{"id":380,"date":"2026-06-26T09:00:00","date_gmt":"2026-06-26T09:00:00","guid":{"rendered":"https:\/\/cntumour.com\/cancer\/salivary-gland-cancer-salivary-gland-carcinoma-cancer\/"},"modified":"2026-10-29T15:53:22","modified_gmt":"2026-10-29T15:53:22","slug":"salivary-gland-cancer-salivary-gland-carcinoma-cancer","status":"publish","type":"cancer_type","link":"https:\/\/cntumour.com\/zh-hk\/cancer\/salivary-gland-cancer-salivary-gland-carcinoma-cancer\/","title":{"rendered":"\u553e\u6db2\u817a\u764c"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u553e\u6db2\u817a\u764c\u662f\u6307\u767c\u751f\u5728\u553e\u6db2\u817a\u7d44\u7e54\u5167\u7684\u60e1\u6027\u816b\u7624\uff0c\u4e3b\u8981\u898b\u65bc\u4e09\u500b\u4e3b\u8981\u914d\u5c0d\u817a\u9ad4\uff0d\u816e\u817a\u3001\u4e0b\u9837\u817a\u548c\u820c\u4e0b\u817a\u3002\u9019\u4e9b\u817a\u9ad4\u5728\u6d88\u5316\u548c\u53e3\u8154\u5065\u5eb7\u4e2d\u767c\u63ee\u8457\u81f3\u95dc\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u7522\u751f\u541e\u56a5\u3001\u6d88\u5316\u548c\u4fdd\u8b77\u53e3\u8154\u9ecf\u819c\u514d\u53d7\u611f\u67d3\u6240\u5fc5\u9700\u7684\u553e\u6db2\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-salivary-gland-cancer-salivary-gland-carcinoma\">\u4ec0\u9ebc\u662f\u553e\u6db2\u817a\u764c\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-salivary-gland-cancer-salivary-gland-carcinoma\">\u553e\u6db2\u817a\u764c\u7684\u75c5\u56e0\u548c\u98a8\u96aa\u56e0\u7d20<\/a><\/li>\n<li><a href=\"#symptoms-of-salivary-gland-cancer-salivary-gland-carcinoma\">\u553e\u6db2\u817a\u764c\u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-salivary-gland-cancer-salivary-gland-carcinoma-and-survival-rates\">\u553e\u6db2\u817a\u764c\u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-salivary-gland-cancer-salivary-gland-ca\">\u553e\u6db2\u817a\u764c\u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-salivary-gland-cancer-salivary-gland-carcinoma\">\u4ec0\u9ebc\u662f\u553e\u6db2\u817a\u764c\uff1f<\/h2>\n<p>\u5728\u751f\u7269\u5b78\u5c64\u9762\u4e0a\uff0c\u764c\u7d30\u80de\u8868\u73fe\u51fa\u7368\u7279\u7684\u4ee3\u8b1d\u884c\u70ba\uff0c\u5c07\u5b83\u5011\u8207\u6b63\u5e38\u7d30\u80de\u660e\u986f\u5340\u5206\u958b\u4f86\u3002\u7279\u5225\u7a81\u51fa\u7684\u662f\u201c\u74e6\u723e\u5821\u6548\u61c9\u201d\uff0c\u5373\u5373\u4f7f\u5728\u5bcc\u6c27\u689d\u4ef6\u4e0b\uff0c\u764c\u7d30\u80de\u4ee3\u8b1d\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u4e5f\u6bd4\u5178\u578b\u5065\u5eb7\u7d30\u80de\u5feb\u7d04 200 \u500d\u3002\u553e\u6db2\u817a\u764c\u5177\u6709\u9019\u7a2e\u986f\u8457\u7684\u4ee3\u8b1d\u7279\u5fb5\uff0c\u9019\u4f7f\u5f97\u5b83\u5011\u5c0d\u5275\u65b0\u7684\u4ee3\u8b1d\u6a19\u9776\u6cbb\u7642\u7279\u5225\u654f\u611f\u3002<\/p>\n<h3 id=\"salivary-gland-cancer-salivary-gland-carcinoma-prevalence-and-epidemiology\">\u553e\u6db2\u817a\u764c\uff0d\u76db\u884c\u7387\u548c\u6d41\u884c\u75c5\u5b78<\/h3>\n<p>\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u553e\u6db2\u817a\u764c\u76f8\u5c0d\u7f55\u898b\uff0c\u6839\u64da\u4e16\u754c\u885b\u751f\u7d44\u7e54 (WHO) 2024 \u5e74\u7684\u6578\u64da\uff0c\u553e\u6db2\u817a\u764c\u4f54\u6240\u6709\u982d\u9838\u90e8\u60e1\u6027\u816b\u7624\u7684\u8fd1 6%\u3002\u5168\u7403\u6bcf\u5e74\u6bcf 10 \u842c\u4eba\u4e2d\u7d04\u6709 5 \u4f8b\u88ab\u8a3a\u65b7\u51fa\u4f86\u3002\u5118\u7ba1\u6574\u9ad4\u767c\u75c5\u7387\u8f03\u4f4e\uff0c\u4f46\u7279\u5b9a\u65cf\u7fa4\u7684\u98a8\u96aa\u8f03\u9ad8\uff0c\u5c24\u5176\u662f\u7531\u65bc\u7368\u7279\u7684\u907a\u50b3\u3001\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\uff0c\u5c0d\u9999\u6e2f\u7b49\u5730\u5340\u7684\u4e9e\u6d32\u4eba\u7fa4\u7522\u751f\u4e86\u5f71\u97ff\u3002<\/p>\n<ul>\n<li>\u76db\u884c\u7387\uff1a\u5168\u7403\u6bcf 10 \u842c\u4eba\u4e2d\u7d04\u6709 5 \u4f8b\uff08\u4e16\u754c\u885b\u751f\u7d44\u7e54\uff0c2024 \u5e74\uff09\u3002<\/li>\n<li>50-80 \u6b72\u6210\u5e74\u4eba\u7684\u767c\u751f\u7387\u7565\u6709\u4e0a\u5347\u3002<\/li>\n<li>\u8207\u5973\u6027\u76f8\u6bd4\uff0c\u7537\u6027\u7565\u4f54\u512a\u52e2\u3002<\/li>\n<\/ul>\n<p>\u5728\u4e9e\u6d32\u4eba\u7fa4\u4e2d\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\uff0c\u98f2\u98df\u7fd2\u6163\u548c\u5730\u7406\u56e0\u7d20\u9020\u6210\u4e86\u7368\u7279\u7684\u8106\u5f31\u6027\u3002\u57ce\u5e02\u5316\u548c\u76f8\u95dc\u7684\u6c61\u67d3\u66b4\u9732\u53ef\u80fd\u6703\u52a0\u5287\u98a8\u96aa\u6c34\u6e96\u3002\u60a3\u8005\u5e38\u5e38\u6703\u7d93\u6b77\u56b4\u91cd\u7684\u60c5\u7dd2\u548c\u5fc3\u7406\u640d\u5931\uff0c\u540c\u6642\u4e5f\u6703\u51fa\u73fe\u816b\u8139\u3001\u4e0d\u9069\u548c\u53e3\u8154\u529f\u80fd\u4e0b\u964d\u7b49\u8eab\u9ad4\u75c7\u72c0\u3002<\/p>\n<h3 id=\"physical-and-emotional-impact-of-salivary-gland-cancer\">\u553e\u6db2\u817a\u764c\u5c0d\u8eab\u9ad4\u548c\u60c5\u611f\u7684\u5f71\u97ff<\/h3>\n<p>\u88ab\u8a3a\u65b7\u60a3\u6709\u553e\u6db2\u817a\u764c\u7684\u500b\u9ad4\u53ef\u80fd\u9762\u81e8\u6df1\u9060\u7684\u8eab\u9ad4\u5f71\u97ff\uff0c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u4e0b\u5df4\u3001\u9838\u90e8\u6216\u53e3\u8154\u5468\u570d\u816b\u8139\u6216\u816b\u584a<\/li>\n<li>\u541e\u56a5\u56f0\u96e3\u6216\u5f35\u5927\u5634\u56f0\u96e3<\/li>\n<li>\u81c9\u90e8\u9ebb\u6728\u3001\u523a\u75db\u6216\u808c\u8089\u7121\u529b<\/li>\n<li>\u5f71\u97ff\u65e5\u5e38\u6d3b\u52d5\u7684\u6301\u7e8c\u75bc\u75db\u6216\u4e0d\u9069<\/li>\n<\/ul>\n<p>\u5728\u60c5\u611f\u4e0a\uff0c\u60a3\u8005\u9762\u81e8\u56b4\u91cd\u7684\u7126\u616e\u548c\u58d3\u529b\u3002\u5b64\u7acb\u611f\u3001\u81ea\u6211\u5f62\u8c61\u6539\u8b8a\u4ee5\u53ca\u5c0d\u764c\u75c7\u9032\u5c55\u7684\u64d4\u6182\u5f88\u5e38\u898b\u3002\u5728 AllCancer\uff0c\u6211\u5011\u5168\u5fc3\u5168\u610f\u5730\u540c\u60c5\u6b64\u985e\u7d93\u6b77\uff0c\u4e26\u5805\u5b9a\u81f4\u529b\u65bc\u4ee5\u60a3\u8005\u70ba\u4e2d\u5fc3\u7684\u8b77\u7406\u3002\u65e9\u671f\u6aa2\u6e2c\u4ecd\u7136\u662f\u95dc\u9375\uff0c\u53ef\u4ee5\u986f\u8457\u6539\u5584\u9810\u5f8c\uff0c\u4e26\u8b93\u60a3\u8005\u7372\u5f97\u8207\u8afe\u8c9d\u723e\u734e\u7372\u734e\u7814\u7a76\u76f8\u7d50\u5408\u7684\u524d\u6cbf\u7642\u6cd5\uff0c\u9019\u4e9b\u7642\u6cd5\u7531\u674e\u570b\u83ef\u535a\u58eb\u548c\u5289\u570b\u9f8d\u6559\u6388\u7b49\u5168\u7403\u77e5\u540d\u5c08\u5bb6\u9818\u5c0e\u3002<\/p>\n<h3 id=\"understanding-cancer-metabolism-spotlight-on-glucose-dependency\">\u4e86\u89e3\u764c\u75c7\u4ee3\u8b1d\uff0d\u805a\u7126\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027<\/h3>\n<p>\u5373\u4f7f\u5728\u6c27\u6c23\u5145\u8db3\u7684\u60c5\u6cc1\u4e0b\uff0c\u764c\u7d30\u80de\u4e5f\u4e3b\u8981\u8868\u73fe\u51fa\u80fd\u91cf\u4ee3\u8b1d\u9014\u5f91\u7684\u6539\u8b8a\uff0c\u4e3b\u8981\u662f\u7cd6\u89e3\u4f5c\u7528\u2014\u2014\u9019\u500b\u6a19\u8a8c\u5728\u79d1\u5b78\u4e0a\u88ab\u7a31\u70ba\u74e6\u4f2f\u683c\u6548\u61c9\u3002\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b Gregg Semenza \u535a\u58eb\u5ee3\u6cdb\u63cf\u8ff0\u4e86\u9019\u7a2e\u4ee3\u8b1d\u7279\u5fb5\uff0c\u63d0\u4f9b\u4e86\u4e00\u7a2e\u76f4\u63a5\u91dd\u5c0d\u8461\u8404\u7cd6\u651d\u53d6\u548c\u5229\u7528\u7684\u65b0\u6cbb\u7642\u89d2\u5ea6\u3002\u553e\u6db2\u817a\u764c\u53cd\u8986\u8868\u73fe\u51fa\u8461\u8404\u7cd6\u6d88\u8017\u7387\u5347\u9ad8\u3002<\/p>\n<p>\u5229\u7528\u5091\u51fa\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u5148\u9a45\u674e\u570b\u83ef\u535a\u58eb\u7684\u898b\u89e3\uff0c\u6211\u5011\u5728 AllCancer \u7684\u65b9\u6cd5\u7d50\u5408\u4e86\u65e8\u5728\u7cfb\u7d71\u5730\u5229\u7528\u9019\u4e9b\u7368\u7279\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\u7684\u7642\u6cd5\uff0c\u5f9e\u800c\u91cd\u5851\u4e9e\u6d32\u553e\u6db2\u817a\u764c\u7684\u8b77\u7406\u548c\u7d50\u679c\u3002\u4e86\u89e3\u6211\u5011\u5728\u764c\u75c7\u751f\u7269\u5b78\u65b9\u9762\u7684\u7a81\u7834\u6027\u7814\u7a76 <a href=\"\/zh-hk\/treatment-cancer\/\">\u9019\u88e1<\/a>.<\/p>\n<h2 id=\"causes-and-risk-factors-of-salivary-gland-cancer-salivary-gland-carcinoma\">\u553e\u6db2\u817a\u764c\u7684\u75c5\u56e0\u548c\u98a8\u96aa\u56e0\u7d20<\/h2>\n<p>\u96d6\u7136\u5f15\u767c\u553e\u6db2\u817a\u764c\u7684\u78ba\u5207\u6a5f\u5236\u4ecd\u7136\u591a\u7a2e\u591a\u6a23\uff0c\u4f46\u7814\u7a76\u4eba\u54e1\u5df2\u7d93\u78ba\u5b9a\u4e86\u8207\u907a\u50b3\u3001\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u76f8\u95dc\u7684\u95dc\u9375\u98a8\u96aa\u56e0\u7d20\u986f\u8457\u76f8\u95dc\u3002<\/p>\n<h3 id=\"genetic-factors-their-role-in-salivary-gland-cancer\">\u907a\u50b3\u56e0\u7d20\u53ca\u5176\u5728\u553e\u6db2\u817a\u764c\u4e2d\u7684\u4f5c\u7528<\/h3>\n<p>\u5e7e\u7a2e\u907a\u50b3\u6a19\u8a18\u6709\u52a9\u65bc\u589e\u52a0\u553e\u6db2\u817a\u60e1\u6027\u816b\u7624\u7684\u6613\u611f\u6027\uff1a<\/p>\n<ul>\n<li>\u57fa\u56e0\u7a81\u8b8a\uff08\u4f8b\u5982 TP53\u3001NOTCH1\uff09\u7279\u5225\u5e38\u898b\u65bc\u553e\u6db2\u817a\u764c\u3002<\/li>\n<li>\u67d0\u4e9b\u907a\u50b3\u6027\u907a\u50b3\u7d9c\u5408\u75c7\uff08\u4f8b\u5982\uff0c\u7531 TP53 \u57fa\u56e0\u7a81\u8b8a\u5f15\u8d77\u7684 Li-Fraumeni \u7d9c\u5408\u75c7\uff0c\u6703\u5927\u5927\u589e\u52a0\u98a8\u96aa\uff09\u3002<\/li>\n<\/ul>\n<h3 id=\"environmental-risks-in-hong-kong-and-asia\">\u9999\u6e2f\u53ca\u4e9e\u6d32\u7684\u74b0\u5883\u98a8\u96aa<\/h3>\n<p>\u9577\u671f\u63a5\u89f8\u7576\u5730\u74b0\u5883\u81f4\u764c\u7269\u53ef\u80fd\u6703\u589e\u52a0\u553e\u6db2\u817a\u764c\u7684\u767c\u751f\u7387\uff0c\u9019\u7a2e\u81f4\u764c\u7269\u5728\u9999\u6e2f\u7b49\u4eba\u53e3\u7a20\u5bc6\u7684\u57ce\u5e02\u4e2d\u5fc3\u66f4\u70ba\u5e38\u898b\u3002\u516c\u8a8d\u7684\u74b0\u5883\u81f4\u764c\u7269\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u9577\u6642\u9593\u66b4\u9732\u65bc\u8f3b\u5c04\uff08\u96fb\u96e2\u8f3b\u5c04\uff09\u3002<\/li>\n<li>\u8077\u696d\u63a5\u89f8\u4e8c\u6c27\u5316\u77fd\u7c89\u5875\u3001\u93b3\u5316\u5408\u7269\u6216\u67d0\u4e9b\u5316\u5b78\u6eb6\u5291\u3002<\/li>\n<li>\u9ad8\u5ea6\u5de5\u696d\u5316\u7684\u4e9e\u6d32\u57ce\u5e02\u74b0\u5883\u4e2d\u5e38\u898b\u7684\u74b0\u5883\u7a7a\u6c23\u6c61\u67d3\u7269\u3002<\/li>\n<\/ul>\n<h3 id=\"lifestyle-risk-factors-associated-with-salivary-cancer\">\u8207\u553e\u6db2\u817a\u764c\u76f8\u95dc\u7684\u751f\u6d3b\u65b9\u5f0f\u98a8\u96aa\u56e0\u7d20<\/h3>\n<p>\u751f\u6d3b\u65b9\u5f0f\u7684\u9078\u64c7\u53ef\u4ee5\u986f\u8457\u5f71\u97ff\u500b\u9ad4\u7f79\u60a3\u553e\u6db2\u817a\u764c\u7684\u98a8\u96aa\u3002\u5177\u9ad4\u4f86\u8aaa\uff0c\u56e0\u7d20\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u83f8\u8349\u6d88\u8cbb\uff08\u6709\u83f8\u83f8\u8349\u548c\u7121\u83f8\u83f8\u8349\u8b8a\u7a2e\uff09<\/li>\n<li>\u98f2\u9152\uff0c\u7279\u5225\u662f\u8207\u83f8\u8349\u7d50\u5408\u6642\uff0c\u6703\u986f\u8457\u589e\u52a0\u81f4\u764c\u98a8\u96aa\u3002<\/li>\n<li>\u4e0d\u826f\u7684\u98f2\u98df\u7fd2\u6163\uff0c\u901a\u5e38\u662f\u52a0\u5de5\u98df\u54c1\u548c\u7cd6\u542b\u91cf\u9ad8\u7684\u98f2\u98df\uff0c\u53ef\u80fd\u9593\u63a5\u4fc3\u9032\u764c\u75c7\u4ee3\u8b1d\u3002<\/li>\n<li>\u53e3\u8154\u885b\u751f\u4e0d\u826f\u548c\u53e3\u8154\u6162\u6027\u767c\u708e\u72c0\u614b\u3002<\/li>\n<\/ul>\n<h3 id=\"metabolic-vulnerabilities-targeting-cancer-cell-glucose-and-glutamine-dependenci\">\u4ee3\u8b1d\u8106\u5f31\u6027\uff1a\u91dd\u5c0d\u764c\u7d30\u80de\u8461\u8404\u7cd6\u548c\u9ea9\u91af\u80fa\u9178\u4f9d\u8cf4\u6027<\/h3>\n<p>\u73fe\u5728\uff0c\u5275\u65b0\u7642\u6cd5\u7b56\u7565\u6027\u5730\u91dd\u5c0d\u764c\u7d30\u80de\u5c0d\u8461\u8404\u7cd6\u548c\u9ea9\u91af\u80fa\u9178\u4ee3\u8b1d\u9014\u5f91\u7684\u56b4\u91cd\u4f9d\u8cf4\u3002\u8fd1\u4e00\u534a\u7684\u764c\u7d30\u80de\u5f88\u5927\u7a0b\u5ea6\u4e0a\u4f9d\u8cf4\u9ea9\u91af\u80fa\u9178\u4f86\u5408\u6210\u95dc\u9375\u751f\u7269\u5206\u5b50\uff0c\u5305\u62ec\u6838\u82f7\u9178\u3002\u56e0\u6b64\uff0c\u91cf\u8eab\u5b9a\u5236\u7684\u4ee3\u8b1d\u7642\u6cd5\u6210\u70ba\u553e\u6db2\u817a\u764c\u7684\u4e00\u500b\u975e\u5e38\u6709\u524d\u9014\u7684\u7b56\u7565\u3002<\/p>\n<p>\u900f\u904e\u907a\u50b3\u548c\u4ee3\u8b1d\u7be9\u6aa2\u53ca\u65e9\u8b58\u5225\u9019\u4e9b\u98a8\u96aa\u56e0\u7d20\u53ef\u4ee5\u5c0d\u9810\u5f8c\u7522\u751f\u986f\u8457\u7684\u6b63\u9762\u5f71\u97ff\u3002\u56e0\u6b64\uff0c\u9ad8\u98a8\u96aa\u65cf\u7fa4\u7684\u9810\u9632\u6027\u7be9\u6aa2\u4ecd\u7136\u81f3\u95dc\u91cd\u8981\u3002\u63a2\u7d22 AllCancer Diagnostics \u63d0\u4f9b\u7684\u9769\u547d\u6027\u8a3a\u65b7\u9078\u9805 <a href=\"\/zh-hk\/our-hospital\/\">\u9019\u88e1<\/a>.<\/p>\n<p>\u5982\u9700\u500b\u4eba\u8aee\u8a62\u6216\u8a0e\u8ad6\u5229\u7528\u5275\u65b0\u4ee3\u8b1d\u6a19\u9776\u7642\u6cd5\u7684\u6cbb\u7642\u53ef\u80fd\u6027\uff0c\u8acb\u7acb\u5373\u806f\u7d61 AllCancer\u3002\u6211\u5011\u8207\u8457\u540d\u7684\u816b\u7624\u5b78\u9818\u5c0e\u8005\u3001\u4ee5\u60a3\u8005\u70ba\u4e2d\u5fc3\u7684\u5bcc\u6709\u540c\u60c5\u5fc3\u7684\u8b77\u7406\u4ee5\u53ca\u8afe\u8c9d\u723e\u734e\u652f\u6301\u7684\u7814\u7a76\u4e00\u8d77\uff0c\u81f4\u529b\u65bc\u6539\u8b8a\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u793e\u5340\u7684\u553e\u6db2\u817a\u764c\u6cbb\u7642\u548c\u60a3\u8005\u6cbb\u7642\u7d50\u679c\u3002<\/p>\n<h2 id=\"symptoms-of-salivary-gland-cancer-salivary-gland-carcinoma\">\u553e\u6db2\u817a\u764c\u7684\u75c7\u72c0<\/h2>\n<p>\u8b58\u5225\u65e9\u671f\u8de1\u8c61 <strong>\u553e\u6db2\u817a\u764c<\/strong> \u53ef\u4ee5\u986f\u8457\u63d0\u9ad8\u6cbb\u7642\u6548\u679c\u3002\u5f88\u591a\u6642\u5019\uff0c\u75c7\u72c0\u6700\u521d\u53ef\u80fd\u770b\u8d77\u4f86\u5f88\u5fae\u5999\uff0c\u56e0\u6b64\u88ab\u5ffd\u8996\u6216\u8aa4\u8a8d\u70ba\u662f\u4e0d\u592a\u56b4\u91cd\u7684\u60c5\u6cc1\u3002\u56e0\u6b64\uff0c\u4e86\u89e3\u660e\u78ba\u7684\u75c7\u72c0\u5c0d\u65bc\u65e9\u671f\u8a3a\u65b7\u548c\u4ecb\u5165\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<h3 id=\"common-early-symptoms\">\u5e38\u898b\u7684\u65e9\u671f\u75c7\u72c0<\/h3>\n<ul>\n<li>\u4e0b\u5df4\u3001\u9838\u90e8\u6216\u53e3\u8154\u5340\u57df\u9644\u8fd1\u51fa\u73fe\u816b\u584a\u6216\u816b\u8139<\/li>\n<li>\u81c9\u90e8\u808c\u8089\u9ebb\u6728\u6216\u7121\u529b\uff0c\u5c24\u5176\u662f\u4e00\u5074<\/li>\n<li>\u81c9\u90e8\u3001\u53e3\u8154\u6216\u9838\u90e8\u75bc\u75db\u6216\u58d3\u75db<\/li>\n<li>\u541e\u56a5\u56f0\u96e3\u6216\u5f35\u5927\u5634\u56f0\u96e3<\/li>\n<li>\u8072\u97f3\u660e\u986f\u8b8a\u5316\u6216\u6e05\u6670\u8aaa\u8a71\u56f0\u96e3<\/li>\n<li>\u53e3\u8154\u5340\u57df\u6301\u7e8c\u75bc\u75db<\/li>\n<li>\u8033\u9053\u6709\u7570\u5e38\u5206\u6ccc\u7269\u6216\u6392\u6c34<\/li>\n<li>\u53d7\u5f71\u97ff\u5340\u57df\u9644\u8fd1\u6dcb\u5df4\u7d50\u816b\u5927<\/li>\n<\/ul>\n<h3 id=\"symptoms-variation-by-cancer-stage\">\u4e0d\u540c\u764c\u75c7\u5206\u671f\u7684\u75c7\u72c0\u8b8a\u5316<\/h3>\n<h4>\u65e9\u671f\u968e\u6bb5<\/h4>\n<p>\u5728\u65e9\u671f\u553e\u6db2\u817a\u764c\u4e2d\uff0c\u75c7\u72c0\u53ef\u80fd\u5f88\u5c0f\u6216\u975e\u7279\u7570\u6027\uff0c\u901a\u5e38\u8868\u73fe\u70ba\u7121\u75db\u816b\u8139\u6216\u816b\u584a\uff0c\u5e38\u88ab\u8aa4\u8a8d\u70ba\u662f\u611f\u67d3\u6216\u56ca\u816b\u7b49\u826f\u6027\u75be\u75c5\u3002\u65e9\u671f\u8b58\u5225\u96d6\u7136\u5177\u6709\u6311\u6230\u6027\uff0c\u4f46\u53ef\u4ee5\u986f\u8457\u6539\u5584\u9810\u5f8c\u3002<\/p>\n<h4>\u9ad8\u7d1a\u968e\u6bb5<\/h4>\n<p>\u665a\u671f\u764c\u75c7\u901a\u5e38\u8868\u73fe\u51fa\u66f4\u5f37\u70c8\u7684\u660e\u986f\u75c7\u72c0\uff0c\u4f8b\u5982\uff1a<\/p>\n<ul>\n<li>\u900f\u904e\u81c9\u90e8\u6216\u9838\u90e8\u795e\u7d93\u653e\u5c04\u7684\u5287\u70c8\u75bc\u75db<\/li>\n<li>\u8a00\u8a9e\u548c\u5480\u56bc\u5b58\u5728\u56b4\u91cd\u56f0\u96e3<\/li>\n<li>\u984f\u9762\u795e\u7d93\u9ebb\u75fa\u6216\u56b4\u91cd\u9ebb\u6728\u610f\u5473\u8457\u795e\u7d93\u53d7\u4fb5\u72af<\/li>\n<li>\u7121\u6cd5\u7652\u5408\u7684\u53ef\u898b\u7621\u53e3\u6216\u6f70\u760d<\/li>\n<li>\u53e3\u8154\u6216\u5589\u56a8\u6301\u7e8c\u51fa\u8840<\/li>\n<li>\u7531\u65bc\u98f2\u98df\u4e0d\u7576\u5c0e\u81f4\u9ad4\u91cd\u660e\u986f\u6e1b\u8f15\u3001\u75b2\u52de\u548c\u71df\u990a\u7f3a\u4e4f<\/li>\n<\/ul>\n<p>\u9019\u4e9b\u75c7\u72c0\u53cd\u6620\u4e86\u764c\u75c7\u7684\u4fb5\u8972\u6027\uff0c\u5f71\u97ff\u5927\u5c0f\u795e\u7d93\u7e96\u7dad\u548c\u7d44\u7e54\uff0c\u7834\u58de\u6b63\u5e38\u529f\u80fd\u4e26\u56b4\u91cd\u640d\u5bb3\u751f\u6d3b\u8cea\u7d20\u3002\u4e86\u89e3\u9019\u4e9b\u751f\u7269\u5b78\u75c7\u72c0\u5f37\u8abf\u4e86\u7acb\u5373\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u7684\u7dca\u8feb\u6027\u3002<\/p>\n<p><strong>\u65e9\u671f\u884c\u52d5\u81f3\u95dc\u91cd\u8981\u3002<\/strong> \u5982\u679c\u60a8\u6216\u60a8\u8a8d\u8b58\u7684\u4eba\u51fa\u73fe\u4efb\u4f55\u9019\u4e9b\u75c7\u72c0\uff0c\u7279\u5225\u662f\u6301\u7e8c\u5b58\u5728\uff0c\u7acb\u5373\u5b89\u6392\u91ab\u7642\u8aee\u8a62\u53ef\u4ee5\u5927\u5927\u63d0\u9ad8\u8a3a\u65b7\u6e96\u78ba\u6027\u548c\u6cbb\u7642\u7d50\u679c\u3002 <a href=\"\/zh-hk\/our-hospital\/\">\u5728\u9019\u88e1\u63a2\u7d22\u8a3a\u65b7\u9078\u9805<\/a>.<\/p>\n<h2 id=\"stages-of-salivary-gland-cancer-salivary-gland-carcinoma-and-survival-rates\">\u553e\u6db2\u817a\u764c\u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/h2>\n<p>\u4e86\u89e3\u5206\u671f\u53ef\u4ee5\u63d0\u4f9b\u75be\u75c5\u9032\u5c55\u7684\u91cd\u8981\u898b\u89e3\uff0c\u4e26\u5e6b\u52a9\u81e8\u5e8a\u91ab\u751f\u78ba\u5b9a\u6700\u4f73\u6cbb\u7642\u7b56\u7565\u3002\u4ee5\u4e0b\u7e3d\u7d50\u4e86\u5404\u500b\u968e\u6bb5\u548c\u5404\u81ea\u7684\u9810\u5f8c\uff0c\u7279\u5225\u91dd\u5c0d\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u4eba\u53e3\u7d71\u8a08\u3002<\/p>\n<h3 id=\"stage-1-salivary-gland-cancer-salivary-gland-carcinoma\">\u7b2c 1 \u671f \u2013 \u553e\u6db2\u817a\u764c<\/h3>\n<p>\u5728\u7b2c 1 \u671f\uff0c\u816b\u7624\u4ecd\u7136\u5c40\u9650\u65bc\u5c40\u90e8\uff0c\u76f4\u5f91\u901a\u5e38\u5c0f\u65bc 2 \u516c\u5206\u3002<\/p>\n<ul>\n<li><strong>\u7279\u5fb5\uff1a<\/strong> \u975e\u4fb5\u5165\u6027\uff0c\u816b\u7624\u584a\u6709\u9650\uff0c\u5c40\u90e8\u5c40\u9650\uff0c\u7121\u8f49\u79fb\u3002<\/li>\n<li><strong>\u6cbb\u7642\u65b9\u6848\uff1a<\/strong> \u5c40\u90e8\u624b\u8853\u5207\u9664\uff0c\u6709\u6642\u96a8\u5f8c\u9032\u884c\u6a19\u9776\u653e\u5c04\u6cbb\u7642\u4ee5\u589e\u5f37\u7642\u6548\u3002<\/li>\n<li><strong>\u5b58\u6d3b\u7387\uff1a<\/strong> \u9810\u5f8c\u9ad8\uff0d\u6839\u64da\u6700\u8fd1\u7684\u9999\u6e2f\u91ab\u7642\u5831\u544a\u548c\u764c\u75c7\u767b\u8a18\u8655 (2024)\uff0c\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 90-95%\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-2-salivary-gland-cancer-salivary-gland-carcinoma\">\u7b2c 2 \u671f \u2013 \u553e\u6db2\u817a\u764c<\/h3>\n<p>\u7b2c 2 \u671f\u63cf\u8ff0\u4e86\u8d85\u51fa\u521d\u59cb\u5b9a\u4f4d\u7684\u751f\u9577\uff0c\u53ef\u80fd\u5f71\u97ff\u9130\u8fd1\u7d44\u7e54\uff0c\u4f46\u6c92\u6709\u5ee3\u6cdb\u7684\u6dcb\u5df4\u53d7\u7d2f\u3002<\/p>\n<ul>\n<li><strong>\u7279\u5fb5\uff1a<\/strong> \u816b\u7624\u5927\u5c0f\u5728 2-4 \u516c\u5206\u4e4b\u9593\u8b8a\u5316\uff0c\u5468\u570d\u7d44\u7e54\u53ef\u80fd\u5728\u986f\u5fae\u93e1\u4e0b\u53d7\u7d2f\u3002<\/li>\n<li><strong>\u6cbb\u7642\u65b9\u6848\uff1a<\/strong> \u64f4\u5927\u624b\u8853\u5207\u9664\u7bc4\u570d\uff0c\u5305\u62ec\u908a\u7de3\u548c\u53ef\u80fd\u76f8\u95dc\u7684\u6dcb\u5df4\u7d50\uff0c\u4e26\u7d50\u5408\u8f14\u52a9\u653e\u5c04\u6cbb\u7642\uff0c\u4ee5\u76e1\u91cf\u6e1b\u5c11\u5fa9\u767c\u3002<\/li>\n<li><strong>\u5b58\u6d3b\u7387\uff1a<\/strong> \u6709\u5229\u4f46\u9069\u5ea6\u964d\u4f4e\u2014\u2014\u6771\u4e9e\u4eba\u7fa4\u7684\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 70-85%\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-3-salivary-gland-cancer-salivary-gland-carcinoma\">\u7b2c 3 \u671f \u2013 \u553e\u6db2\u817a\u764c<\/h3>\n<p>\u7b2c 3 \u671f\u986f\u793a\u5340\u57df\u9032\u5c55\uff0c\u4f34\u96a8\u660e\u986f\u7684\u6dcb\u5df4\u7d50\u53d7\u7d2f\u548c\u66f4\u6df1\u7684\u7d44\u7e54\u4fb5\u72af\u3002<\/p>\n<ul>\n<li><strong>\u7279\u5fb5\uff1a<\/strong> \u816b\u7624\u8d85\u904e4\u5398\u7c73\uff0c\u660e\u986f\u4fb5\u72af\u9644\u8fd1\u7d50\u69cb\u6216\u6df1\u5c64\u81c9\u90e8\u7d44\u7e54\u5c64\u3002<\/li>\n<li><strong>\u6cbb\u7642\u65b9\u6848\uff1a<\/strong> \u591a\u6a21\u5f0f\u6cbb\u7642\u5305\u62ec\u5ee3\u6cdb\u7684\u624b\u8853\u6cbb\u7642\uff0c\u5305\u62ec\u5fc5\u8981\u6642\u7684\u5207\u9664\u8853\uff0c\u52a0\u4e0a\u7a4d\u6975\u7684\u8853\u5f8c\u653e\u5c04\u6cbb\u7642\u548c\u6f5b\u5728\u7684\u5316\u7642\u65b9\u6848\u3002<\/li>\n<li><strong>\u5b58\u6d3b\u7387\uff1a<\/strong> \u7531\u65bc\u5340\u57df\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 50-70%\uff0c\u9810\u5f8c\u8b8a\u5f97\u5177\u6709\u6311\u6230\u6027\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-4-salivary-gland-cancer-salivary-gland-carcinoma\">\u7b2c 4 \u671f \u2013 \u553e\u6db2\u817a\u764c<\/h3>\n<p>\u5728\u8f49\u79fb\u6216\u5ee3\u6cdb\u50b3\u64ad\u968e\u6bb5\uff0c\u6709\u6548\u7684\u6cbb\u7642\u8b8a\u5f97\u8907\u96dc\uff0c\u9700\u8981\u6574\u9ad4\u7684\u7cfb\u7d71\u6cbb\u7642\u7b56\u7565\u3002<\/p>\n<ul>\n<li><strong>\u7279\u5fb5\uff1a<\/strong> \u9060\u7aef\u5668\u5b98\u8f49\u79fb\uff0c\u901a\u5e38\u5f71\u97ff\u80ba\u3001\u809d\u548c\u9aa8\u9abc\u7cfb\u7d71\u3002\u7531\u65bc\u75be\u75c5\u5ee3\u6cdb\u50b3\u64ad\uff0c\u767c\u75c5\u7387\u5f88\u9ad8\u3002<\/li>\n<li><strong>\u6cbb\u7642\u65b9\u6848\uff1a<\/strong> \u4e3b\u8981\u662f\u5168\u8eab\u5316\u7642\u3001\u6a19\u9776\u751f\u7269\u6cbb\u7642\u548c\u5275\u65b0\u4ee3\u8b1d\u7642\u6cd5\uff08<a href=\"\/zh-hk\/treatment-cancer\/\">\u4f8b\u5982\u6211\u5011\u5148\u9032\u7684 4D \u7642\u6cd5<\/a>\uff09\u5229\u7528\u74e6\u723e\u5821\u6548\u61c9\u548c\u764c\u7d30\u80de\u7684\u9ea9\u91af\u80fa\u9178\u4f9d\u8cf4\u6027\u3002<\/li>\n<li><strong>\u5b58\u6d3b\u7387\uff1a<\/strong> \u9810\u5f8c\u5177\u6709\u6311\u6230\u6027\u2014\u2014\u6839\u64da\u7d9c\u5408\u4e9e\u6d32\u764c\u75c7\u767b\u8a18\u8655\uff0c\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 20-30%\uff1b\u7136\u800c\uff0c\u65e8\u5728\u9577\u671f\u63a7\u5236\u9019\u7a2e\u75be\u75c5\u7684\u65b0\u8208\u7642\u6cd5\u63d0\u4f9b\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u5e0c\u671b\u3002<\/li>\n<\/ul>\n<p>\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5c0d\u764c\u7d30\u80de\u4ee3\u8b1d\u7406\u89e3\u7684\u9032\u6b65\u63d0\u4f9b\u4e86\u4ee4\u4eba\u8208\u596e\u7684\u6cbb\u7642\u9014\u5f91\uff0c\u65e8\u5728\u5c07\u672b\u671f\u75be\u75c5\u8f49\u5316\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75c5\u3002AllCancer \u5230 2025 \u5e74\u7684\u76ee\u6a19\u662f\u78ba\u4fdd\u5305\u62ec\u665a\u671f\u553e\u6db2\u817a\u764c\u5728\u5167\u7684 20 \u7a2e\u764c\u75c7\u6210\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\uff0c\u70ba\u4e9e\u6d32\u5404\u5730\u5ef6\u9577\u9810\u671f\u58fd\u547d\u3001\u63d0\u9ad8\u751f\u6d3b\u8cea\u7d20\u548c\u6539\u5584\u60a3\u8005\u9810\u5f8c\u5e36\u4f86\u5e0c\u671b\u3002<\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-salivary-gland-cancer-salivary-gland-ca\">\u553e\u6db2\u817a\u764c\u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/h2>\n<h3 id=\"overview-of-traditional-treatments\">\u50b3\u7d71\u6cbb\u7642\u6982\u8ff0<\/h3>\n<p>\u553e\u6db2\u817a\u764c\u7684\u50b3\u7d71\u6cbb\u7642\u65b9\u6cd5\uff0c\u5305\u62ec\u624b\u8853\u3001\u653e\u5c04\u7dda\u6cbb\u7642\u548c\u5316\u5b78\u6cbb\u7642\uff0c\u9577\u671f\u4ee5\u4f86\u4e00\u76f4\u662f\u6cbb\u7642\u7684\u7b2c\u4e00\u7dda\u3002\u7136\u800c\uff0c\u5118\u7ba1\u91ab\u5b78\u53d6\u5f97\u4e86\u9032\u6b65\uff0c\u4f46\u6bcf\u7a2e\u6cbb\u7642\u65b9\u6cd5\u90fd\u5b58\u5728\u5f88\u5927\u7684\u5c40\u9650\u6027\uff0c\u5c24\u5176\u662f\u5728\u665a\u671f\u968e\u6bb5\u3002\u4e86\u89e3\u9019\u4e9b\u9650\u5236\u51f8\u986f\u4e86\u5c0d\u5275\u65b0\u89e3\u6c7a\u65b9\u6848\u7684\u8feb\u5207\u9700\u8981\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u60a3\u8005\u7fa4\u9ad4\u4e2d\u3002<\/p>\n<h3 id=\"surgical-limitations-in-salivary-gland-cancer-salivary-gland-carcinoma\">\u553e\u6db2\u817a\u764c\u7684\u624b\u8853\u9650\u5236<\/h3>\n<p>\u624b\u8853\u4ecb\u5165\u662f\u6cbb\u7642\u5c40\u90e8\u816b\u7624\u7684\u4e3b\u8981\u65b9\u6cd5\uff0c\u4f46\u5f80\u5f80\u56e0\u4e00\u4e9b\u56b4\u91cd\u7684\u98a8\u96aa\u548c\u8003\u616e\u56e0\u7d20\u800c\u8b8a\u5f97\u8907\u96dc\uff0c\u4f8b\u5982\uff1a<\/p>\n<ul>\n<li>\u8853\u5f8c\u611f\u67d3\u7387\u5728 5-10% \u4e4b\u9593\uff0c\u901a\u5e38\u6703\u5c0e\u81f4\u4f4f\u9662\u6642\u9593\u5ef6\u9577\u4e26\u589e\u52a0\u60a3\u8005\u767c\u75c5\u7387\u3002<\/li>\n<li>\u7d0420-30%\u7684\u624b\u8853\u75c5\u4f8b\u6709\u795e\u7d93\u640d\u50b7\u98a8\u96aa\uff0c\u5305\u62ec\u984f\u9762\u795e\u7d93\u9ebb\u75fa\uff0c\u9020\u6210\u9577\u671f\u8eab\u9ad4\u6bc0\u5bb9\u548c\u5fc3\u7406\u5275\u50b7\u3002<\/li>\n<li>\u5728\u8907\u96dc\u7684\u816b\u7624\u90e8\u4f4d\u96e3\u4ee5\u9054\u5230\u9670\u6027\u624b\u8853\u5207\u7de3\uff0c\u986f\u8457\u5f71\u97ff\u5fa9\u767c\u7387\u3002<\/li>\n<\/ul>\n<p>\u5728\u9999\u6e2f\uff0c\u7531\u65bc\u60a3\u8005\u4eba\u53e3\u5bc6\u5ea6\u9ad8\u4e14\u5340\u57df\u5167\u53ef\u7528\u7684\u5c08\u696d\u624b\u8853\u57fa\u790e\u8a2d\u65bd\u6709\u9650\uff0c\u624b\u8853\u4ecb\u5165\u9762\u81e8\u984d\u5916\u7684\u8907\u96dc\u6027\u3002<\/p>\n<h3 id=\"toxicity-associated-with-chemotherapy\">\u8207\u5316\u7642\u76f8\u95dc\u7684\u6bd2\u6027<\/h3>\n<p>\u553e\u6db2\u817a\u764c\u7684\u50b3\u7d71\u5316\u7642\uff0c\u5305\u62ec\u9251\u985e\u5316\u5408\u7269\u548c\u84bd\u74b0\u985e\u85e5\u7269\u7b49\u85e5\u7269\uff0c\u8868\u73fe\u51fa\u76f8\u7576\u5927\u7684\u526f\u4f5c\u7528\u548c\u6bd2\u6027\u6c34\u5e73\uff1a<\/p>\n<ul>\n<li>\u7d04 78% \u7684\u60a3\u8005\u6703\u51fa\u73fe\u9aa8\u9ad3\u6291\u5236\uff0c\u589e\u52a0\u8ca7\u8840\u3001\u611f\u67d3\u548c\u51fa\u8840\u6027\u75be\u75c5\u7684\u98a8\u96aa\u3002<\/li>\n<li>\u7d04 23% \u7684\u75c5\u4f8b\u8a18\u9304\u6709\u5fc3\u81df\u6bd2\u6027\uff0c\u5c24\u5176\u662f\u4f7f\u7528\u84bd\u74b0\u985e\u85e5\u7269\u6642\uff0c\u5c0d\u5fc3\u81df\u5065\u5eb7\u548c\u60a3\u8005\u751f\u6d3b\u8cea\u7d20\u69cb\u6210\u9577\u671f\u5a01\u8105\u3002<\/li>\n<li>\u5641\u5fc3\u3001\u5614\u5410\u548c\u80c3\u8178\u9053\u7d0a\u4e82\u56b4\u91cd\u5f71\u97ff\u60a3\u8005\u7684\u71df\u990a\u548c\u6574\u9ad4\u529b\u91cf\uff0c\u800c\u9019\u662f\u5fa9\u5065\u548c\u75be\u75c5\u7ba1\u7406\u7684\u95dc\u9375\u7d44\u6210\u90e8\u5206\u3002<\/li>\n<li>\u5316\u7642\u5f15\u8d77\u7684\u5468\u908a\u795e\u7d93\u75c5\u8b8a\u6703\u5c0d\u7cbe\u7d30\u904b\u52d5\u6280\u80fd\u7522\u751f\u8ca0\u9762\u5f71\u97ff\uff0c\u9650\u5236\u65e5\u5e38\u6d3b\u52d5\u548c\u7368\u7acb\u6027\u3002<\/li>\n<\/ul>\n<p>\u9019\u4e9b\u986f\u8457\u7684\u6bd2\u6027\u986f\u8457\u5f71\u97ff\u60a3\u8005\u5c0d\u6cbb\u7642\u65b9\u6848\u7684\u4f9d\u5f9e\u6027\uff0c\u5c0e\u81f4\u4e0d\u826f\u7d50\u679c\uff0c\u7279\u5225\u662f\u5728\u665a\u671f\u553e\u6db2\u817a\u764c\u968e\u6bb5\u3002<\/p>\n<h3 id=\"radiation-therapy-challenges\">\u653e\u5c04\u6cbb\u7642\u7684\u6311\u6230<\/h3>\n<p>\u653e\u5c04\u6cbb\u7642\u96d6\u7136\u662f\u5e38\u898b\u7684\u8f14\u52a9\u6cbb\u7642\uff0c\u4f46\u4e5f\u9762\u81e8\u986f\u8457\u7684\u6311\u6230\uff0c\u901a\u5e38\u6703\u56b4\u91cd\u5f71\u97ff\u60a3\u8005\u7684\u5065\u5eb7\uff1a<\/p>\n<ul>\n<li>\u5927\u7d04 60-70% \u7684\u63a5\u53d7\u6cbb\u7642\u7684\u500b\u9ad4\u6703\u51fa\u73fe\u7d44\u7e54\u7e96\u7dad\u5316\u3001\u53e3\u4e7e\u75c7\uff08\u53e3\u4e7e\u7d9c\u5408\u75c7\uff09\u548c\u9ecf\u819c\u640d\u50b7\u3002<\/li>\n<li>\u9577\u671f\u4f75\u767c\u75c7\uff0c\u4f8b\u5982\u5473\u89ba\u6539\u8b8a\u548c\u541e\u56a5\u56f0\u96e3\uff0c\u767c\u751f\u983b\u7387\u5f88\u9ad8\uff0c\u4e26\u986f\u8457\u5f71\u97ff\u60a3\u8005\u7684\u71df\u990a\u548c\u751f\u6d3b\u8cea\u7d20\u3002<\/li>\n<li>\u6700\u8fd1\u7684\u300a\u7f8e\u570b\u91ab\u5b78\u6703\u96dc\u8a8c\u816b\u7624\u5b78 2023\u300b\u7814\u7a76\u8868\u660e\uff0c\u7531\u65bc\u8f3b\u5c04\u66b4\u9732\uff0c\u7e7c\u767c\u6027\u764c\u75c7\u7684\u76db\u884c\u7387\u589e\u52a0\uff0c\u8a72\u7814\u7a76\u8868\u660e\uff0c\u8207\u672a\u66b4\u9732\u7684\u500b\u9ad4\u76f8\u6bd4\uff0c\u7d42\u751f\u98a8\u96aa\u589e\u52a0\u9ad8\u9054 300%\u3002<\/li>\n<li>\u75b2\u52de\u4ecd\u7136\u662f\u8fd1 85% \u63a5\u53d7\u653e\u5c04\u6cbb\u7642\u7684\u60a3\u8005\u4e2d\u5e38\u898b\u7684\u4f7f\u4eba\u8870\u5f31\u7684\u75c7\u72c0\uff0c\u963b\u7919\u4e86\u4ed6\u5011\u7684\u65e5\u5e38\u529f\u80fd\u548c\u60c5\u7dd2\u6062\u5fa9\u80fd\u529b\u3002<\/li>\n<\/ul>\n<h3 id=\"low-efficacy-in-advanced-and-metastatic-cases\">\u665a\u671f\u548c\u8f49\u79fb\u6027\u75c5\u4f8b\u7684\u7642\u6548\u8f03\u4f4e<\/h3>\n<p>\u4e5f\u8a31\u553e\u6db2\u817a\u764c\u50b3\u7d71\u7642\u6cd5\u6700\u95dc\u9375\u7684\u5f31\u9ede\u4e4b\u4e00\u662f\u5176\u7642\u6548\u6709\u9650\uff0c\u7279\u5225\u662f\u5728\u665a\u671f\u6216\u8f49\u79fb\u968e\u6bb5\uff1a<\/p>\n<ul>\n<li>2023 \u5e74\u9032\u884c\u7684\u7814\u7a76\u8868\u660e\uff0c\u50c5\u4f7f\u7528\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\u7b49\u50b3\u7d71\u7642\u6cd5\u7684\u8f49\u79fb\u6027\u553e\u6db2\u817a\u764c\u60a3\u8005\u7684\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR) \u4f4e\u65bc 21%\u3002<\/li>\n<li>\u8f49\u79fb\u60a3\u8005\u7684\u751f\u5b58\u7d50\u679c\u4ecd\u7136\u4f4e\u5f97\u4ee4\u4eba\u5931\u671b\uff0c\u901a\u5e38\u7121\u6cd5\u8d85\u904e 40% \u7684\u5e73\u5747 5 \u5e74\u5b58\u6d3b\u7387\u3002<\/li>\n<li>\u8f03\u4f4e\u7684\u7de9\u89e3\u7387\u5c0d\u65bc\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u60a3\u8005\u7fa4\u9ad4\u4f86\u8aaa\u662f\u6bc0\u6ec5\u6027\u7684\uff0c\u7531\u65bc\u8a8d\u8b58\u6709\u9650\u3001\u7be9\u6aa2\u969c\u7919\u548c\u91ab\u7642\u4fdd\u5065\u53ef\u8fd1\u6027\u65b9\u9762\u7684\u6311\u6230\uff0c\u9ad8\u7d1a\u8a3a\u65b7\u901a\u5e38\u6703\u88ab\u5ef6\u9072\u3002<\/li>\n<\/ul>\n<h3 id=\"metabolic-resistance-mechanisms-in-cancer-cells\">\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236<\/h3>\n<p>\u4e00\u500b\u65e5\u76ca\u91cd\u8981\u7684\u969c\u7919\u662f\u553e\u6db2\u817a\u764c\u7d30\u80de\u56fa\u6709\u7684\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236\u7684\u51fa\u73fe\uff1a<\/p>\n<ul>\n<li>\u9019\u4e9b\u7d30\u80de\u8868\u73fe\u51fa\u5c0d\u8461\u8404\u7cd6\u4ee3\u8b1d\u7684\u4f9d\u8cf4\u6027\u589e\u52a0\uff08\u74e6\u4f2f\u683c\u6548\u61c9\uff09\uff0c\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u6bd4\u6b63\u5e38\u7d30\u80de\u9ad8\u7d04 200 \u500d\uff0c\u52a0\u901f\u589e\u6b96\u4e26\u589e\u5f37\u5c0d\u6a19\u6e96\u7d30\u80de\u6bd2\u6027\u7642\u6cd5\u7684\u62b5\u6297\u529b\u3002<\/li>\n<li>\u6700\u8fd1\u7684\u5be6\u9a57\u5ba4\u7814\u7a76\u8868\u660e\uff0c\u9019\u4e9b\u764c\u7d30\u80de\u7684 DNA \u4fee\u5fa9\u9176\u6d3b\u6027\u589e\u52a0\u4e86 400%\uff0c\u5927\u5927\u964d\u4f4e\u4e86\u5b83\u5011\u5c0d\u4f9d\u8cf4 DNA \u640d\u50b7\u4f86\u7834\u58de\u7d30\u80de\u7684\u50b3\u7d71\u7642\u6cd5\u7684\u654f\u611f\u6027\u3002<\/li>\n<li>\u9ea9\u91af\u80fa\u9178\u4f9d\u8cf4\u6027\u589e\u5f37\u548c\u4ee3\u8b1d\u9014\u5f91\u6539\u8b8a\u4e5f\u80fd\u589e\u5f37\u764c\u7d30\u80de\u7684\u5b58\u6d3b\u7387\uff0c\u62b5\u6d88\u6a19\u6e96\u5316\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\u65b9\u6848\u7684\u7642\u6548\u3002<\/li>\n<\/ul>\n<p>\u8a8d\u8b58\u5230\u9019\u4e9b\u751f\u7269\u5b78\u969c\u7919\u80af\u5b9a\u4e86\u958b\u767c\u660e\u78ba\u65e8\u5728\u5229\u7528\u553e\u6db2\u817a\u764c\u7279\u5b9a\u4ee3\u8b1d\u8106\u5f31\u6027\u7684\u7642\u6cd5\u7684\u91cd\u8981\u6027\u3002<\/p>\n<h3 id=\"the-urgent-need-for-innovative-therapies\">\u8feb\u5207\u9700\u8981\u5275\u65b0\u7642\u6cd5<\/h3>\n<p>\u7121\u53ef\u5426\u8a8d\uff0c\u50b3\u7d71\u6cbb\u7642\u4ecb\u5165\u63aa\u65bd\u63d0\u4f9b\u4e86\u65e9\u671f\u75be\u75c5\u7684\u91cd\u8981\u521d\u59cb\u7b56\u7565\u3002\u7136\u800c\uff0c\u5b83\u5011\u7684\u5c40\u9650\u6027\uff0c\u8868\u73fe\u70ba\u56b4\u91cd\u7684\u6bd2\u6027\u3001\u4f7f\u4eba\u8870\u5f31\u7684\u526f\u4f5c\u7528\u3001\u6709\u9650\u7684\u665a\u671f\u7642\u6548\u548c\u6df1\u523b\u7684\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236\uff0c\u66b4\u9732\u4e86\u5c0d\u6297\u553e\u6db2\u817a\u764c\u7684\u76f8\u7576\u5927\u7684\u5f31\u9ede\u3002<\/p>\n<p>\u56e0\u6b64\uff0c\u8feb\u5207\u9700\u8981\u5411\u5275\u65b0\u7684\u6cbb\u7642\u5275\u65b0\u8f49\u578b\uff0c\u91cd\u65b0\u5b9a\u7fa9\u60a3\u8005\u7684\u6cbb\u7642\u7d50\u679c\u548c\u6574\u9ad4\u6eff\u610f\u5ea6\uff0c\u5c24\u5176\u662f\u5728\u9999\u6e2f\u7b49\u4eba\u53e3\u7a20\u5bc6\u7684\u5730\u5340\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u4eba\u53e3\u4e2d\u3002<\/p>\n<h3 id=\"looking-ahead-towards-metabolic-oncology\">\u5c55\u671b\u672a\u4f86\uff1a\u4ee3\u8b1d\u816b\u7624\u5b78<\/h3>\n<p>\u5229\u7528\u8a79\u59c6\u65af\u00b7\u827e\u5229\u68ee\u535a\u58eb\u548c\u683c\u96f7\u683c\u00b7\u585e\u9580\u624e\u6559\u6388\u7b49\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u7684\u7a81\u7834\u6027\u7814\u7a76\u4ee5\u53ca\u674e\u570b\u83ef\u535a\u58eb\u7b49\u4ee3\u8b1d\u816b\u7624\u5b78\u9818\u5c0e\u8005\u7684\u958b\u5275\u6027\u5275\u65b0\uff0c\u89e3\u6c7a\u57fa\u790e\u4ee3\u8b1d\u8106\u5f31\u6027\u63d0\u4f9b\u4e86\u4e00\u500b\u5145\u6eff\u5e0c\u671b\u7684\u672a\u4f86\u3002<\/p>\n<p>\u6700\u7d42\uff0c\u50b3\u7d71\u6cbb\u7642\u9650\u5236\u6240\u5e36\u4f86\u7684\u5371\u6a5f\u5f37\u8abf\uff0c\u5f15\u5165\u500b\u4eba\u5316\u3001\u6709\u91dd\u5c0d\u6027\u548c\u4ee5\u4ee3\u8b1d\u70ba\u91cd\u9ede\u7684\u65b9\u6cd5\u4e0d\u50c5\u662f\u53ef\u53d6\u7684\uff0c\u800c\u4e14\u5c0d\u65bc\u6709\u610f\u7fa9\u5730\u63d0\u9ad8\u60a3\u8005\u58fd\u547d\u548c\u751f\u6d3b\u8cea\u7d20\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<h2>4D \u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u76844D \u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u555f\u52d5\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u30022024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u8cea\u7d20\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u555f\u52d5<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7e3d\u7d50<\/strong><\/h2>\n<p>4D \u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u53c3\u8003\u6587\u737b<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u7acb\u5373\u9810\u7d04<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p 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