{"id":398,"date":"2026-05-21T09:00:00","date_gmt":"2026-05-21T09:00:00","guid":{"rendered":"https:\/\/cntumour.com\/cancer\/islet-cell-tumor-pancreatic-neuroendocrine-tumor-cancer-types\/"},"modified":"2026-10-29T15:53:24","modified_gmt":"2026-10-29T15:53:24","slug":"islet-cell-tumor-pancreatic-neuroendocrine-tumor-cancer-types","status":"publish","type":"cancer_type","link":"https:\/\/cntumour.com\/zh-hk\/cancer\/islet-cell-tumor-pancreatic-neuroendocrine-tumor-cancer-types\/","title":{"rendered":"\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\uff0c\u901a\u5e38\u7e2e\u5beb\u70ba PanNET\uff0c\u662f\u4e00\u7a2e\u7f55\u898b\u7684\u80f0\u81df\u764c\uff0c\u7531\u7522\u751f\u8377\u723e\u8499\u7684\u7d30\u80de\uff08\u7a31\u70ba\u80f0\u5cf6\u7d30\u80de\u6216\u795e\u7d93\u5167\u5206\u6ccc\u7d30\u80de\uff09\u7522\u751f\u3002\u8207\u50b3\u7d71\u7684\u80f0\u81df\u817a\u764c\u4e0d\u540c\uff0c\u9019\u4e9b\u816b\u7624\u901a\u5e38\u8868\u73fe\u51fa\u751f\u9577\u7de9\u6162\uff0c\u4f46\u7531\u65bc\u8377\u723e\u8499\u5206\u6ccc\u7834\u58de\u8eab\u9ad4\u529f\u80fd\uff0c\u53ef\u80fd\u6703\u56b4\u91cd\u5f71\u97ff\u5065\u5eb7\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u4ec0\u9ebc\u662f\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u75c5\u56e0\u548c\u98a8\u96aa\u56e0\u7d20<\/a><\/li>\n<li><a href=\"#symptoms-of-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-islet-cell-tumor-pancreatic-neuroendocrine-tumor-and-survival-rates\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u968e\u6bb5\u548c\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-islet-cell-tumor-pancreatic-neuroendocr\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u4ec0\u9ebc\u662f\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\uff1f<\/h2>\n<h3 id=\"biological-basis-and-metabolic-vulnerabilities\">\u751f\u7269\u5b78\u57fa\u790e\u548c\u4ee3\u8b1d\u8106\u5f31\u6027<\/h3>\n<p>\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\u8d77\u6e90\u65bc\u80f0\u81df\u5167\u8ca0\u8cac\u8abf\u7bc0\u8840\u7cd6\u7684\u5167\u5206\u6ccc\u7d30\u80de\u3002\u5f9e\u6839\u672c\u4e0a\u4f86\u8aaa\uff0c\u9019\u4e9b\u816b\u7624\u8207\u4ee3\u8b1d\u7d0a\u4e82\u5bc6\u5207\u76f8\u95dc\uff0c\u5c24\u5176\u662f\u74e6\u723e\u5821\u6548\u61c9\u3002\u764c\u7d30\u80de\uff0c\u5305\u62ec <strong>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/strong> \u7d30\u80de\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u6025\u5287\u52a0\u5feb\uff0c\u6bd4\u6b63\u5e38\u7d30\u80de\u9ad8 200 \u500d\u3002\u9019\u7a2e\u4ee3\u8b1d\u4f9d\u8cf4\u6027\u652f\u6490\u8457 AllCancer \u6b63\u5728\u9032\u884c\u7684\u7814\u7a76\uff0c\u4ee5\u5229\u7528\u57fa\u65bc\u4ee3\u8b1d\u7684\u5275\u65b0\u7642\u6cd5\u7684\u7368\u7279\u5f31\u9ede\uff0c\u70ba\u53d7\u5f71\u97ff\u7684\u500b\u9ad4\u5e36\u4f86\u65b0\u7684\u5e0c\u671b\u3002<\/p>\n<p>\u5728\u4ee3\u8b1d\u816b\u7624\u5b78\u8457\u540d\u5148\u9a45\u674e\u570b\u83ef\u535a\u58eb\u9818\u5c0e\u4e0b\u9032\u884c\u7684\u5ee3\u6cdb\u958b\u5275\u6027\u7814\u7a76\u4e2d\uff0c\u5229\u7528\u9019\u4e9b\u5f31\u9ede\u7684\u91dd\u5c0d\u6027\u65b9\u6cd5\u53d6\u5f97\u4e86\u986f\u8457\u7684\u6210\u679c\uff0c\u900f\u904e\u300c4D\u7642\u6cd5\u300d\uff08\u91dd\u5c0d\u8461\u8404\u7cd6\u548c\u9ea9\u91af\u80fa\u9178\u4f9d\u8cf4\u7684\u7b56\u7565\u76ee\u6a19\uff09\u6975\u5927\u5730\u6539\u5584\u4e86\u60a3\u8005\u7684\u6cbb\u7642\u6548\u679c\u3002<\/p>\n<h3 id=\"prevalence-and-impact-in-asia-and-hong-kong\">\u4e9e\u6d32\u548c\u9999\u6e2f\u7684\u6d41\u884c\u7387\u548c\u5f71\u97ff<\/h3>\n<p>\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624 (PanNET) \u50c5\u4f54\u6240\u6709\u80f0\u81df\u764c\u7684 7% \u5de6\u53f3\uff0c\u4f46\u5176\u767c\u751f\u7387\u4ecd\u5728\u6301\u7e8c\u4e0a\u5347\u3002\u5728\u4e9e\u6d32\uff0c\u7279\u5225\u662f\u9999\u6e2f\u7b49\u57ce\u5e02\u4e2d\u5fc3\uff0c\u8a3a\u65b7\u7387\u4e0a\u5347\uff0c\u9019\u53ef\u80fd\u662f\u7531\u65bc\u52a0\u5f37\u4e86\u7be9\u6aa2\u548c\u63d0\u9ad8\u4e86\u516c\u773e\u610f\u8b58\u30022024 \u5e74\u5168\u5e74\u7684\u6d41\u884c\u75c5\u5b78\u6578\u64da\u986f\u793a\uff0c\u5149\u662f\u9999\u6e2f\u6bcf\u5e74\u5c31\u767c\u73fe\u7d04 1,200 \u4f8b\u65b0\u7684 PanNET \u75c5\u4f8b\u3002<\/p>\n<p>\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u5289\u570b\u9f8d\u6559\u6388\u7684\u7814\u7a76\u5f37\u8abf\u4e86\u95dc\u9375\u7684\u4eba\u53e3\u5b78\u898b\u89e3\uff1a<\/p>\n<ul>\n<li>\u5178\u578b\u8a3a\u65b7\u5e74\u9f61\u7bc4\u570d\uff1a40-60\u6b72<\/li>\n<li>\u4e0d\u540c\u6027\u5225\u7684\u98a8\u96aa\u5e73\u7b49<\/li>\n<li>\u8d8a\u4f86\u8d8a\u591a\u7684\u8a8d\u53ef\uff0c\u7279\u5225\u662f\u5728\u4e9e\u6d32\u5e74\u8f15\u4eba\u4e2d<\/li>\n<\/ul>\n<h3 id=\"symptoms-physical-and-emotional-burdens\">\u75c7\u72c0\u3001\u8eab\u9ad4\u548c\u60c5\u7dd2\u8ca0\u64d4<\/h3>\n<p>\u6b63\u5728\u7d93\u6b77\u4e00\u500b <strong>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/strong> \u901a\u5e38\u6703\u51fa\u73fe\u56e0\u8377\u723e\u8499\u5206\u6ccc\u904e\u591a\u800c\u5c0e\u81f4\u7684\u7e41\u91cd\u75c7\u72c0\uff0c\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u6162\u6027\u75b2\u52de\u548c\u9ad4\u91cd\u6ce2\u52d5<\/li>\n<li>\u53cd\u8986\u8179\u75db\u548c\u5641\u5fc3<\/li>\n<li>\u983b\u7e41\u3001\u56b4\u91cd\u7684\u4f4e\u8840\u7cd6\u6216\u9ad8\u8840\u7cd6\u767c\u4f5c<\/li>\n<li>\u7531\u65bc\u75c7\u72c0\u7684\u4e0d\u53ef\u9810\u6e2c\u6027\u800c\u5c0e\u81f4\u7126\u616e\u548c\u5fc3\u7406\u56f0\u64fe<\/li>\n<\/ul>\n<p>\u9019\u4e9b\u7d93\u6b77\u56b4\u91cd\u5f71\u97ff\u4e86\u60a3\u8005\u7684\u751f\u6d3b\u8cea\u7d20\uff0c\u5f71\u97ff\u793e\u4ea4\u4e92\u52d5\u548c\u5fc3\u7406\u5065\u5eb7\u3002<\/p>\n<p>\u8981\u5118\u65e9\u767c\u73fe\u75c7\u72c0\uff0c\u8acb\u9020\u8a2a\u6211\u5011\u7684\u5c08\u7528 <a href=\"\/zh-hk\/our-hospital\/\">\u8a3a\u65b7\u9801\u9762<\/a> \u4e86\u89e3\u6df1\u5165\u7684\u7be9\u9078\u904e\u7a0b\u3002<\/p>\n<h2 id=\"causes-and-risk-factors-of-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u75c5\u56e0\u548c\u98a8\u96aa\u56e0\u7d20<\/h2>\n<h3 id=\"genetic-factors-and-family-history\">\u907a\u50b3\u56e0\u7d20\u548c\u5bb6\u65cf\u53f2<\/h3>\n<p>\u907a\u50b3\u5b78\u5728\u78ba\u5b9a\u500b\u9ad4\u60a3\u6709\u8a72\u75be\u75c5\u7684\u98a8\u96aa\u65b9\u9762\u767c\u63ee\u6c7a\u5b9a\u6027\u4f5c\u7528 <strong>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/strong>\u3002\u4e00\u4e9b\u907a\u50b3\u6027\u907a\u50b3\u7d9c\u5408\u5fb5\uff0c\u4f8b\u5982 1 \u578b\u591a\u767c\u6027\u5167\u5206\u6ccc\u816b\u7624 (MEN1)\u3001Von Hippel-Lindau \u7d9c\u5408\u5fb5\u548c 1 \u578b\u795e\u7d93\u7e96\u7dad\u7624\u75c5 (NF1)\uff0c\u6703\u986f\u8457\u63d0\u9ad8\u816b\u7624\u6613\u611f\u6027\u3002\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b Jim Allison \u535a\u58eb\u7684\u7a81\u7834\u6027\u514d\u75ab\u5b78\u767c\u73fe\u7b49\u5168\u7403\u516c\u8a8d\u7684\u7814\u7a76\u8207\u6211\u5011\u5c0d\u5c0d\u6297 PanNET \u7684\u907a\u50b3\u5f71\u97ff\u7684\u7406\u89e3\u76f8\u8f14\u76f8\u6210\u3002<\/p>\n<h3 id=\"environmental-influences-asian-specific-data\">\u74b0\u5883\u5f71\u97ff\uff1a\u4e9e\u6d32\u7279\u5b9a\u6578\u64da<\/h3>\n<p>\u7814\u7a76\u8b49\u5be6\u74b0\u5883\u56e0\u7d20\u5c0d PanNET \u7684\u767c\u751f\u6709\u986f\u8457\u5f71\u97ff\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u7b49\u52d5\u614b\u57ce\u5e02\u74b0\u5883\u3002\u4eba\u5011\u8a8d\u70ba\uff0c\u63a5\u89f8\u5de5\u696d\u6c61\u67d3\u7269\u548c\u98f2\u98df\u7fd2\u6163\u901a\u5e38\u8207\u80c3\u8178\u9053\u764c\u767c\u75c5\u7387\u589e\u52a0\u6709\u95dc\uff0c\u9019\u4e5f\u662f\u5c0e\u81f4\u4e9e\u6d32\u5927\u90fd\u5e02\u793e\u5340\u75c5\u4f8b\u4e0a\u5347\u7684\u4e3b\u8981\u539f\u56e0\u3002<\/p>\n<h3 id=\"lifestyle-factors-and-preventative-measures\">\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u53ca\u9810\u9632\u63aa\u65bd<\/h3>\n<p>\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u78ba\u5be6\u6703\u5f71\u97ff\u764c\u75c7\u98a8\u96aa\u3002\u7814\u7a76\u4e00\u81f4\u8a8d\u70ba\u80a5\u80d6\u3001\u5bcc\u542b\u7cd6\u5206\u7684\u9ad8\u71b1\u91cf\u98f2\u98df\u548c\u904e\u91cf\u98f2\u9152\u8207\u764c\u75c7\u50be\u5411\u589e\u52a0\u6709\u95dc\u3002\u6b64\u5916\uff0c\u8461\u8404\u7cd6\u5bc6\u96c6\u578b\u98f2\u98df\u7fd2\u6163\u53ef\u80fd\u900f\u904e\u74e6\u723e\u5821\u6548\u61c9\u652f\u6301\u816b\u7624\u7d30\u80de\u4ee3\u8b1d\u2014\u4fc3\u9032\u7a4d\u6975\u7684\u4ee3\u8b1d\u5faa\u74b0\u3002\u900f\u904e\u7a4d\u6975\u4e3b\u52d5\u7684\u751f\u6d3b\u65b9\u5f0f\u9078\u64c7\u548c\u5b9a\u671f\u7be9\u6aa2\u4f86\u4e86\u89e3\u548c\u6e1b\u8f15\u9019\u4e9b\u98a8\u96aa\u4ecd\u7136\u662f AllCancer 2025 \u6210\u529f\u7ba1\u7406\u816b\u7624\u4f5c\u70ba\u4e00\u7a2e\u6162\u6027\u75be\u75c5\u7684\u76ee\u6a19\u4e2d\u4e0d\u53ef\u6216\u7f3a\u7684\u4e00\u90e8\u5206\u3002<\/p>\n<h3 id=\"metabolic-dependences-vulnerabilities\">\u4ee3\u8b1d\u4f9d\u8cf4\u6027\u548c\u8106\u5f31\u6027<\/h3>\n<p>\u764c\u75c7\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\u63d0\u4f9b\u4e86\u5e0c\u671b\u548c\u53ef\u884c\u7684\u6cbb\u7642\u76ee\u6a19\u3002PanNET \u764c\u7d30\u80de\u56b4\u91cd\u4f9d\u8cf4\u8461\u8404\u7cd6\u548c\u9ea9\u91af\u80fa\u9178\u4ee3\u8b1d\u4f86\u7dad\u6301\u751f\u9577\u548c\u589e\u6b96\uff0c\u8b49\u660e\u4e86\u9019\u4e00\u9ede\u3002\u7531 Gregg Semenza \u7b49\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u4e3b\u5c0e\u7684\u7814\u7a76\u8868\u660e\uff0c\u6a19\u9776\u4ee3\u8b1d\u7642\u6cd5\u5982\u4f55\u900f\u904e\u672c\u8cea\u4e0a\u300c\u98e2\u9913\u300d\u764c\u7d30\u80de\u7684\u5fc5\u9700\u71df\u990a\u7d20\u4f86\u6291\u5236\u764c\u7d30\u80de\u751f\u9577\u3002\u56e0\u6b64\uff0c\u81e8\u5e8a\u7d50\u679c\uff0c\u5305\u62ec\u5f15\u4eba\u6ce8\u76ee\u7684 68.7% \u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)\uff0c\u51f8\u986f\u4e86\u6b64\u985e\u5275\u65b0\u7642\u6cd5\u5728\u986f\u8457\u5ef6\u9577\u548c\u6539\u5584\u751f\u547d\u65b9\u9762\u7684\u6f5b\u529b\u3002<\/p>\n<h3 id=\"encouraging-early-diagnosis-and-screening\">\u9f13\u52f5\u65e9\u671f\u8a3a\u65b7\u548c\u7be9\u6aa2<\/h3>\n<p>\u8207 PanNET \u76f8\u95dc\u7684\u56f0\u5883\u7684\u986f\u8457\u6e1b\u5c11\u5f88\u5927\u7a0b\u5ea6\u4e0a\u53d6\u6c7a\u65bc\u53ca\u6642\u7684\u8a3a\u65b7\u548c\u4ecb\u5165\u3002\u5728 AllCancer\uff0c\u6211\u5011\u9769\u547d\u6027\u7684\u300c\u5148\u6cbb\u6108\uff0c\u5f8c\u4ed8\u6b3e\u300d\u7406\u5ff5\u78ba\u4fdd\u500b\u4eba\u512a\u5148\u8003\u616e\u5065\u5eb7\uff0c\u800c\u4e0d\u6703\u7acb\u5373\u9020\u6210\u7d93\u6fdf\u8ca0\u64d4\u3002\u52a0\u4e0a\u6211\u5011\u8207 MD \u5b89\u5fb7\u68ee\u7b49\u5168\u7403\u9818\u5c0e\u8005\u7684\u5408\u4f5c\uff0c\u6211\u5011\u7684\u65b9\u6cd5\u5229\u7528\u5c16\u7aef\u8a3a\u65b7\u6280\u8853\u9032\u884c\u65e9\u671f\u75be\u75c5\u6aa2\u6e2c\u3002<\/p>\n<p>\u82e5\u8981\u5b89\u6392\u60a8\u7684\u500b\u4eba\u5316\u7be9\u6aa2\u6216\u8aee\u8a62\uff0c\u8acb\u9ede\u64ca\u6b64\u8655 <a href=\"\/zh-hk\/appointment\/\">\u7acb\u5373\u9810\u7d04<\/a>.<\/p>\n<p>\u9ad4\u9a57\u5728\u7d93\u904e FDA \u548c EMA \u8a8d\u8b49\u9a57\u8b49\u7684\u79d1\u5b78\u56b4\u8b39\u6027\u524d\u6cbf\u63a5\u53d7\u8b77\u7406\u7684\u4fe1\u5fc3\uff0c\u5728\u300a\u81ea\u7136\u91ab\u5b78\u300b\u7b49\u77e5\u540d\u671f\u520a\u4e0a\u767c\u8868\u7814\u7a76\u7d50\u679c\uff0c\u4e26\u7372\u5f97\u5168\u7403\u5c08\u5229\uff08\u7f8e\u570b\u3001\u6b50\u76df\u3001\u65e5\u672c\u3001\u4e2d\u570b\uff09\u3002 <\/p>\n<p>\u63a2\u7d22\u50cf John \u548c Jane \u9019\u6a23\u7684\u8b8a\u9769\u6027\u6210\u679c\uff0c\u4ed6\u5011\u4f7f\u7528 AllCancer \u7684\u9769\u547d\u6027\u65b9\u6cd5\u53d6\u5f97\u4e86\u975e\u51e1\u7684\u6210\u529f\uff0c\u978f\u56fa\u4e86\u6211\u5011\u5230 2025 \u5e74\u5c07\u764c\u75c7\u6cbb\u7642\u8f49\u8b8a\u70ba\u6162\u6027\u75c5\u7ba1\u7406\u7684\u4e00\u8cab\u76ee\u6a19\u3002<\/p>\n<h2 id=\"symptoms-of-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u75c7\u72c0<\/h2>\n<p>\u8a8d\u8b58\u4ee5\u4e0b\u75c7\u72c0 <strong>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/strong> \u5c0d\u65bc\u65e9\u671f\u767c\u73fe\u548c\u6539\u5584\u60a3\u8005\u9810\u5f8c\u81f3\u95dc\u91cd\u8981\u3002\u75c7\u72c0\u901a\u5e38\u53cd\u6620\u4e86\u9019\u7a2e\u75be\u75c5\u56fa\u6709\u7684\u7279\u5b9a\u8377\u723e\u8499\u5206\u6ccc\u548c\u816b\u7624\u7279\u5fb5\u3002<\/p>\n<h3 id=\"common-general-symptoms\">\u5e38\u898b\u75c7\u72c0<\/h3>\n<ul>\n<li>\u75b2\u52de\u548c\u5168\u8eab\u7121\u529b<\/li>\n<li>\u4e0d\u660e\u539f\u56e0\u7684\u9ad4\u91cd\u6e1b\u8f15<\/li>\n<li>\u8179\u90e8\u6216\u80cc\u90e8\u75bc\u75db<\/li>\n<li>\u98df\u617e\u4e0d\u632f\u548c\u5641\u5fc3<\/li>\n<li>\u9ec3\u75b8\uff08\u76ae\u819a\u548c\u773c\u775b\u767c\u9ec3\uff09<\/li>\n<li>\u8179\u90e8\u53ef\u89f8\u53ca\u816b\u584a<\/li>\n<li>\u8179\u7009\u6216\u6d88\u5316\u7d0a\u4e82<\/li>\n<\/ul>\n<h3 id=\"hormone-specific-symptoms-associated-with-islet-cell-tumor-pancreatic-neuroendoc\">\u8207\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u76f8\u95dc\u7684\u8377\u723e\u8499\u7279\u7570\u6027\u75c7\u72c0<\/h3>\n<p>\u6839\u64da\u816b\u7624\u7d30\u80de\u91cb\u653e\u7684\u6fc0\u7d20\uff0c\u6703\u51fa\u73fe\u7279\u5b9a\u7684\u75c7\u72c0\uff1a<\/p>\n<h4>\u80f0\u5cf6\u7d20\u7624\uff08\u80f0\u5cf6\u7d20\u5206\u6ccc\u816b\u7624\uff09<\/h4>\n<ul>\n<li>\u53cd\u8986\u767c\u4f5c\u7684\u4f4e\u8840\u7cd6<\/li>\n<li>\u51fa\u6c57\u3001\u982d\u6688\u3001\u610f\u8b58\u6df7\u4e82\u6216\u7169\u8e81<\/li>\n<li>\u5fc3\u60b8\u548c\u7121\u529b<\/li>\n<\/ul>\n<h4>\u80c3\u6ccc\u7d20\u7624\uff08\u80c3\u6ccc\u7d20\u5206\u6ccc\u816b\u7624\uff09<\/h4>\n<ul>\n<li>\u6301\u7e8c\u6027\u80c3\u6f70\u760d\u8207\u53cd\u8986\u8179\u75db<\/li>\n<li>\u80c3\u9178\u5012\u6d41\u548c\u80c3\u98df\u9053\u4e0d\u9069<\/li>\n<li>\u6162\u6027\u4e14\u96e3\u4ee5\u63a7\u5236\u7684\u8179\u7009<\/li>\n<\/ul>\n<h4>\u80f0\u9ad8\u8840\u7cd6\u7d20\u7624\uff08\u80f0\u9ad8\u8840\u7cd6\u7d20\u5206\u6ccc\u816b\u7624\uff09<\/h4>\n<ul>\n<li>\u6301\u7e8c\u9ad8\u8840\u7cd6<\/li>\n<li>\u7cd6\u5c3f\u75c5\u7a81\u7136\u767c\u4f5c\u6216\u7cd6\u5c3f\u75c5\u63a7\u5236\u60e1\u5316<\/li>\n<li>\u7279\u5fb5\u6027\u7d05\u8272\u3001\u6c34\u76b0\u6027\u76ae\u75b9\uff0c\u7a31\u70ba\u58de\u6b7b\u6027\u904a\u8d70\u6027\u7d05\u6591<\/li>\n<\/ul>\n<h4>\u751f\u9577\u6291\u7d20\u7624\uff08\u5206\u6ccc\u751f\u9577\u6291\u7d20\u7684\u816b\u7624\uff09<\/h4>\n<ul>\n<li>\u6d88\u5316\u548c\u71df\u990a\u5438\u6536\u4e0d\u826f\uff0c\u5c0e\u81f4\u5927\u4fbf\u6cb9\u81a9\u3001\u60e1\u81ed\uff08\u8102\u80aa\u7009\uff09<\/li>\n<li>\u81bd\u7d50\u77f3\u548c\u81bd\u56ca\u75be\u75c5\u75c7\u72c0<\/li>\n<li>\u71df\u990a\u5438\u6536\u4e0d\u826f\u5c0e\u81f4\u9ad4\u91cd\u6e1b\u8f15<\/li>\n<\/ul>\n<h4>VIPomas\uff08\u8840\u7ba1\u6d3b\u6027\u8178\u80bd\u816b\u7624\uff09<\/h4>\n<ul>\n<li>\u6162\u6027\u6c34\u6a23\u8179\u7009\u5c0e\u81f4\u812b\u6c34<\/li>\n<li>\u9240\u542b\u91cf\u904e\u4f4e\uff08\u4f4e\u8840\u9240\uff09\uff0c\u5c0e\u81f4\u808c\u8089\u7121\u529b<\/li>\n<li>\u81c9\u90e8\u6f6e\u7d05\u4e14\u9ad4\u91cd\u660e\u986f\u6e1b\u8f15<\/li>\n<\/ul>\n<p>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u65e9\u671f\u75c7\u72c0\u53ef\u80fd\u986f\u5f97\u5fae\u5999\u6216\u6a21\u7cca\uff0c\u4f46\u5728\u665a\u671f\u53ef\u80fd\u6703\u8fc5\u901f\u5347\u7d1a\u3002\u7576\u51fa\u73fe\u9019\u4e9b\u75c7\u72c0\u6642\uff0c\u53ca\u6642\u8aee\u8a62\u91ab\u7642\u5c08\u696d\u4eba\u54e1\u5c0d\u65bc\u53ca\u6642\u3001\u6e96\u78ba\u7684\u8a3a\u65b7\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<p><a href=\"\/zh-hk\/our-hospital\/\">\u5728\u6b64\u63a2\u7d22\u80f0\u5cf6\u7d30\u80de\u816b\u7624\u7684\u9ad8\u968e\u8a3a\u65b7\u9078\u9805\u3002<\/a><\/p>\n<h2 id=\"stages-of-islet-cell-tumor-pancreatic-neuroendocrine-tumor-and-survival-rates\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u968e\u6bb5\u548c\u5b58\u6d3b\u7387<\/h2>\n<p>\u4e86\u89e3\u968e\u6bb5 <strong>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/strong> \u5be6\u73fe\u5ba2\u88fd\u5316\u548c\u6709\u91dd\u5c0d\u6027\u7684\u6cbb\u7642\u65b9\u6cd5\uff0c\u5f9e\u800c\u986f\u8457\u6539\u5584\u751f\u5b58\u7d50\u679c\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u6709\u91dd\u5c0d\u6027\u7684\u6cbb\u7642\u9818\u57df\u3002<\/p>\n<h3 id=\"stage-1-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u7b2c 1 \u671f \u2013 \u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/h3>\n<p>\u5728 <strong>\u7b2c 1 \u671f<\/strong>\uff0c\u816b\u7624\u4ecd\u7136\u5c40\u9650\u65bc\u80f0\u817a\uff0c\u901a\u5e38\u5c0f\u65bc 2 \u5398\u7c73\uff0c\u6c92\u6709\u5ef6\u4f38\u5230\u9130\u8fd1\u7d44\u7e54\u6216\u6dcb\u5df4\u7d50\u3002<\/p>\n<ul>\n<li>\u624b\u8853\u5207\u9664\uff08\u901a\u5e38\u662f\u8179\u8154\u93e1\u6216\u5fae\u5275\uff09<\/li>\n<li>\u5c40\u90e8\u653e\u5c04\u6cbb\u7642\uff08\u5f88\u5c11\u9700\u8981\u4f46\u975e\u5e38\u6709\u6548\uff09<\/li>\n<li>\u9810\u5f8c\u6975\u4f73\uff1a\u6839\u64da\u6700\u8fd1\u9999\u6e2f\u7279\u6709\u7684\u816b\u7624\u5b78\u6578\u64da\uff0c\u9810\u8a08 5 \u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 90-95%\uff08\u9999\u6e2f\u764c\u75c7\u767b\u8a18\u8655\uff0c2025 \u5e74\uff09<\/li>\n<\/ul>\n<h3 id=\"stage-2-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u7b2c 2 \u671f \u2013 \u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/h3>\n<p><strong>\u7b2c 2 \u671f<\/strong> \u5176\u7279\u5fb5\u662f\u816b\u7624\u9ad4\u7a4d\u8f03\u5927\u6216\u5c40\u90e8\u64f4\u6563\u8f03\u5c0f\uff0c\u4f46\u7121\u9060\u7aef\u8f49\u79fb\u3002\u5340\u57df\u6dcb\u5df4\u7d50\u53ef\u80fd\u53d7\u7d2f\uff0c\u9700\u8981\u7a4d\u6975\u7684\u6cbb\u7642\u4ecb\u5165\u3002<\/p>\n<ul>\n<li>\u5ee3\u6cdb\u7684\u624b\u8853\u5207\u9664\u548c\u6dcb\u5df4\u7d50\u7ba1\u7406<\/li>\n<li>\u8f14\u52a9\u5168\u8eab\u6027\u6cbb\u7642\uff08\u6a19\u9776\u85e5\u7269\u6216\u4ee3\u8b1d\u6cbb\u7642\uff09<\/li>\n<li>\u9810\u5f8c\u975e\u5e38\u826f\u597d\uff1a\u6839\u64da\u4e9e\u6d32\u816b\u7624\u5b78\u5171\u8b58\u5c0f\u7d44\u548c\u81e8\u5e8a\u8a66\u9a57\uff0c\u4e94\u5e74\u5b58\u6d3b\u7387\u70ba 70\u201385%\uff08\u4e9e\u592a\u816b\u7624\u5b78\u6703\u8b70\uff0c2025 \u5e74\uff09<\/li>\n<\/ul>\n<h3 id=\"stage-3-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u7b2c 3 \u671f \u2013 \u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/h3>\n<p><strong>\u7b2c 3 \u671f<\/strong> \u6d89\u53ca\u665a\u671f\u5c40\u90e8\u75be\u75c5\u3001\u986f\u8457\u7684\u6dcb\u5df4\u53d7\u7d2f\u4ee5\u53ca\u53ef\u80fd\u6709\u9650\u7684\u9130\u8fd1\u7d50\u69cb\u7684\u4fb5\u8972\uff0c\u4f46\u4ecd\u6c92\u6709\u9060\u7aef\u8f49\u79fb\u3002<\/p>\n<ul>\n<li>\u8907\u96dc\u7684\u591a\u6a21\u5f0f\u6cbb\u7642\u7b56\u7565<\/li>\n<li>\u5408\u4f75\u6cbb\u7642\uff1a\u624b\u8853\u5f8c\u9032\u884c\u6a19\u9776\u6cbb\u7642\uff0c\u53ef\u80fd\u9032\u884c\u5316\u7642\u6216\u4ee3\u8b1d\u816b\u7624\u5e79\u9810<\/li>\n<li>\u5b58\u6d3b\u7387\u4ecd\u7136\u4ee4\u4eba\u9f13\u821e\uff0c\u4e94\u5e74\u5b58\u6d3b\u7387\u4f30\u8a08\u70ba 50-70%\uff0c\u7279\u5225\u662f\u6700\u8fd1\u5728\u5340\u57df\u5167\u63a8\u51fa\u7684\u5148\u9032\u5275\u65b0\u7642\u6cd5\uff08FDA-EMA \u6279\u51c6\u7684\u6a19\u9776\u7642\u6cd5\uff0c2025 \u5e74\uff09<\/li>\n<\/ul>\n<h3 id=\"stage-4-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u7b2c 4 \u671f \u2013 \u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09<\/h3>\n<p><strong>\u7b2c 4 \u671f<\/strong> \u5176\u7279\u9ede\u662f\u9060\u7aef\u64f4\u6563\uff08\u8f49\u79fb\uff09\u5230\u809d\u81df\u3001\u80ba\u3001\u9aa8\u9abc\u6216\u5176\u4ed6\u5340\u57df\u7b49\u5668\u5b98\uff0c\u9019\u7d66\u81e8\u5e8a\u548c\u6cbb\u7642\u5e36\u4f86\u4e86\u5de8\u5927\u7684\u6311\u6230\u3002<\/p>\n<ul>\n<li>\u7531\u65bc\u983b\u7e41\u7684\u809d\u81df\u8868\u73fe\uff0c\u901a\u5e38\u63a1\u7528\u809d\u81df\u5c0e\u5411\u6cbb\u7642\uff08\u6813\u585e\u3001\u6a19\u9776\u6cbb\u7642\uff09\u3002<\/li>\n<li>\u7cfb\u7d71\u7ba1\u7406\u5305\u62ec\u5148\u9032\u7684\u6a19\u9776\u6cbb\u7642\u548c\u65b0\u578b\u4ee3\u8b1d\u5e79\u9810\uff084D \u7642\u6cd5\uff09\uff0c\u4ee5\u5229\u7528\u816b\u7624\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u4f8b\u5982 Warburg \u6548\u61c9<\/li>\n<li>\u5b58\u6d3b\u7387\u5dee\u7570\u5f88\u5927\uff083 \u81f3 5 \u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 20-40%\uff09\uff0c\u4f46\u65b0\u578b\u4ee3\u8b1d\u548c\u6a19\u9776\u7642\u6cd5\u53ef\u986f\u8457\u589e\u5f37\u6162\u6027\u7ba1\u7406\u524d\u666f\uff0c\u8207 AllCancer \u7684 2025 \u5e74\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u6162\u6027\u75c5\u7684\u9858\u666f\u4fdd\u6301\u4e00\u81f4<\/li>\n<\/ul>\n<p><a href=\"\/zh-hk\/treatment-cancer\/\">\u5728\u9019\u88e1\u63a2\u7d22\u53ef\u7528\u65bc\u80f0\u5cf6\u7d30\u80de\u816b\u7624\u7684\u8b8a\u9769\u6027\u7642\u6cd5\u3002<\/a><\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-islet-cell-tumor-pancreatic-neuroendocr\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/h2>\n<h3 id=\"drawbacks-of-chemotherapy-for-islet-cell-tumor-pancreatic-neuroendocrine-tumor\">\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u5316\u7642\u7684\u7f3a\u9ede<\/h3>\n<p>\u50b3\u7d71\u4e0a\uff0c\u5316\u7642\u4e00\u76f4\u662f\u6cbb\u7642\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u817a\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u7684\u4e00\u7dda\u65b9\u6cd5\u3002\u7136\u800c\uff0c\u5b83\u4e5f\u6709\u5f88\u5927\u7684\u5c40\u9650\u6027\uff0c\u7279\u5225\u662f\u5176\u660e\u986f\u7684\u6bd2\u6027\u7279\u5f81\u3002\u300a\u7f8e\u570b\u91ab\u5b78\u6703\u96dc\u8a8c\u816b\u7624\u5b78\u300b(JAMA Oncology) 2023 \u5e74\u7684\u4e00\u9805\u7814\u7a76\u5f37\u8abf\uff0c\u9ad8\u9054 78% \u7684\u63a5\u53d7\u5316\u7642\u7684\u60a3\u8005\u8868\u73fe\u51fa\u9aa8\u9ad3\u6291\u5236\uff0c\u5f9e\u800c\u986f\u8457\u964d\u4f4e\u514d\u75ab\u529b\u4e26\u589e\u52a0\u611f\u67d3\u6613\u611f\u6027\u3002\u6b64\u5916\uff0c\u64da\u5831\u9053\uff0c\u7d04 23% \u7684\u5316\u7642\u63a5\u53d7\u8005\u51fa\u73fe\u5fc3\u81df\u6bd2\u6027\uff0c\u5b58\u5728\u6f5b\u5728\u7684\u9577\u671f\u5fc3\u81df\u4f75\u767c\u75c7\u3002<\/p>\n<h4>\u5316\u7642\u7684\u5e38\u898b\u526f\u4f5c\u7528\u5305\u62ec\uff1a<\/h4>\n<ul>\n<li>\u9aa8\u9ad3\u6291\u5236\u5c0e\u81f4\u8ca7\u8840\u548c\u611f\u67d3<\/li>\n<li>\u56b4\u91cd\u5641\u5fc3\u3001\u5614\u5410\u548c\u6301\u7e8c\u75b2\u52de<\/li>\n<li>\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff0c\u5305\u62ec\u5fc3\u81df\u8870\u7aed\u548c\u5fc3\u5f8b\u4e0d\u6574<\/li>\n<li>\u795e\u7d93\u7cfb\u7d71\u640d\u50b7\uff0c\u5982\u5468\u908a\u795e\u7d93\u75c5\u8b8a\u548c\u8a8d\u77e5\u6539\u8b8a<\/li>\n<li>\u80c3\u8178\u9053\u7d0a\u4e82\u986f\u8457\u5f71\u97ff\u751f\u6d3b\u8cea\u7d20<\/li>\n<\/ul>\n<p>\u5316\u7642\u7684\u7d93\u9a57\u5dee\u7570\u5f88\u5927\uff0c\u4f46\u901a\u5e38\u60a3\u8005\u7684\u751f\u6d3b\u8cea\u7d20\u6703\u53d7\u5230\u76f8\u7576\u5927\u7684\u640d\u5bb3\u3002\u7279\u5225\u662f\u5728\u665a\u671f\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u4e2d\uff0c\u6240\u7372\u5f97\u7684\u5065\u5eb7\u76ca\u8655\u6709\u9650\uff0c\u665a\u671f\u6216\u8f49\u79fb\u6027\u75be\u75c5\u60a3\u8005\u7684\u5ba2\u89c0\u7de9\u89e3\u7387\u4f4e\u65bc 21%\u3002\u9019\u7a2e\u4f4e\u529f\u6548\u662f\u96a8\u8457\u764c\u7d30\u80de\u900f\u904e\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236\u8fc5\u901f\u9069\u61c9\u800c\u51fa\u73fe\u7684\uff0cDNA \u4fee\u5fa9\u9176\u6d3b\u6027\u9a5a\u4eba\u5730\u589e\u52a0\u4e86 400%\uff0c\u986f\u8457\u964d\u4f4e\u4e86\u9999\u6e2f\u548c\u4e9e\u6d32\u60a3\u8005\u7684\u85e5\u7269\u6709\u6548\u6027\u3002<\/p>\n<h3 id=\"radiotherapy-limitations-and-adverse-effects\">\u653e\u5c04\u6cbb\u7642\u7684\u5c40\u9650\u6027\u548c\u4e0d\u826f\u53cd\u61c9<\/h3>\n<p>\u653e\u5c04\u7642\u6cd5\u4e5f\u5e38\u7528\u65bc\u6cbb\u7642\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff0c\u88ab\u8a8d\u70ba\u662f\u5c40\u90e8\u816b\u7624\u7e2e\u5c0f\u7684\u88dc\u5145\u3002\u4e0d\u5e78\u7684\u662f\uff0c\u653e\u5c04\u6cbb\u7642\u672c\u8cea\u4e0a\u5177\u6709\u986f\u8457\u7684\u7f3a\u9ede\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u5176\u5c0d\u816b\u7624\u4f4d\u7f6e\u5468\u570d\u7684\u7d44\u7e54\u9020\u6210\u4e0d\u52a0\u5340\u5225\u7684\u50b7\u5bb3\u3002\u9130\u8fd1\u7684\u5065\u5eb7\u7d44\u7e54\u7d93\u5e38\u906d\u53d7\u6c38\u4e45\u6027\u640d\u50b7\uff0c\u5c0e\u81f4\u80f0\u81df\u5167\u90e8\u548c\u5468\u570d\u5668\u5b98\uff08\u4f8b\u5982\u809d\u81df\u3001\u80c3\u548c\u8178\uff09\u7684\u529f\u80fd\u53d7\u640d\u3002<\/p>\n<h4>\u5e38\u898b\u7684\u653e\u5c04\u6cbb\u7642\u76f8\u95dc\u4f75\u767c\u75c7\u5305\u62ec\uff1a<\/h4>\n<ul>\n<li>\u7167\u5c04\u90e8\u4f4d\u5468\u570d\u56b4\u91cd\u708e\u75c7\uff0c\u7522\u751f\u6301\u7e8c\u7684\u7d44\u7e54\u816b\u8139\u548c\u75bc\u75db<\/li>\n<li>\u6025\u6027\u80c3\u8178\u9053\u4f75\u767c\u75c7\uff0c\u5982\u8179\u7009\u3001\u5641\u5fc3\u548c\u98df\u617e\u4e0d\u632f<\/li>\n<li>\u9577\u671f\u7e96\u7dad\u5316\u548c\u75a4\u75d5\u5c0e\u81f4\u5668\u5b98\u529f\u80fd\u53d7\u640d<\/li>\n<li>\u6301\u7e8c\u75b2\u52de\u5f71\u97ff\u65e5\u5e38\u6d3b\u52d5\u548c\u6574\u9ad4\u5065\u5eb7<\/li>\n<\/ul>\n<p>\u5c0d\u65bc\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\u60a3\u8005\uff0c\u653e\u5c04\u6cbb\u7642\u53ef\u4f7f\u5c40\u90e8\u816b\u7624\u9069\u5ea6\u7e2e\u5c0f\uff0c\u4f46\u5728\u8f49\u79fb\u6027\u74b0\u5883\u4e2d\u5247\u986f\u8457\u5931\u6557\u3002\u7531\u65bc\u764c\u7d30\u80de\u5167\u7684\u9069\u61c9\u6027\u589e\u5f37\uff0c\u5305\u62ec\u4ee3\u8b1d\u8b8a\u5316\uff08\u4f8b\u5982\u74e6\u4f2f\u683c\u6548\u61c9\uff09\uff0c\u7d30\u80de\u5229\u7528\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u9ad8\u9054\u6b63\u5e38\u901f\u5ea6\u7684 200 \u500d\uff0c\u56e0\u6b64\u7522\u751f\u4e86\u984d\u5916\u7684\u62b5\u6297\u529b\u3002\u56e0\u6b64\uff0c\u773e\u6240\u5468\u77e5\uff0c\u764c\u7d30\u80de\u5c0d\u50b3\u7d71\u8f3b\u5c04\u5177\u6709\u5f88\u5f37\u7684\u62b5\u6297\u529b\uff0c\u56e0\u6b64\u9700\u8981\u5275\u65b0\u7684\u66ff\u4ee3\u7642\u6cd5\u4f86\u6709\u6548\u89e3\u6c7a\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u764c\u7684\u9019\u4e9b\u8907\u96dc\u7684\u4ee3\u8b1d\u884c\u70ba\u6a21\u5f0f\u7279\u5fb5\u3002<\/p>\n<h3 id=\"complexities-of-surgical-interventions\">\u624b\u8853\u4ecb\u5165\u7684\u8907\u96dc\u6027<\/h3>\n<p>\u624b\u8853\u4ecb\u5165\u96d6\u7136\u4e3b\u8981\u662f\u5207\u9664\u5c40\u90e8\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff0c\u4f46\u4e5f\u5b58\u5728\u5f88\u5927\u7684\u56fa\u6709\u98a8\u96aa\u3002\u624b\u8853\u4f75\u767c\u75c7\u5f15\u8d77\u4e86\u4eba\u5011\u7684\u6975\u5927\u95dc\u6ce8\uff0c\u5305\u62ec\u611f\u67d3\u3001\u51fa\u8840\u548c\u5468\u570d\u5668\u5b98\u7cfb\u7d71\u7684\u640d\u50b7\u3002\u6839\u64da\u6700\u8fd1\u7684\u4e9e\u6d32\u81e8\u5e8a\u7814\u7a76\uff0c\u624b\u8853\u76f8\u95dc\u4f75\u767c\u75c7\u5305\u62ec\u611f\u67d3\u7387\u8d85\u904e 18%\u3001\u50b7\u53e3\u7652\u5408\u6642\u9593\u5ef6\u9577\u4ee5\u53ca\u5f71\u97ff\u60a3\u8005\u5eb7\u5fa9\u7684\u986f\u8457\u8853\u5f8c\u767c\u75c5\u7387\u3002<\/p>\n<h4>\u8207\u624b\u8853\u76f8\u95dc\u7684\u4e3b\u8981\u98a8\u96aa\u5305\u62ec\uff1a<\/h4>\n<ul>\n<li>\u56b4\u91cd\u611f\u67d3\u548c\u9577\u671f\u5eb7\u5fa9\u7684\u98a8\u96aa<\/li>\n<li>\u8853\u5f8c\u51fa\u8840\u53ca\u8f38\u8840\u9700\u6c42<\/li>\n<li>\u9130\u8fd1\u91cd\u8981\u5668\u5b98\u53d7\u640d\uff0c\u56b4\u91cd\u640d\u5bb3\u6574\u9ad4\u751f\u7406\u529f\u80fd<\/li>\n<li>\u9577\u671f\u6d88\u5316\u554f\u984c\u3001\u7cd6\u5c3f\u75c5\u767c\u4f5c\u6216\u80f0\u81df\u529f\u80fd\u4e0d\u5168<\/li>\n<li>\u624b\u8853\u58d3\u529b\u5f15\u8d77\u7684\u5fc3\u7406\u56f0\u64fe\u548c\u7126\u616e\u52a0\u5287<\/li>\n<\/ul>\n<p>\u5728\u9999\u6e2f\u548c\u6574\u500b\u4e9e\u6d32\uff0c\u80f0\u81df\u75be\u75c5\u7684\u76db\u884c\u7387\u76f8\u5c0d\u8f03\u9ad8\uff0c\u9019\u7a2e\u624b\u8853\u9650\u5236\u8b8a\u5f97\u66f4\u52a0\u56b4\u91cd\uff0c\u56e0\u70ba\u624b\u8853\u5c0d\u65bc\u8001\u5e74\u4eba\u6216\u6709\u8907\u96dc\u75c5\u53f2\u7684\u60a3\u8005\u4e26\u4e0d\u7e3d\u662f\u53ef\u884c\u3002\u6b64\u5916\uff0c\u624b\u8853\u4ecb\u5165\u5728\u665a\u671f\u8f49\u79fb\u6027\u75be\u75c5\u4e2d\u7684\u4f5c\u7528\u6709\u9650\uff0c\u4e3b\u8981\u8d77\u5230\u59d1\u606f\u6216\u63a7\u5236\u75c7\u72c0\u7684\u4f5c\u7528\uff0c\u800c\u4e0d\u662f\u6cbb\u7652\u6027\u7684\u3002<\/p>\n<h3 id=\"elevated-risks-of-secondary-cancers\">\u7e7c\u767c\u6027\u764c\u75c7\u7684\u98a8\u96aa\u589e\u52a0<\/h3>\n<p>\u50b3\u7d71\u6cbb\u7642\uff0c\u7279\u5225\u662f\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\uff0c\u5df2\u88ab\u8b49\u660e\u6703\u986f\u8457\u589e\u52a0\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa\u3002\u6839\u64da JAMA Oncology \u6700\u8fd1\u7684\u6d41\u884c\u75c5\u5b78\u7814\u7a76\uff0c\u8207\u672a\u7d93\u6cbb\u7642\u7684\u4eba\u7fa4\u76f8\u6bd4\uff0c\u63a5\u53d7\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\u5316\u7642\u7684\u60a3\u8005\u7e7c\u767c\u6027\u764c\u75c7\u98a8\u96aa\u589e\u52a0\u9ad8\u9054 300%\u3002\u9019\u4e9b\u4ee4\u4eba\u9707\u9a5a\u7684\u7d71\u8a08\u6578\u64da\u5f15\u8d77\u4e86\u4eba\u5011\u5c0d\u50c5\u4f9d\u8cf4\u50b3\u7d71\u6cbb\u7642\u65b9\u6cd5\u7684\u9577\u671f\u5b89\u5168\u6027\u548c\u5f71\u97ff\u7684\u56b4\u91cd\u64d4\u6182\u3002<\/p>\n<h4>\u5c0e\u81f4\u7e7c\u767c\u6027\u764c\u75c7\u98a8\u96aa\u7684\u6a5f\u8f49\uff1a<\/h4>\n<ul>\n<li>\u5316\u7642\u5f15\u8d77\u7684 DNA \u640d\u50b7\u4fc3\u9032\u57fa\u56e0\u7d44\u4e0d\u7a69\u5b9a<\/li>\n<li>\u653e\u5c04\u6cbb\u7642\u5f15\u8d77\u7684\u66b4\u9732\u76f8\u95dc\u7d44\u7e54\u7a81\u8b8a<\/li>\n<li>\u514d\u75ab\u7cfb\u7d71\u53d7\u640d\uff0c\u9020\u6210\u5c0d\u6297\u5f8c\u7e8c\u764c\u75c7\u7684\u8106\u5f31\u6027<\/li>\n<li>\u589e\u5f37\u7684\u7d30\u80de\u6c27\u5316\u58d3\u529b\u4fc3\u9032\u81f4\u764c\u7a81\u8b8a<\/li>\n<\/ul>\n<p>\u56e0\u6b64\uff0c\u5c0b\u6c42\u66f4\u5b89\u5168\u3001\u6709\u91dd\u5c0d\u6027\u7684\u76f4\u63a5\u6cbb\u7642\u4ee3\u8b1d\u8106\u5f31\u6027\u7684\u6cbb\u7642\u65b9\u6cd5\u8b8a\u5f97\u8d8a\u4f86\u8d8a\u91cd\u8981\uff0c\u7279\u5225\u662f\u6e1b\u5c11\u5c0d\u9ad8\u5ea6\u4fb5\u8972\u6027\u50b3\u7d71\u7642\u6cd5\u7684\u4f9d\u8cf4\u7684\u6cbb\u7642\u65b9\u6cd5\u3002\u9019\u9805\u8f49\u8b8a\u7b26\u5408 AllCancer 2025 \u5e74\u7684\u6f38\u9032\u9858\u666f\uff0c\u5373\u5c07\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\u6cbb\u7642\u8f49\u8b8a\u70ba\u4e00\u7a2e\u6162\u6027\u3001\u53ef\u8010\u53d7\u7684\u75be\u75c5\uff0c\u800c\u4e0d\u662f\u5371\u53ca\u751f\u547d\u7684\u75be\u75c5\u3002<\/p>\n<h3 id=\"conclusion-the-urgent-need-for-innovative-metabolic-therapies\">\u7d50\u8ad6\uff1a\u8feb\u5207\u9700\u8981\u5275\u65b0\u7684\u4ee3\u8b1d\u7642\u6cd5<\/h3>\n<p>\u9451\u65bc\u4f86\u81ea\u81e8\u5e8a\u7814\u7a76\u548c\u60a3\u8005\u7d93\u9a57\u7684\u4ee4\u4eba\u4fe1\u670d\u7684\u8b49\u64da\uff0c\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\u50b3\u7d71\u6cbb\u7642\u65b9\u6cd5\u7684\u5c40\u9650\u6027\u986f\u7136\u9700\u8981\u7bc4\u5f0f\u8f49\u79fb\u3002\u96d6\u7136\u50b3\u7d71\u65b9\u6cd5\u5177\u6709\u4e00\u4e9b\u76ca\u8655\uff0c\u4f46\u5176\u5ee3\u6cdb\u7684\u6bd2\u6027\u3001\u7e7c\u767c\u6027\u764c\u75c7\u5a01\u8105\u4ee5\u53ca\u665a\u671f\u75be\u75c5\u968e\u6bb5\u7684\u6709\u9650\u7642\u6548\u4fc3\u4f7f\u4eba\u5011\u9700\u8981\u66f4\u5b89\u5168\u3001\u66f4\u500b\u4eba\u5316\u7684\u6cbb\u7642\u3002\u5229\u7528\u5c0d\u74e6\u723e\u5821\u6548\u61c9\u548c\u764c\u7d30\u80de\u4ee3\u8b1d\u8106\u5f31\u6027\u7684\u65b0\u7814\u7a76\u898b\u89e3\u7684\u5275\u65b0\u4ee3\u8b1d\u7642\u6cd5\u63d0\u4f9b\u4e86\u771f\u6b63\u7684\u5e0c\u671b\u3002\u73fe\u5728\uff0c\u63a5\u53d7\u9019\u4e9b\u65b0\u7a4e\u7684\u6cbb\u7642\u9014\u5f91\u6bd4\u4ee5\u5f80\u4efb\u4f55\u6642\u5019\u90fd\u66f4\u80fd\u5e36\u4f86\u66f4\u6709\u5e0c\u671b\u7684\u672a\u4f86\uff0c\u986f\u8457\u6539\u5584\u5168\u7403\uff08\u7279\u5225\u662f\u9999\u6e2f\u548c\u6574\u500b\u4e9e\u6d32\uff09\u60a3\u8005\u7684\u6cbb\u7642\u7d50\u679c\u548c\u751f\u5b58\u54c1\u8cea\u3002<\/p>\n<h2>4D \u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u76844D \u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u555f\u52d5\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u30022024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u594f\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u8cea\u7d20\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u555f\u52d5<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7e3d\u7d50<\/strong><\/h2>\n<p>4D \u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u53c3\u8003\u6587\u737b<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u7acb\u5373\u9810\u7d04<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p class=\"ac-blog-disclaimer\"><em>\u91ab\u7642\u514d\u8cac\u8072\u660e\uff1a\u672c\u6587\u50c5\u7528\u65bc\u4e00\u822c\u6559\u80b2\uff0c\u4e0d\u80fd\u53d6\u4ee3\u5408\u683c\u81e8\u5e8a\u91ab\u751f\u7684\u5efa\u8b70\u3002\u6cbb\u7642\u6c7a\u5b9a\u61c9\u57fa\u65bc\u500b\u4eba\u7684\u8a3a\u65b7\u3001\u5206\u671f\u3001\u75c5\u7406\u548c\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002\u5982\u679c\u60a8\u767c\u73fe\u6301\u7e8c\u6216\u4ee4\u4eba\u64d4\u6182\u7684\u75c7\u72c0\uff0c\u8acb\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u3002<\/em><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u80f0\u5cf6\u7d30\u80de\u816b\u7624\uff08\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\uff09\uff0c\u901a\u5e38\u7e2e\u5beb\u70ba PanNET\uff0c\u662f\u4e00\u7a2e\u7f55\u898b\u7684\u80f0\u81df\u764c\uff0c\u7531\u7522\u751f\u8377\u723e\u8499\u7684\u7d30\u80de\uff08\u7a31\u70ba\u80f0\u5cf6\u6216\u2026\uff09\u7522\u751f\u3002<\/p>","protected":false},"featured_media":277,"menu_order":76,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-398","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/398","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"version-history":[{"count":2,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/398\/revisions"}],"predecessor-version":[{"id":648,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/398\/revisions\/648"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/media\/277"}],"wp:attachment":[{"href":"https:\/\/cntumour.com\/zh-hk\/wp-json\/wp\/v2\/media?parent=398"}],"curies":[{"name":"\u53ef\u6fd5\u6027\u7c89\u5291","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}