56a8\u75bc\u75db\u8d85\u904e\u5169\u5230\u4e09\u9031<\/li>\n<li>\u541e\u56a5\u56f0\u96e3\u6216\u98df\u7269\u5361\u5728\u5589\u56a8\u7684\u611f\u89ba<\/li>\n<li>\u6301\u7e8c\u8072\u97f3\u6c99\u555e\u6216\u8072\u97f3\u54c1\u8cea\u767c\u751f\u8b8a\u5316<\/li>\n<li>\u4e0d\u660e\u539f\u56e0\u7684\u8033\u6735\u58d3\u75db\u6216\u4e0d\u9069\uff0c\u7121\u660e\u986f\u611f\u67d3<\/li>\n<li>\u53e3\u8154\u6f70\u760d\u5169\u9031\u4e0d\u7652\u5408<\/li>\n<li>\u53e3\u8154\u5167\u51fa\u73fe\u767d\u8272\u6216\u7d05\u8272\u6591\u584a\uff08\u767d\u6591\u6216\u7d05\u6591\uff09<\/li>\n<\/ul>\n<h3 id=\"indications-of-advanced-disease-stages-3-4\">\u665a\u671f\u75be\u75c5\u7684\u6307\u5fb5\uff083-4 \u671f\uff09<\/h3>\n<p>\u96a8\u8457\u75be\u75c5\u9032\u5c55\u5230\u7b2c 3 \u6216\u7b2c 4 \u671f\uff0c\u75c7\u72c0\u8b8a\u5f97\u66f4\u52a0\u660e\u986f\uff0c\u7a81\u986f\u816b\u7624\u751f\u9577\u548c\u5340\u57df\u64f4\u6563\u3002\u665a\u671f\u75c7\u72c0\u901a\u5e38\u8868\u73fe\u70ba\uff1a<\/p>\n<ul>\n<li>\u7531\u65bc\u8f49\u79fb\u6027\u6dcb\u5df4\u7d50\u53d7\u7d2f\uff0c\u9838\u90e8\u51fa\u73fe\u660e\u986f\u816b\u8139\u6216\u5927\u816b\u584a<\/li>\n<li>\u6301\u7e8c\u75bc\u75db\u653e\u5c04\u81f3\u982d\u90e8\u3001\u9838\u90e8\u6216\u80a9\u90e8\uff0c\u4e14\u8207\u7c21\u55ae\u539f\u56e0\u4e0d\u4e00\u81f4<\/li>\n<li>\u8207\u816b\u7624\u584a\u6c23\u9053\u963b\u585e\u76f8\u95dc\u7684\u547c\u5438\u56f0\u96e3<\/li>\n<li>\u9ad4\u91cd\u610f\u5916\u986f\u8457\u6e1b\u8f15\uff08\u4e00\u500b\u6708\u9ad4\u91cd&gt;5%\uff09<\/li>\n<li>\u6c92\u6709\u4efb\u4f55\u523a\u6fc0\u7684\u60c5\u6cc1\u4e0b\u9f3b\u5b50\u6216\u5634\u5df4\u6301\u7e8c\u6d41\u8840<\/li>\n<li>\u8207\u8166\u795e\u7d93\u53d7\u7d2f\u76f8\u95dc\u7684\u81c9\u90e8\u5340\u57df\u9ebb\u6728\u6216\u9ebb\u75fa<\/li>\n<li>\u56e0\u6c23\u9053\u6216\u98df\u9053\u53d7\u640d\u800c\u983b\u7e41\u767c\u751f\u7a92\u606f<\/li>\n<\/ul>\n<p>\u9019\u4e9b\u75c7\u72c0\u53cd\u6620\u4e86\u816b\u7624\u751f\u7269\u5b78\u548c\u9ad8\u7d1a\u7d44\u7e54\u4fb5\u8972\uff0c\u56e0\u6b64\u53ca\u6642\u5c31\u91ab\u81f3\u95dc\u91cd\u8981\u3002\u5fc5\u9808\u7dca\u6025\u8a55\u4f30\u8d85\u904e 2-3 \u9031\u7684\u6301\u7e8c\u75c7\u72c0\uff0c\u4ee5\u6700\u5927\u9650\u5ea6\u5730\u63d0\u9ad8\u6cbb\u7642\u6548\u679c\u548c\u751f\u5b58\u524d\u666f\u3002\u900f\u904e\u6211\u5011\u7684\u7d9c\u5408\u4e86\u89e3\u66f4\u591a <a href=\"\/zh-hk\/our-hospital\/\">\u8a3a\u65b7\u8a55\u4f30\u9801\u9762<\/a>.<\/p>\n<h2 id=\"stages-of-head-and-neck-cancer-head-and-neck-carcinoma-and-survival-rates\">\u982d\u9838\u764c\u7684\u5206\u671f\u8207\u5b58\u6d3b\u7387<\/h2>\n<p>\u7684\u968e\u6bb5 <strong>\u982d\u9838\u764c<\/strong> \u8a3a\u65b7\u986f\u8457\u5f71\u97ff\u6cbb\u7642\u548c\u9810\u5f8c\u3002\u8a73\u7d30\u7684\u5206\u671f\u6709\u5229\u65bc\u500b\u5225\u5316\u6cbb\u7642\u7b56\u7565\uff0c\u65e8\u5728\u6700\u5927\u9650\u5ea6\u5730\u63d0\u9ad8\u751f\u5b58\u7387\u548c\u529f\u80fd\u4fdd\u7559\u3002<\/p>\n<h3 id=\"stage-1-head-and-neck-cancer-head-and-neck-carcinoma\">\u7b2c 1 \u671f \u2013 \u982d\u9838\u764c<\/h3>\n<p>\u5728\u7b2c 1 \u671f\uff0c\u982d\u9838\u764c\u6d89\u53ca\u5c40\u90e8\u816b\u7624\uff0c\u901a\u5e38\u5c0f\u65bc 2 \u5398\u7c73\uff0c\u4e0d\u6d89\u53ca\u6dcb\u5df4\u7d50\u3002\u9019\u500b\u65e9\u671f\u968e\u6bb5\u63d0\u4f9b\u4e86\u826f\u597d\u7684\u9810\u5f8c\u548c\u591a\u7a2e\u6cbb\u7642\u9078\u64c7\uff1a<\/p>\n<ul>\n<li>\u6d89\u53ca\u5fae\u5275\u6216\u50b3\u7d71\u5207\u9664\u816b\u7624\u584a\u7684\u624b\u8853<\/li>\n<li>\u6a19\u9776\u653e\u5c04\u6cbb\u7642\u4f5c\u70ba\u4e3b\u8981\u6cbb\u7642\u65b9\u5f0f\u9078\u64c7<\/li>\n<li>\u6839\u64da\u6700\u8fd1\u7684\u4e9e\u592a\u816b\u7624\u5b78\u5831\u544a\uff08\u9999\u6e2f\u764c\u75c7\u767b\u8a18\u8655\uff0c2024 \u5e74\uff09\uff0c\u5b58\u6d3b\u7387\u6975\u9ad8\uff0c5 \u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 85-95%<\/li>\n<\/ul>\n<h3 id=\"stage-2-head-and-neck-cancer-head-and-neck-carcinoma\">\u7b2c 2 \u671f \u2013 \u982d\u9838\u764c<\/h3>\n<p>2 \u671f\u986f\u793a\u816b\u7624\u7a0d\u5927\uff082-4 \u516c\u5206\uff09\uff0c\u53ef\u80fd\u8f15\u5fae\u6d89\u53ca\u9644\u8fd1\u6dcb\u5df4\u7d50\u3002\u900f\u904e\u53ca\u6642\u7684\u6cbb\u7642\u5e79\u9810\uff0c\u9810\u5f8c\u4ecd\u7136\u826f\u597d\uff1a<\/p>\n<ul>\n<li>\u624b\u8853\u901a\u5e38\u6d89\u53ca\u6709\u9650\u7684\u9838\u90e8\u6e05\u6383\u8853<\/li>\n<li>\u653e\u5c04\u6cbb\u7642\u901a\u5e38\u5728\u624b\u8853\u5f8c\u76f8\u7e7c\u6216\u540c\u6642\u806f\u5408\u9032\u884c<\/li>\n<li>\u5b58\u6d3b\u7387\u4ecd\u7136\u4ee4\u4eba\u653e\u5fc3\uff0c\u76ee\u524d\u7684\u7d71\u8a08\u6578\u64da\u986f\u793a\uff0c\u9999\u6e2f\u53ca\u9031\u908a\u4e9e\u6d32\u570b\u5bb6\u7684 5 \u5e74\u5b58\u6d3b\u7387\u70ba 70-85%<\/li>\n<\/ul>\n<h3 id=\"stage-3-head-and-neck-cancer-head-and-neck-carcinoma\">\u7b2c 3 \u671f \u2013 \u982d\u9838\u764c<\/h3>\n<p>\u7b2c 3 \u671f\u7a81\u986f\u816b\u7624\u9032\u4e00\u6b65\u751f\u9577\u8d85\u51fa\u7dca\u9130\u5340\u57df\uff0c\u4e26\u4f34\u96a8\u660e\u986f\u7684\u6dcb\u5df4\u7d50\u53d7\u7d2f\u6216\u816b\u7624\u5c3a\u5bf8\u8f03\u5927\uff08&gt; 4\u516c\u5206\uff09\u3002\u6b64\u968e\u6bb5\u7684\u6cbb\u7642\u65b9\u6848\u8b8a\u70ba\u591a\u6a21\u5f0f\uff0c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u624b\u8853\u5207\u9664\u4e26\u4f34\u96a8\u9838\u90e8\u6e05\u6383\u8853\u4ee5\u53bb\u9664\u8f49\u79fb\u6dcb\u5df4\u7d50<\/li>\n<li>\u5408\u4f75\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\u53ef\u986f\u8457\u964d\u4f4e\u5fa9\u767c\u98a8\u96aa<\/li>\n<li>\u6700\u4f73\u7d50\u679c\u9700\u8981\u7a4d\u6975\u7684\u591a\u5c08\u696d\u7ba1\u7406\u7b56\u7565<\/li>\n<li>\u7576\u4ee3\u5340\u57df\u6578\u64da\u986f\u793a 50-70% \u7684 5 \u5e74\u5b58\u6d3b\u7387\u5f37\u8abf\u9700\u8981\u53ca\u6642\u3001\u5168\u9762\u7684\u6cbb\u7642<\/li>\n<\/ul>\n<h3 id=\"stage-4-head-and-neck-cancer-head-and-neck-carcinoma\">\u7b2c 4 \u671f \u2013 \u982d\u9838\u764c<\/h3>\n<p>\u7b2c 4 \u671f\u4ee3\u8868\u665a\u671f\u75be\u75c5\uff0c\u6d89\u53ca\u4fb5\u5165\u66f4\u6df1\u7684\u7d44\u7e54\u6216\u9060\u7aef\u8f49\u79fb\uff08\u80ba\u3001\u809d\u6216\u9aa8\uff09\uff0c\u5448\u73fe\u8907\u96dc\u7684\u81e8\u5e8a\u60c5\u6cc1\u3002\u6b64\u968e\u6bb5\u7684\u6a19\u6e96\u6cbb\u7642\u65b9\u6cd5\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u7d9c\u5408\u591a\u5b78\u79d1\u8b77\u7406\uff0c\u5305\u62ec\u7a4d\u6975\u5316\u7642\u3001\u514d\u75ab\u6cbb\u7642\u548c\u653e\u5c04\u6cbb\u7642<\/li>\n<li>\u624b\u8853\u7684\u4e3b\u8981\u76ee\u7684\u662f\u7de9\u89e3\u963b\u585e\u6027\u6216\u75bc\u75db\u75c5\u4f8b\u7684\u8212\u9069\u611f\u6216\u5b89\u5be7\u7642\u8b77\u4ee5\u53ca\u6539\u5584\u751f\u6d3b\u8cea\u7d20<\/li>\n<li>\u9f13\u52f5\u53c3\u8207\u751f\u7269\u6a19\u9776\u6cbb\u7642\u548c\u5148\u9032\u7cfb\u7d71\u6cbb\u7642\u7684\u81e8\u5e8a\u8a66\u9a57<\/li>\n<li>\u751f\u5b58\u4f30\u8a08\u8868\u660e\u8b8a\u7570\u6027\uff1b\u7136\u800c\uff0c\u9810\u8a08\u8a72\u5730\u5340\u7684\u4e2d\u4f4d 3 \u5e74\u751f\u5b58\u7387\u7d04\u70ba 25-30%\uff0c\u9019\u5f37\u8abf\u4e86\u5c0d\u65e8\u5728\u9577\u671f\u7ba1\u7406\u764c\u75c7\u7684\u6cbb\u7642\u5275\u65b0\u7684\u91cd\u8981\u8003\u616e<\/li>\n<\/ul>\n<p>\u8afe\u8c9d\u723e\u734e\u652f\u6301\u7684\u7814\u7a76\u7684\u6700\u65b0\u5275\u65b0\uff0c\u4f8b\u5982\u91dd\u5c0d\u816b\u7624\u7279\u7570\u6027\u6f0f\u6d1e\u7684\u4ee3\u8b1d\u7642\u6cd5\uff0c\u70ba\u6f5b\u5728\u8f49\u5316\u5148\u9032\u6280\u8853\u63d0\u4f9b\u4e86\u9014\u5f91 <strong>\u982d\u9838\u764c<\/strong> \u9032\u5165\u53ef\u63a7\u5236\u7684\u6162\u6027\u75c5\u3002\u9019\u8207 AllCancer \u7684 2025 \u5e74\u9858\u666f\u4e00\u81f4\uff0c\u5373\u70ba\u5168\u7403\u6578\u767e\u842c\u4eba\u6539\u8b8a\u816b\u7624\u5b78\u8b77\u7406\u3002\u63a2\u7d22\u6211\u5011\u5c08\u7528\u7684\u9032\u4e00\u6b65\u9032\u6b65 <a href=\"\/zh-hk\/treatment-cancer\/\">\u764c\u75c7\u6cbb\u7642\u9078\u64c7\u9801\u9762<\/a>.<\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-head-and-neck-cancer-head-and-neck-carc\">\u982d\u9838\u764c\u50b3\u7d71\u7642\u6cd5\u7684\u9650\u5236<\/h2>\n<h3 id=\"challenges-associated-with-chemotherapy-in-head-and-neck-cancer-head-and-neck-ca\">\u982d\u9838\u764c\u5316\u7642\u76f8\u95dc\u7684\u6311\u6230<\/h3>\n<p>\u5316\u7642\u4ecd\u7136\u662f\u8a3a\u65b7\u70ba\u982d\u9838\u764c\u60a3\u8005\u7684\u5e38\u898b\u6cbb\u7642\u9078\u64c7\u3002\u5118\u7ba1\u9019\u7a2e\u7642\u6cd5\u7121\u8655\u4e0d\u5728\uff0c\u4f46\u5b83\u5177\u6709\u986f\u8457\u7684\u5c40\u9650\u6027\u548c\u526f\u4f5c\u7528\uff0c\u6703\u640d\u5bb3\u60a3\u8005\u7684\u751f\u6d3b\u8cea\u7d20\uff0c\u7279\u5225\u662f\u5728\u6d89\u53ca\u665a\u671f\u764c\u75c7\u7684\u60c5\u6cc1\u4e0b\u3002<\/p>\n<p>\u570d\u7e5e\u5316\u7642\u7684\u4e3b\u8981\u64d4\u6182\u4e4b\u4e00\u662f\u5176\u76f8\u7576\u5927\u7684\u6bd2\u6027\u3002\u6839\u64da 2023 \u5e74\u767c\u8868\u5728\u300aJAMA Oncology\u300b\u4e0a\u7684\u6700\u65b0\u7814\u7a76\uff0c\u7d04 <strong>78% \u7684\u60a3\u8005\u51fa\u73fe\u9aa8\u9ad3\u6291\u5236<\/strong>\uff0c\u5c0e\u81f4\u8840\u7d05\u7d20\u6c34\u5e73\u964d\u4f4e\u4e26\u986f\u8457\u589e\u52a0\u611f\u67d3\u98a8\u96aa\u3002\u6b64\u5916\uff0c\u5316\u7642\u9084\u5e36\u6709 <strong>23% \u7684\u5fc3\u81df\u6bd2\u6027\u98a8\u96aa<\/strong>\uff0c\u9019\u662f\u4e00\u7a2e\u56b4\u91cd\u7684\u4f75\u767c\u75c7\uff0c\u53ef\u80fd\u6703\u5f71\u97ff\u5fc3\u81df\u529f\u80fd\u4e26\u52a0\u5287\u5176\u4ed6\u73fe\u6709\u7684\u91ab\u7642\u72c0\u6cc1\uff0c\u7279\u5225\u662f\u8207\u5fc3\u8840\u7ba1\u75be\u75c5\u7a81\u51fa\u7684\u9999\u6e2f\u548c\u4e9e\u6d32\u6709\u95dc\u3002<\/p>\n<p>\u5728\u63a5\u53d7\u5316\u7642\u7684\u60a3\u8005\u4e2d\u7d93\u5e38\u89c0\u5bdf\u5230\u7684\u5176\u4ed6\u526f\u4f5c\u7528\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u6162\u6027\u75b2\u52de\u5f71\u97ff\u60a3\u8005\u7684\u529f\u80fd\u548c\u60c5\u7dd2\u5065\u5eb7\u3002<\/li>\n<li>\u6301\u7e8c\u7684\u5641\u5fc3\u548c\u5614\u5410\u56b4\u91cd\u5f71\u97ff\u98f2\u98df\u651d\u53d6\u3002<\/li>\n<li>\u9ecf\u819c\u640d\u50b7\u5c0e\u81f4\u53e3\u8154\u6f70\u760d\u75bc\u75db\u548c\u541e\u56a5\u56f0\u96e3\u3002<\/li>\n<li>\u5316\u7642\u5f15\u8d77\u7684\u5468\u908a\u795e\u7d93\u75c5\u8b8a\uff0c\u964d\u4f4e\u8eab\u9ad4\u529f\u80fd\u98a8\u96aa\u3002<\/li>\n<\/ul>\n<p>\u56e0\u6b64\uff0c\u9019\u7a2e\u7642\u6cd5\u7684\u7d2f\u7a4d\u526f\u4f5c\u7528\u5f80\u5f80\u6703\u9650\u5236\u60a3\u8005\u7684\u8010\u53d7\u6027\uff0c\u4f7f\u5f97\u5b8c\u6210\u9810\u5b9a\u7684\u6cbb\u7642\u8a08\u756b\u8b8a\u5f97\u56f0\u96e3\uff0c\u4e26\u53ef\u80fd\u964d\u4f4e\u6cbb\u7642\u6548\u679c\u3002<\/p>\n<h3 id=\"radiation-therapy-complications-in-head-and-neck-cancer-head-and-neck-carcinoma\">\u982d\u9838\u764c\u7684\u653e\u5c04\u6cbb\u7642\u4f75\u767c\u75c7<\/h3>\n<p>\u653e\u5c04\u6cbb\u7642\u662f\u53e6\u4e00\u7a2e\u7d93\u5e38\u7528\u65bc\u6cbb\u7642\u982d\u9838\u764c\u7684\u57fa\u77f3\u6cbb\u7642\u65b9\u6cd5\u3002\u7136\u800c\uff0c\u8f3b\u5c04\u4e5f\u5e36\u4f86\u4e86\u76f8\u7576\u5927\u7684\u7f3a\u9ede\uff0c\u7279\u5225\u662f\u5c40\u90e8\u7d44\u7e54\u640d\u50b7\u548c\u660e\u986f\u7684\u60a3\u8005\u4e0d\u9069\u3002<\/p>\n<p>\u6b64\u985e\u764c\u75c7\u7684\u653e\u5c04\u76f8\u95dc\u554f\u984c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u56b4\u91cd\u7684\u9ecf\u819c\u708e\uff0c\u5c0e\u81f4\u9032\u98df\u3001\u541e\u56a5\u548c\u8aaa\u8a71\u56f0\u96e3\u3002<\/li>\n<li>\u7259\u9f52\u4f75\u767c\u75c7\uff0c\u5982\u86c0\u7259\u3001\u7259\u9f66\u840e\u7e2e\u548c\u4e0b\u984e\u9aa8\u640d\u50b7\u3002<\/li>\n<li>\u53e3\u4e7e\u75c7\uff08\u53e3\u4e7e\uff09\u986f\u8457\u964d\u4f4e\u751f\u6d3b\u8cea\u7d20\u4e26\u5f71\u97ff\u71df\u990a\u651d\u53d6\u3002<\/li>\n<li>\u7e96\u7dad\u5316\u548c\u75a4\u75d5\u589e\u52a0\u5c0e\u81f4\u9838\u90e8\u548c\u80a9\u90e8\u6d3b\u52d5\u53d7\u9650\u3002<\/li>\n<\/ul>\n<p>\u7531\u65bc\u9019\u4e9b\u56b4\u91cd\u7684\u4f75\u767c\u75c7\uff0c\u653e\u5c04\u6cbb\u7642\u7121\u610f\u4e2d\u964d\u4f4e\u4e86\u60a3\u8005\u7684\u6574\u9ad4\u4f9d\u5f9e\u6027\u548c\u6eff\u610f\u5ea6\u3002\u6b64\u5916\uff0c\u91cd\u8907\u7684\u653e\u5c04\u6cbb\u7642\u6703\u986f\u8457\u589e\u52a0\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa\uff0c\u6709\u6642\u9ad8\u9054 <strong>\u8207\u672a\u7d93\u6cbb\u7642\u7684\u500b\u9ad4\u76f8\u6bd4\uff0c\u63d0\u9ad8 300%<\/strong> \uff08\u300a\u7f8e\u570b\u91ab\u5b78\u6703\u96dc\u8a8c\u816b\u7624\u5b78\u300b\uff0c2023 \u5e74\uff09\u3002\u56e0\u6b64\uff0c\u5fc5\u9808\u8a8d\u771f\u6b0a\u8861\u653e\u5c04\u6cbb\u7642\u7684\u9577\u671f\u98a8\u96aa\u8207\u6cbb\u7642\u6548\u679c\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8001\u5e74\u60a3\u8005\u548c\u60a3\u6709\u9999\u6e2f\u4eba\u53e3\u80cc\u666f\u4e0b\u5e38\u898b\u4f75\u767c\u75c7\u7684\u60a3\u8005\u3002<\/p>\n<h3 id=\"surgical-interventions-risk-and-quality-of-life-in-head-and-neck-cancer-head-and\">\u624b\u8853\u4ecb\u5165\uff1a\u982d\u9838\u764c\u7684\u98a8\u96aa\u548c\u751f\u6d3b\u8cea\u7d20<\/h3>\n<p>\u982d\u9838\u764c\u7684\u624b\u8853\u6cbb\u7642\u901a\u5e38\u6703\u5e36\u4f86\u8a31\u591a\u91cd\u5927\u98a8\u96aa\u3002\u5118\u7ba1\u5916\u79d1\u624b\u8853\u53d6\u5f97\u4e86\u9032\u6b65\uff0c\u4f46\u6b64\u985e\u4fb5\u5165\u6027\u5e79\u9810\u63aa\u65bd\u7684\u4f75\u767c\u75c7\u4ecd\u7136\u5c45\u9ad8\u4e0d\u4e0b\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8001\u5e74\u60a3\u8005\u6216\u4e9e\u6d32\u4eba\u7fa4\u4e2d\u5178\u578b\u7684\u5065\u5eb7\u8106\u5f31\u4eba\u7fa4\u3002<\/p>\n<p>\u5e38\u898b\u7684\u624b\u8853\u98a8\u96aa\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u589e\u52a0\u611f\u67d3\u7684\u53ef\u80fd\u6027\uff0c\u4f7f\u8853\u5f8c\u6062\u5fa9\u8b8a\u5f97\u8907\u96dc\u3002<\/li>\n<li>\u56b4\u91cd\u7684\u6bc0\u5bb9\u548c\u7f8e\u611f\u554f\u984c\u5f71\u97ff\u81ea\u5c0a\u548c\u5fc3\u7406\u5065\u5eb7\u3002<\/li>\n<li>\u541e\u56a5\u3001\u8a00\u8a9e\u6216\u547c\u5438\u529f\u80fd\u6c38\u4e45\u53d7\u640d\uff0c\u5c0d\u751f\u6d3b\u8cea\u7d20\u7522\u751f\u4e0d\u5229\u5f71\u97ff\u3002<\/li>\n<li>\u5ef6\u9577\u7684\u4f4f\u9662\u6642\u9593\u548c\u5bc6\u96c6\u7684\u5584\u5f8c\u8b77\u7406\u8981\u6c42\uff0c\u5c0e\u81f4\u60a3\u8005\u548c\u7167\u8b77\u8005\u7684\u8ca0\u64d4\u589e\u52a0\u3002<\/li>\n<\/ul>\n<p>\u6b64\u5916\uff0c\u624b\u8853\u6cbb\u7642\u7684\u4fb5\u5165\u6027\u901a\u5e38\u6703\u5c0e\u81f4\u6162\u6027\u554f\u984c\uff0c\u4f8b\u5982\u75bc\u75db\u3001\u4e0d\u9069\u548c\u751f\u6d3b\u65b9\u5f0f\u7684\u91cd\u5927\u6539\u8b8a\uff0c\u5f9e\u800c\u6975\u5927\u5730\u5f71\u97ff\u60c5\u7dd2\u5e73\u8861\u548c\u793e\u4ea4\u3002<\/p>\n<h3 id=\"limited-efficacy-in-metastatic-and-advanced-stage-head-and-neck-cancer-head-and-\">\u5c0d\u8f49\u79fb\u6027\u548c\u665a\u671f\u982d\u9838\u764c\u7684\u7642\u6548\u6709\u9650<\/h3>\n<p>\u6240\u6709\u982d\u9838\u764c\u50b3\u7d71\u6cbb\u7642\u65b9\u6cd5\u5171\u6709\u7684\u4e00\u500b\u57fa\u672c\u7f3a\u9ede\u662f\uff0c\u4e00\u65e6\u75be\u75c5\u9032\u5c55\u6216\u8f49\u79fb\uff0c\u5176\u6f5b\u5728\u7642\u6548\u660e\u986f\u6709\u9650\u3002\u7814\u7a76\u8868\u660e\uff0c\u5316\u7642\u3001\u653e\u5c04\u6cbb\u7642\u751a\u81f3\u7a4d\u6975\u624b\u8853\u65b9\u6cd5\u7684\u7642\u6548\u5728\u75be\u75c5\u665a\u671f\u6703\u6025\u5287\u4e0b\u964d\u3002<\/p>\n<p>\u76ee\u524d\u7684\u81e8\u5e8a\u6578\u64da\u8868\u660e\uff0c\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR) \u8f03\u4f4e\uff0c\u7d04\u70ba <strong>\u8f49\u79fb\u6027\u982d\u9838\u764c\u7684\u767c\u751f\u7387\u4f4e\u65bc 21%<\/strong> \u63a5\u53d7\u50b3\u7d71\u6cbb\u7642\u7684\u60a3\u8005\u3002\u5982\u6b64\u6709\u9650\u7684\u6210\u529f\u7387\u51f8\u986f\u4e86\u5c0d\u66f4\u5148\u9032\u3001\u66f4\u6709\u6548\u3001\u66f4\u6709\u91dd\u5c0d\u6027\u7684\u6cbb\u7642\u65b9\u5f0f\u7684\u9700\u6c42\uff0c\u9019\u4e9b\u6cbb\u7642\u65b9\u5f0f\u5c08\u9580\u8a2d\u8a08\u7528\u65bc\u6709\u6548\u5730\u5c0d\u6297\u764c\u75c7\u589e\u6b96\u548c\u6d88\u9664\u8f49\u79fb\u6027\u751f\u9577\u3002<\/p>\n<h3 id=\"metabolic-resistance-mechanisms-in-head-and-neck-cancer-head-and-neck-carcinoma\">\u982d\u9838\u764c\u7684\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236<\/h3>\n<p>\u5c0e\u81f4\u50b3\u7d71\u7642\u6cd5\u6548\u679c\u4e0d\u4f73\u7684\u4e00\u500b\u95dc\u9375\u969c\u7919\u662f\u4ee3\u8b1d\u62b5\u6297\uff0c\u9019\u662f\u982d\u9838\u764c\u7d30\u80de\u986f\u8457\u8868\u73fe\u51fa\u7684\u986f\u8457\u7684\u9069\u61c9\u6027\u6a5f\u5236\u3002\u9019\u4e9b\u764c\u7d30\u80de\u4e3b\u8981\u53d7\u7cd6\u89e3\u4f5c\u7528\u589e\u52a0\uff08\u83ef\u4f2f\u683c\u6548\u61c9\uff09\u7b49\u4ee3\u8b1d\u6539\u8b8a\u7684\u9a45\u52d5\uff0c\u900f\u904e\u986f\u8457\u589e\u5f37\u5176\u4fee\u5fa9\u80fd\u529b\uff0c\u5feb\u901f\u9069\u61c9\u5316\u7642\u6216\u653e\u5c04\u6cbb\u7642\u5f15\u8d77\u7684 DNA \u640d\u50b7\u3002<\/p>\n<p>\u76ee\u524d\u7684\u7814\u7a76\u5f37\u8abf\u4e86\u4e00\u500b\u5f15\u4eba\u6ce8\u76ee\u7684 <strong>\u63a5\u53d7\u653e\u5c04\u6cbb\u7642\u6216\u5316\u5b78\u6cbb\u7642\u7684\u764c\u7d30\u80de\u4e2d DNA \u4fee\u5fa9\u9176\u6d3b\u6027\u589e\u52a0 400%<\/strong>\u3002\u9019\u7a2e\u7368\u7279\u7684\u4ee3\u8b1d\u9069\u61c9\u73fe\u50cf\u6709\u6548\u5730\u4e2d\u548c\u4e86\u6cbb\u7642\u5f15\u8d77\u7684\u7d30\u80de\u6bd2\u6027\uff0c\u4f7f\u60e1\u6027\u7d30\u80de\u7372\u5f97\u7a4d\u6975\u7684\u6cbb\u7642\u6297\u85e5\u6027\u3002<\/p>\n<p>\u9019\u7a2e\u9069\u61c9\u6027\u4ee3\u8b1d\u8b8a\u5316\u6975\u5927\u5730\u963b\u7919\u4e86\u6cbb\u7642\u7684\u6210\u529f\u7387\uff0c\u4e26\u5f37\u70c8\u8868\u660e\u672a\u4f86\u6210\u529f\u7684\u6cbb\u7642\u65b9\u5f0f\u5fc5\u9808\u7d50\u5408\u660e\u78ba\u91dd\u5c0d\u9019\u4e9b\u8106\u5f31\u6027\u7684\u5275\u65b0\u4ee3\u8b1d\u6a19\u9776\u7642\u6cd5\uff0c\u5c24\u5176\u8207\u5289\u570b\u9f8d\u6559\u6388\u548c\u674e\u570b\u83ef\u535a\u58eb\u7b49\u8457\u540d\u7814\u7a76\u4eba\u54e1\u5021\u5c0e\u7684\u79d1\u5b78\u65b9\u6cd5\u7522\u751f\u5171\u9cf4\u3002<\/p>\n<p>\u7e3d\u9ad4\u800c\u8a00\uff0c\u9451\u65bc\u9019\u4e9b\u6df1\u523b\u7684\u6cbb\u7642\u5c40\u9650\u6027\uff0c\u982d\u9838\u764c\u60a3\u8005\u5c0d\u65b0\u7642\u6cd5\u548c\u7d9c\u5408\u6cbb\u7642\u65b9\u6cd5\u4ecd\u7136\u5b58\u5728\u5927\u91cf\u800c\u7dca\u8feb\u7684\u91ab\u7642\u9700\u6c42\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u5730\u5340\u7368\u7279\u7684\u793e\u6703\u6587\u5316\u548c\u6d41\u884c\u75c5\u5b78\u80cc\u666f\u4e0b\u3002<\/p>\n<h2>4D \u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u76844D \u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u555f\u52d5\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u30022024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u8cea\u7d20\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u555f\u52d5<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7e3d\u7d50<\/strong><\/h2>\n<p>4D \u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u53c3\u8003\u6587\u737b<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u7acb\u5373\u9810\u7d04<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p class=\"ac-blog-disclaimer\"><em>\u91ab\u7642\u514d\u8cac\u8072\u660e\uff1a\u672c\u6587\u50c5\u7528\u65bc\u4e00\u822c\u6559\u80b2\uff0c\u4e0d\u80fd\u53d6\u4ee3\u5408\u683c\u81e8\u5e8a\u91ab\u751f\u7684\u5efa\u8b70\u3002\u6cbb\u7642\u6c7a\u5b9a\u61c9\u57fa\u65bc\u500b\u4eba\u7684\u8a3a\u65b7\u3001\u5206\u671f\u3001\u75c5\u7406\u548c\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002\u5982\u679c\u60a8\u767c\u73fe\u6301\u7e8c\u6216\u4ee4\u4eba\u64d4\u6182\u7684\u75c7\u72c0\uff0c\u8acb\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u3002<\/em><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u982d\u9838\u764c\u662f\u6307\u8d77\u6e90\u65bc\u982d\u9838\u90e8\u5340\u57df\u7d44\u7e54\u6216\u5668\u5b98\u7684\u4e00\u7d44\u764c\u75c7\uff0c\u5305\u62ec\u53e3\u8154\u2026<\/p>","protected":false},"featured_media":226,"menu_order":38,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-360","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/360","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"version-history":[{"count":1,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/360\/revisions"}],"predecessor-version":[{"id":500,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/360\/revisions\/500"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/media\/226"}],"wp:attachment":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/media?parent=360"}],"curies":[{"name":"\u53ef\u6fd5\u6027\u7c89\u5291","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}